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SML3317

Losartan

Name: Losartan
Brand: SIGMA

≥98% (HPLC), powder, angiotensin II receptor type 1 (AT1) antagonist

Synonym(s):

1-[1-[[2′-(2H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-butyl-4-chloro-1H-imidazol-5-yl]methanol, 2-Butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)-1,1′-biphenyl-4-yl]methyl]-1H-imidazole-5-methanol, 2-Butyl-4-chloro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, DUP 89

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About This Item

Empirical Formula (Hill Notation):

C₂₂H₂₃ClN₆O

CAS Number:

114798-26-4

Molecular Weight:

422.91

NACRES:

NA.77

UNSPSC Code:

12352200

MDL number:

MFCD19686114

Assay:

≥98% (HPLC)

Form:

powder

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Properties

Product Name

Losartan, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

OCC1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=C(C4=NNN=N4)C=CC=C3)C=C2

InChI

1S/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)

InChI key

PSIFNNKUMBGKDQ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Losartan is an orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist. Losartan is used for treatment of hypertension.

Orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist

pictograms

GHS08,GHS07

signalword

Danger

hcodes

H317,H360FD,H362

pcodes

P202 - P260 - P263 - P280 - P302 + P352 - P308 + P313

Hazard Classifications

Lact. - Repr. 1B - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c