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T3128

Trizma® maleate

Synonym(s):

TRIS maleate salt, Tris(hydroxymethyl)aminomethane maleate salt, Tromethamine maleate salt

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About This Item

Linear Formula:
NH2C(CH2OH)3 · C4H4O4
CAS Number:
72200-76-1
Molecular Weight:
237.21
NACRES:
NA.25
PubChem Substance ID:
24900108
UNSPSC Code:
12161700
EC Number:
276-455-6
MDL number:
MFCD00082442
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assay

≥99.5% NaOH basis (anhydrous, titration)

Quality Level

200

form

crystalline powder

color

colorless

solubility

water: 500 mg/mL, clear, colorless

SMILES string

NC(CO)(CO)CO.OC(=O)\C=C/C(O)=O

InChI

1S/C4H11NO3.C4H4O4/c5-4(1-6,2-7)3-8;5-3(6)1-2-4(7)8/h6-8H,1-3,5H2;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

HTMWOUBCEZXSHN-BTJKTKAUSA-N

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Application

Trizma® maleate has been used:
  • in the rehydration of sputum cytospin samples for immunocytochemical analysis
  • in the incubation of spinal cords sections prior to nucleoside diphosphatase assay
  • as a component of alkaline phosphate (AP) staining for embryonic stem cells

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 1 Oral

target_organs

Central nervous system

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Certificates of Analysis (COA)

Lot/Batch Number
0000548065
0000548064
0000548065
0000548064
0000525790

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Putative porcine embryonic stem cell lines derived from aggregated four-celled cloned embryos produced by oocyte bisection cloning
Siriboon C, et al.
Testing, 10(2), e0118165-e0118165 (2015)
Nitrosative stress, heme oxygenase-1 expression and airway inflammation during severe exacerbations of COPD
Tsoumakidou M, et al.
Chest, 127(6), 1911-1918 (2005)
CD4 microglial expression correlates with spontaneous clinical improvement in the acute Lewis rat EAE model
Almolda B, et al.
Journal of Neuroimmunology, 209(1-2), 65-80 (2009)
Abeer Maher Fayyad et al.
International journal of molecular sciences, 20(7) (2019-04-04)
Obesity is a major risk for diabetes. Brown adipose tissue (BAT) mediates production of heat while white adipose tissue (WAT) function in the storage of fat. Roles of BAT in the treatment of obesity and related disorders warrants more investigation.
Greg Holmes et al.
Development (Cambridge, England), 145(19) (2018-09-20)
Midface dysgenesis is a feature of more than 200 genetic conditions in which upper airway anomalies frequently cause respiratory distress, but its etiology is poorly understood. Mouse models of Apert and Crouzon craniosynostosis syndromes exhibit midface dysgenesis similar to the
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Global Trade Item Number

SKUGTIN
T3128-50G04061837343759
T3128-250G04061837343742
T3128-100G04061837343735

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