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Merck
CN

SML0803

Sigma-Aldrich

VUF10661

≥98% (HPLC), Chemokine receptor CXCR3 agonist, powder

Synonym(s):

(3S)-N-[(1S)-5-Amino-1-[[(2,2-diphenylethyl)amino]carbonyl]pentyl]-2-(1,4-dioxo-4-phenylbutyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide

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About This Item

Empirical Formula (Hill Notation):
C40H44N4O4
CAS Number:
914291-63-7
Molecular Weight:
644.80
UNSPSC Code:
51111800
NACRES:
NA.77

Key Documents

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Product Name

VUF10661, ≥98% (HPLC)

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

−20°C

Related Categories

Biochem/physiol Actions

VUF10661 is a potent agonist of the chemokine receptor CXCR3.
VUF10661 is a potent agonist of the chemokine receptor CXCR3. VUF10661 induces receptor internalization, recruitment of ?-arrestins and activates Gi proteins with similar potency to endogenous CXCL ligands.

Features and Benefits

This compound is featured on the Chemokine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301,H315,H319,H335,H413

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000151092
0000151091
0000151091
0000151092
0000121490

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Articles

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