SML2173
NS3861
≥98% (HPLC)
Synonym(s):
3-(3-Bromo-2-thienyl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene, NS 3861
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About This Item
Empirical Formula (Hill Notation):
C12H14BrNS
CAS Number:
Molecular Weight:
284.22
UNSPSC Code:
12352200
NACRES:
NA.77
Product Name
NS3861, ≥98% (HPLC)
InChI key
ZJCNRVHZJADROC-UHFFFAOYSA-N
SMILES string
BrC1=C(SC=C1)C2=CC(N3C)CCC3C2
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Related Categories
Biochem/physiol Actions
α3β2 heteromeric neuronal nAChRs agonist
NS3861 is a neuronal nicotinic receptor agonist that selectively activates α3 containing nAChRs and it displays higher efficacy at the α3β2 receptor compared with the α3β4 receptor. NS3861 does not activate α4 containing receptors. NS3861 was reported to reverse chronic opioid-induced constipation in vivo.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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