SML2046
ARM390
≥98% (HPLC)
Synonym(s):
AR-M 1000390, N,N-Diethyl-4-(phenyl-4-piperidinylidenemethyl)benzamide
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About This Item
Empirical Formula (Hill Notation):
C23H28N2O
CAS Number:
Molecular Weight:
348.48
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
O=C(C1=CC=C(C(C2=CC=CC=C2)=C3CCNCC3)C=C1)N(CC)CC
InChI
1S/C23H28N2O/c1-3-25(4-2)23(26)21-12-10-19(11-13-21)22(18-8-6-5-7-9-18)20-14-16-24-17-15-20/h5-13,24H,3-4,14-17H2,1-2H3
InChI key
SMUGAZNLKPFBSB-UHFFFAOYSA-N
Biochem/physiol Actions
ARM390 in a δ-selective opioid receptor agonist derivative of SNC80. ARM390 leads to very low levels of receptor internalization, and does not induce acute desensitization of analgesic response compared to SNC80. ARM390 preferentially recruits arrestin 3 to the delta opioid receptor in mice.
low-internalizing δ opioid receptor agonist
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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