SML2753
UCSF4226
≥98% (HPLC)
Synonym(s):
N-[(2-bromo-5-?methoxyphenyl)methyl]-3-?pyridinamine, ZINC128734226
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About This Item
Empirical Formula (Hill Notation):
C13H13BrN2O
CAS Number:
Molecular Weight:
293.16
UNSPSC Code:
12352200
NACRES:
NA.77
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Related Categories
Biochem/physiol Actions
UCSF4226 (ZINC128734226) is brain permeable, potent and selective agonist of human melatonin hMT2 receptor.
brain permeable, potent and selective agonist of human melatonin hMT2 receptor
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Reed M Stein et al.
Nature, 579(7800), 609-614 (2020-02-11)
The neuromodulator melatonin synchronizes circadian rhythms and related physiological functions through the actions of two G-protein-coupled receptors: MT1 and MT2. Circadian release of melatonin at night from the pineal gland activates melatonin receptors in the suprachiasmatic nucleus of the hypothalamus
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