SML2193
Altenusin
≥98% (HPLC)
Synonym(s):
3,4′,5′-Trihydroxy-5-methoxy-2′-methyl[1,1′-biphenyl]-2-carboxylic acid, Alutenusin
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About This Item
Empirical Formula (Hill Notation):
C15H14O6
CAS Number:
Molecular Weight:
290.27
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
biological source
Penicillium sp.
assay
≥98% (HPLC)
form
powder
color
yellow to orange
storage temp.
−20°C
SMILES string
OC1=CC(C2=CC(OC)=CC(O)=C2C(O)=O)=C(C)C=C1O
InChI
1S/C15H14O6/c1-8-5-13(16)14(17)7-11(8)12-6-9(20-2)3-4-10(12)15(18)21-19/h3-7,16-17,19H,1-2H3
InChI key
GWGIZSANXIQQQR-UHFFFAOYSA-N
Biochem/physiol Actions
Altenusin, a non-steroidal fungal metabolite, is a potent and selective agonist of Farnesoid X receptor (FXR) that protects mice from high-fat diet induced obesity. Also it decreases blood glucose level, serum insulin level, and reduces lipid droplets accumulation. Altenusin inhibits trypanothione reductase from Trypanosoma cruzi.
potent and selective agonist of Farnesoid X receptor (FXR)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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