biological source
human
recombinant
expressed in human cells
Assay
≥95% (SDS-PAGE)
form
lyophilized
mol wt
(17 and 27 kDa, monomer, glycosylated)
packaging
pkg of 10 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... FGF4(2249)
General description
The FGF4 (fibroblast growth factor 4) gene is mapped to human chromosome 11q13.3. It is expressed during early embryonic development. In adults, it is strongly expressed in the testis.
Biochem/physiol Actions
FGF4 (fibroblast growth factor 4) helps in preserving the self-renewal capability of normal stem cells. The encoded protein has the ability to interact with FGFR1c (FGF receptor 1c) and FGFR2c. It also binds to FGFR3c and FGFR4, but to a lesser extent. FGFR4 is also required for cellular differentiation, morphogenesis and proliferation. It modulates proliferation and differentiation of normal stem cells, progenitor cells and cancer cells.
Physical form
Lyophilized from a PBS solution.
Preparation Note
Centrifuge the vial prior to opening.
Reconstitution
Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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