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Merck
CN

SML3994

Sigma-Aldrich

BODIPY TR-X NHS Ester

≥95% (HPLC)

Synonym(s):

(T-4)-[N-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-2-[4-[5-[[5-(2-thienyl)-2H-pyrrol-2-ylidene-κN]methyl]-1H-pyrrol-2-yl-κN]phenoxy]acetamidato]difluoroboron, 6-(((4-(4,4-Difluoro-5-(2-thienyl)-4-bora-3a,4a-diaza-s-indacene-3-yl)phenoxy)acetyl)amino)hexanoic acid succinimidyl ester, BODIPY TR-X, BODIPY TR-X NHS, BODIPY TR-X, SE

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Quality Level

100

Assay

≥95% (HPLC)

form

powder

color

, Red To very dark purple

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

O=C(CCCCCNC(COC1=CC=C(C2=CC=C3C=C4C=CC(C5=CC=CS5)=[N]4[B+3]([F-])([N-]32)[F-])C=C1)=O)ON6C(CCC6=O)=O

Related Categories

Biochem/physiol Actions

Amine reactive, red luminous fluorescent labeling reagent that can be used to tag antibodies, proteins, peptides, and nucleic acids.

BODIPY TR-X NHS Ester is a versatile, amine-sensitive red fluorescent labeling reagent useful to tag antibodies, proteins, peptides, and nucleic acids. BODIPY TR dyes, also called boron-dipyrromethene tetramethylrhodamine, are known for their exceptional photophysical properties, including high fluorescence quality and photostability, with wide spectral tuning. BODIPY TR has a narrow absorption range (~ 500-550 nm) and a broader emission range (~ 580-640 nm) for multi-color cell labeling. BODIPY TR-X offers an extended excited-state lifetime for fluorescence polarization assays and significant two-photon excitation capability. BODIPY TR-X NHS Ester is a valuable tool for fluorescence microscopy, flow cytometry, and IHC applications.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000393397
0000379191
0000379191
0000393397

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Łukasz Bujak et al.
Nanoscale, 9(4), 1511-1519 (2017-01-10)
Förster resonant energy transfer (FRET) is a nonradiative process by which the energy of light absorbed by a donor molecule is transferred to an acceptor molecule over a distance of several nanometers. FRET plays a crucial role in photosynthesis and
Karen Martin et al.
Proteomics, 2(5), 499-512 (2002-05-03)
A two-color fluorescence detection method is described based upon covalently coupling the succinimidyl ester of BODIPY TR-X dye to proteins immobilized on polyvinylidene difluoride membranes, followed by detection of target proteins using the fluorogenic, precipitating substrate ELF 39-phosphate in combination
Highly potent and selective fluorescent antagonists of the human adenosine A? receptor based on the 1,2,4-triazolo[4,3-a]quinoxalin-1-one scaffold
Journal of Medicinal Chemistry, 55(4), 1771-1782 (2012)

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