SAB4503838
Anti-phospho-SYK (pTyr348) antibody produced in rabbit
affinity isolated antibody
Synonym(s):
Anti-IMD82, Anti-p72-Syk
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC, WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 72 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pTyr348)
Quality Level
Gene Information
human ... SYK(6850)
Related Categories
General description
Spleen tyrosine kinase (SYK) is a member of the non-receptor tyrosine kinase family. It is usually expressed in epithelial breast tissues and hematopoietic cells.SYK is mapped to human chromosome 9q22.
Immunogen
The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr348.
Immunogen Range: 314-363
Immunogen Range: 314-363
Biochem/physiol Actions
Spleen tyrosine kinase (SYK), as a tumor suppressor gene helps to prevent the development and metastasis of breast cancer cells.It participates in B-cell receptor signaling.This protein helps to phosphorylate the α-tubulin subunits of microtubules.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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wgk
WGK 1
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Genomic and expression profiling identifies the B-cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma
Rinaldi A, et al.
British Journal of Haematology, 132(3), 303-316 (2006)
Novel SYK gene variations and changes in binding sites of miRs in breast cancer patients
Faryal R, et al.
Cancer Biomarkers : Section A of Disease Markers, 16(3), 319-326 (2016)
Syk: a new player in the field of breast cancer
Stewart ZA and Pietenpol JA
Breast Cancer Research, 3(1), 5-7 (2001)
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