SML2596
Sphynolactone-7
≥98% (HPLC)
Synonym(s):
4-Methyl-5-oxo-2,5-dihydrofuran-2-yl 4-(4-butoxyphenylsulfonyl)piperazine-1-carboxylate, SPL-7, SPL7
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About This Item
Empirical Formula (Hill Notation):
C20H26N2O7S
CAS Number:
Molecular Weight:
438.49
UNSPSC Code:
12352200
NACRES:
NA.77
form
powder
InChI key
GGAPQPVAXJSNFU-UHFFFAOYSA-N
SMILES string
CCCCOC1=CC=C(S(N2CCN(C(OC3C=C(C)C(O3)=O)=O)CC2)(=O)=O)C=C1
assay
≥98% (HPLC)
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
Related Categories
Biochem/physiol Actions
Highly potent & selective strigolactone receptor ShHTL7 agonist. Femto-/Pico-molar germination stimulant of the parasitic plant Striga hermonthica/Orobanche minor.
Sphynolactone-7 (SPL-7) is an active site-targeting, highly potent and selective strigolactone receptor ShHTL7 agonist (YLG competitive binding IC50 = 310 nM/ShHTL7, 1.2 μM/ShHTL8, >7.0 μM/ShHTL2-6, ShHTL9-11, AtD14) that acts as a seeds germination stimulant with femtomolar- and picomolar-level potency, respectively, toward the parasitic plants Striga hermonthica ecotypes and Orobanche minor, while exhibiting no Arabidopsis-stimulatory efficacy.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Daisuke Uraguchi et al.
Science (New York, N.Y.), 362(6420), 1301-1305 (2018-12-14)
The parasitic plant Striga hermonthica has been causing devastating damage to the crop production in Africa. Because Striga requires host-generated strigolactones to germinate, the identification of selective and potent strigolactone agonists could help control these noxious weeds. We developed a
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