V4390
VUF 8430 dihydrobromide
≥97% (NMR)
Synonym(s):
2-[(Aminoiminomethyl)amino]ethyl carbamimidothioic acid ester, S-(2-guanidylethyl)-isothiourea
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About This Item
Empirical Formula (Hill Notation):
C4H11N5S· 2HBr
CAS Number:
Molecular Weight:
323.05
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥97% (NMR)
Form:
solid
Storage condition:
desiccated
Quality Segment
assay
≥97% (NMR)
form
solid
storage condition
desiccated
solubility
deionized water: 24 mg/mL
storage temp.
room temp
SMILES string
Br.Br.NC(=N)NCCSC(N)=N
InChI
1S/C4H11N5S.2BrH/c5-3(6)9-1-2-10-4(7)8;;/h1-2H2,(H3,7,8)(H4,5,6,9);2*1H
InChI key
GPWJSTKHQMIXCA-UHFFFAOYSA-N
Biochem/physiol Actions
VUF 8430 dihydrobromide is a potent histamine H4 receptor agonist, with a 33-fold selectivity over the histamine H3 receptor and negligible affinity for the other histamine receptor.
Features and Benefits
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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