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Merck
CN

SML3964

Methylprednisolone acetate

≥98% (HPLC)

Synonym(s):

(6α,11β)-21-(Acetyloxy)-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione acetate, 11β,17α,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate, 21-Acetoxy-11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione acetate, 6-Methylprednisolone acetate, Depo-Medro acetatel

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About This Item

Empirical Formula (Hill Notation):
C24H32O6
CAS Number:
Molecular Weight:
416.51
UNSPSC Code:
12352200
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D 85 to 105°, c = 0.5 in chloroform-d

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

Long-acting anti-inflammatory corticosteroid that suppresses lymphocytes-mediated immunologic responses.



Methylprednisolone acetate (Depo-Medrol) is a long-acting anti-inflammatory corticosteroid that suppresses lymphocytes-mediated immunologic responses. 6-Methylprednisolone acetate binds to intracellular glucocorticoid receptors and inhibits promoter domains of pro-inflammatory genes and hinders secretion of inflammatory cytokines. It effectively treats multiple ailments such as rheumatic and autoimmune diseases, leukemia, multiple myeloma, and Hodgkin’s and non-Hodgkin’s lymphoma symptoms along with other drugs. MPA improves COVID-19 pneumonia prognosis.


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pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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