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Merck
CN

SML2307

Lodoxamide

≥98% (HPLC)

Synonym(s):

2,2′-[(2-Chloro-5-cyano-1,3-phenylene)diimino]bis-2-oxoacetic acid

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About This Item

Empirical Formula (Hill Notation):
C11H6ClN3O6
CAS Number:
Molecular Weight:
311.63
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to very dark brown

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

Clc1c(cc(cc1NC(=O)C(=O)O)C#N)NC(=O)C(=O)O

InChI

1S/C11H6ClN3O6/c12-7-5(14-8(16)10(18)19)1-4(3-13)2-6(7)15-9(17)11(20)21/h1-2H,(H,14,16)(H,15,17)(H,18,19)(H,20,21)

InChI key

RVGLGHVJXCETIO-UHFFFAOYSA-N

Biochem/physiol Actions

Lodoxamide Tromethamine is a potent agonist of GPR35 in both human and rat, and an antiallergic mast cell stabilizer used clinically in the UK for treatment of allergic conjunctivitis.
potent agonist of GPR35 in both human and rat, and an antiallergic mast cell stabilizer


Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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