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Merck
CN

SML0494

VU0361737

≥98% (HPLC)

Synonym(s):

CID-44191096, ML128, N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide

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About This Item

Empirical Formula (Hill Notation):
C13H11ClN2O2
CAS Number:
1161205-04-4
Molecular Weight:
262.69
NACRES:
NA.77
PubChem Substance ID:
329825444
UNSPSC Code:
12352200
MDL number:
MFCD16618402

Key Documents

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Product Name

VU0361737, ≥98% (HPLC)

InChI

1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)

SMILES string

COc1cc(NC(=O)c2ccccn2)ccc1Cl

InChI key

ARYUXFNGXHNNDM-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

film

color

white

solubility

DMSO: 15 mg/mL (clear solution)

storage temp.

2-8°C

Quality Level

100

Related Categories

Biochem/physiol Actions

VU0361737 is an mGluR4-specific positive allosteric modulator (PAM) with greater than 50 fold selectivity over other mGluR subtypes. The EC50 values for human and rat mGlu4 are 240 and 110 nM, respectively, compared to greater than 10 mM for all other mGluRs.
VU0361737 is an mGluR4-specific positive allosteric modulator (PAM).

Features and Benefits

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
092M4618V

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Articles

Glutamate Receptors (G Protein Family)

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