SML4026
ZH8651 hydrochloride
≥98% (HPLC)
Synonym(s):
2-(4-Bromophenyl)ethan-1-amine hydrochloride, 4-Bromobenzene-ethanamine hydrochloride, 4-Bromophenethylamine hydrochloride, p-Bromophenethylamine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C8H10BrN ·HCl
CAS Number:
Molecular Weight:
236.54
UNSPSC Code:
12352200
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
BrC1=CC=C(C=C1)CCN.Cl
InChI
1S/C8H10BrN.ClH/c9-8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H
InChI key
ZHAWIPAHUYMLDV-UHFFFAOYSA-N
Biochem/physiol Actions
Orally available, potent, and selective agonist of Trace amine-associated receptor 1 (TAAR1); dual activator of Gs and Gq in mTAAR1/hTAAR1.
ZH8651 is an orally available, potent, and selective agonist of Trace amine-associated receptor 1 (TAAR1). ZH8651 is dual activator of Gs and Gq in mTAAR1/hTAAR1 (EC50 = 9,85 nM (Gs), 66.5 nM Gq). ZH8651 alleviates MK-801-induced schizophrenia-like phenotypes without inducing catalepsy in mice.
ZH8651 is an orally available, potent, and selective agonist of Trace amine-associated receptor 1 (TAAR1). ZH8651 is dual activator of Gs and Gq in mTAAR1/hTAAR1 (EC50 = 9,85 nM (Gs), 66.5 nM Gq). ZH8651 alleviates MK-801-induced schizophrenia-like phenotypes without inducing catalepsy in mice.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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