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T0195

α-Bungarotoxin-tetramethylrhodamine

from Bungarus multicinctus (Formosan Banded Krait), Nicotinic acetylcholine receptor antagonist

Synonym(s):

TMR-α-BTX

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About This Item

UNSPSC Code:
12352116
NACRES:
NA.77
MDL number:
MFCD00286495
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Product Name

α-Bungarotoxin-tetramethylrhodamine from Bungarus multicinctus (Formosan Banded Krait),

mol wt

~8,500

Quality Segment

100

color

red

solubility

H2O: soluble

storage temp.

−20°C

Application

α-Bungarotoxin-tetramethylrhodamine from Bungarus multicinctus (Formosan Banded Krait) has been used in immunofluorescence staining (1:200) for identification of neuromuscular junction in experimental models. It has also been used to block muscle contraction in myotome cells.
α-Bungarotoxin-tetramethylrhodamine from Bungarus multicinctus was used at a dilution of 1:220 to identify the distribution of nicotinic acetylcholine receptors at neuromuscular junctions of longitudinal sections of rat gastrocnemius muscle.

Biochem/physiol Actions

α-Bungarotoxin is a high-affinity antagonist for nicotinic acetylcholine receptors (AChRs) from muscle but not the neurons. Labeling α-Bungarotoxin with tetramethylrhodamine enables the detection of bungarotoxin-binding receptors at neuromuscular junctions.
Useful for detecting the distribution of nicotinic acetylcholine receptors at neuromuscular junctions.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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