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Merck
CN

SML1455

DAA-I acetate salt

≥98% (HPLC)

Synonym(s):

5-L-Isoleucine-2-10-Angiotensin I acetate salt, Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu acetate, RVYIHPFHL acetate, [Des-Asp1-Ile5]angiotensin I, des-Asp-angiotensin I acetate, des-aspartate-angiotensin-I acetate

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About This Item

Empirical Formula (Hill Notation):
C58H84N16O11 · xC2H4O2
CAS Number:
Molecular Weight:
1181.39 (free base basis)
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
film
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Quality Segment

assay

≥98% (HPLC)

form

film

color

colorless

shipped in

wet ice

storage temp.

−20°C

Biochem/physiol Actions

Des-aspartate-angiotensin I (DAA-I) is a nine-amino acid angiotensin peptide and a metabolite of angiotensin DAA-I mediates attenuation of early inflammatory processes and intercellular adhesion molecule-1 (ICAM-1) formation in animal models.
DAA-I (des-aspartate-angiotensin-I) is an agonist on the angiotensin AT1 receptor and releases prostaglandins which mediate its actions. DAA-I administer at doses lesser than Km of metabolizing enzymes antagonize the deleterious actions of angiotensin II. DAA-I appear function in vivo as a physiological antagonist to angiotensin II.
DAA-I (des-aspartate-angiotensin-I) is an agonist on the angiotensin AT1 receptor.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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