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About This Item
Empirical Formula (Hill Notation):
C18H24O5
CAS Number:
Molecular Weight:
320.38
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (TLC)
Form:
powder
Product Name
Zearalanone,
sterility
non-sterile
Quality Segment
assay
≥98% (TLC)
form
powder
solubility
methanol: 9.80-10.20 mg/mL, clear, colorless
shipped in
ambient
storage temp.
−20°C
SMILES string
C[C@H]1CCCC(=O)CCCCCc2cc(O)cc(O)c2C(=O)O1
InChI
1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,20-21H,2-9H2,1H3/t12-/m0/s1
InChI key
APJDQUGPCJRQRJ-LBPRGKRZSA-N
Gene Information
rat ... Ar(24208)
General description
Zearalanone (ZEA) or F-2 toxin, a nonsteroidal estrogenic mycotoxin is produced by various Fusarium species. Fusarium graminearum is considered as the primary producer of zearalanone. It is usually seen in moldy hay, high-moisture corn, corn infected before harvest etc.
Application
Zearalanone has been used:
- as mycotoxin to study its effects on the histology of ovaries in pre-pubertal bitches
- as a mycotoxin to investigate its influence on selected immunological, haematological and biochemical indexes in bitches
- as a standard to develop calibration curves in order to study its effects on progesterone and 17β-estradiol concentrations in peripheral blood and body weights of pre-pubertal female Beagle dogs
- as a standard to develop calibration curves to study its level of intoxication in women with neoplastic lesions in the reproductive tract
Biochem/physiol Actions
Zearalanone is believed to cause vulvovaginitis and estrogenic responses in swine.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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