SML0235
CDPPB
≥98% (HPLC)
Synonym(s):
3-Cyano-N-1,3-diphenyl-1H-pyrazol-5-yl)benzamide
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About This Item
Empirical Formula (Hill Notation):
C23H16N4O
CAS Number:
Molecular Weight:
364.40
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: ≥5 mg/mL at warmed to 60 °C
storage temp.
2-8°C
SMILES string
O.O=C(Nc1cc(nn1-c2ccccc2)-c3ccccc3)c4cccc(c4)C#N
InChI
1S/C23H16N4O.H2O/c24-16-17-8-7-11-19(14-17)23(28)25-22-15-21(18-9-3-1-4-10-18)26-27(22)20-12-5-2-6-13-20;/h1-15H,(H,25,28);1H2
InChI key
GZHZEGYXLNXEBV-UHFFFAOYSA-N
Application
CDPPB may be used in mGluR5-mediated cell signaling studies.
Biochem/physiol Actions
Activation of metabotropic glutamate 5 receptor by CDPPB enhances the function of NMDA receptor and markers of neuronal plasticity. This improves recognition memory and cognition deficits in schizophrenia.
CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator.
CDPPB is an mGluR5 positive allosteric modulator
Features and Benefits
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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