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SML2592

Arteether

≥95% (HPLC)

Synonym(s):

β-Arteether, (+)-Arteether, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, Dihydroartemisinin ethyl ether

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About This Item

Empirical Formula (Hill Notation):
C17H28O5
CAS Number:
75887-54-6
Molecular Weight:
312.40
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
MFCD00869355
Assay:
≥95% (HPLC)
Form:
powder
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assay

≥95% (HPLC)

form

powder

optical activity

[α]/D +148 to +165°, c = 1 in chloroform-d

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O1OC2(O[C@H]3O[C@@H]([C@@H]([C@H]4[C@]31[C@H]([C@@H](CC4)C)CC2)C)OCC)C

InChI

1S/C17H28O5/c1-5-18-14-11(3)13-7-6-10(2)12-8-9-16(4)20-15(19-14)17(12,13)22-21-16/h10-15H,5-9H2,1-4H3/t10-,11-,12+,13+,14+,15-,16?,17-/m1/s1

InChI key

NLYNIRQVMRLPIQ-BVCZABNKSA-N

Biochem/physiol Actions

Antimalarial artemisinin derivative
Arteether is a semisynthetic artemisinin derivative with antimalarial activity. It has been used for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria, and has also been shown to have anticancer activity.

pictograms

FlameHealth hazard
GHS02,GHS08

signalword

Danger

Hazard Classifications

Org. Perox. D - Repr. 2

Storage Class

5.2 - Organic peroxides and self-reacting hazardous materials

flash_point_f

No data available

flash_point_c

No data available

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