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Merck
CN

SAB4501325

Anti-MGLUR7 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

GPRC1G, GRM7, MGLUR7, mGluR7, otein name Metabotropic glutamate receptor 7

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Anti-MGLUR7 antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 102 kDa

species reactivity

mouse, human, rat

concentration

~1 mg/mL

technique(s)

ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

Q14831

UniProt accession no.

Q14831

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... GRM7(2917)

Related Categories

Biochem/physiol Actions

The gene coding MGLUR7 (glutamate metabotropic receptor 7) is associated with autism. GRM7 participates in the initiation of glutamate receptor. It also participates in schizophrenia and bipolar disorder.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Anti-MGLUR7 Antibody detects endogenous levels of total MGLUR7 protein.
MGLUR7 (glutamate metabotropic receptor 7) is coded by the glutamate receptor, metabotropic 7 (GRM7) gene. It is expressed in several parts of the central nervous system. mGluR7 is located in the presynaptic zone of the synaptic cleft of glutamatergic synapses. GRM7 gene is mapped to human chromosome 3p26. Anti-MGLUR7 Antibody detects endogenous levels of total MGLUR7 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human mGluR7.

Immunogen Range: 866-915

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
310211

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A polymorphism of the metabotropic glutamate receptor mGluR7 (GRM7) gene is associated with schizophrenia.
Ohtsuki T, et al.
Schizophrenia Research, 101(1-3), 9-16 (2008)
Hemizygous deletion on chromosome 3p26. 1 is associated with heavy smoking among African American subjects in the COPDGene Study.
Begum F, et al.
PLoS ONE, 11(10), e0164134-e0164134 (2016)
Glutamate receptor, metabotropic 7 (GRM7) gene variations and susceptibility to autism: A case-control study.
Noroozi R, et al.
Autism Research : Official Journal of the International Society for Autism Research, 9(11), 1161-1168 (2016)

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