All Photos(1)

Documents

COO/COA

12024AST

Astec^® CHIROBIOTIC^® T Chiral HPLC Column

Name: Astec<SUP>®</SUP> CHIROBIOTIC<SUP>®</SUP> T Chiral HPLC Column
Brand: SUPELCO

5 μm particle size, L × I.D. 25 cm × 4.6 mm

Sign Into View Organizational & Contract Pricing

All Photos(1)

eCl@ss:

32110501

NACRES:

SB.52

material

stainless steel column

Quality Level

100

Agency

suitable for USP L63

description

HPLC column

product line

Astec^®

packaging

pkg of 1 ea

manufacturer/tradename

Astec^®

parameter

0-45 °C temperature
241 bar pressure (3500 psi)

technique(s)

HPLC: suitable
LC/MS: suitable

L × I.D.

25 cm × 4.6 mm

matrix

High-purity silica gel particle platform
fully porous particle

matrix active group

teicoplanin glycopeptide phase

particle size

5 μm

pore size

100 Å

operating pH range

3.8-6.8

separation technique

chiral

Looking for similar products? Visit Product Comparison Guide

Related Categories

Exclusive Savings

HPLC Columns

General description

CHIROBIOTIC^® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. Separations normally obtained on a chiral crown ether or ligand exchange-type CSPs are also possible on the CHIROBIOTIC^® T and T2, but in much simpler mobile phases, like water-alcohol. In addition, all of the known beta-blockers (amino alcohols), and dihydrocoumarins have been resolved. CHIROBIOTIC^® T and T2 differ in their bonding chemistry and the pore size of the support particle, giving them different selectivity and preparative capacity.

Bonded phase: Teicoplanin
Operating pH range: 3.8 - 6.8
Particle diameter: 5, 10 or 16 μm
Pore size: 100 Å (CHIROBIOTIC^® T) or 200 Å (CHIROBIOTIC^® T2)

CHIROBIOTIC FAQs
CHIROBIOTIC Reference Bibliography
Chiral Product Literature

Recommended products

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

Application

Product No.

Description

Pricing

related product

Product No.

Description

Pricing

12100AST

Astec^® CHIROBIOTIC^® T Chiral HPLC Guard Column, Cartridge, 5 μm particle size, L × I.D. 2 cm × 4 mm

21150AST

Supelguard^™ Guard Cartridge Holder, Stand-Alone (Swivel-type), for use with Supelguard cartridges (2 cm L. x 2 to 4.6 mm I.D.)

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

How to Find the Product Number

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503

Product Number

25G

Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

How to Find a Lot/Batch Number for COA

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').
For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').
For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Chiral separation of thiazide diuretics by HPLC on Chiralcel OD-RH, Chiralcel OJ-R and Chirobiotic-T phases.

Balázs Visegrády et al.

Journal of biochemical and biophysical methods, 53(1-3), 15-24 (2002-10-31)

This contribution deals with comparative studies on the chiral separation of thiazide diuretics using cellulose tris(3,5-dimethylphenylcarbamate) (Chiralcel OD-RH), cellulose tris(4-methylbenzoate) (Chiralcel OJ-R) and teicoplanin (Chirobiotic T) phases. All columns showed good chiral recognition ability for this class of compounds. Out

Design and synthesis of a library of tertiary amides: evaluation as mimetics of the melanocortins' active core.

Felikss Mutulis et al.

Bioorganic & medicinal chemistry, 15(17), 5787-5810 (2007-07-10)

Two hundred and ten tertiary amides were prepared on solid phase. Diamines were coupled to activated carboxylated Wang polymer, and the polymeric substituted benzyloxycarbonyl protected diamines obtained were reacted with aldehydes or ketones in trimethyl orthoformate giving resin attached Schiff

Insights into the retention mechanism of neutral organic compounds on polar chemically bonded stationary phases in reversed-phase liquid chromatography.

Zahid Ali et al.

Journal of chromatography. A, 1052(1-2), 199-204 (2004-11-06)

The solvation parameter model is used to characterize the retention properties of a 3-aminopropylsiloxane-bonded (Alltima amino), three 3-cyanopropylsiloxane-bonded (Ultrasphere CN, Ultremex-CN and Zorbax SB-CN), a spacer bonded propanediol (LiChrospher DIOL) and a multifunctional macrocyclic glycopeptide (Chirobiotic T) silica-based stationary phases

Syntheses of racemic and non-racemic silicon- and germanium-containing a-amino acids of the formula type H2NCH(CH2ElR3)COOH (El=Si, Ge; R=organyl) and incorporation of d-H2NCH(CH2SiMe3)COOH and d-H2NCH(CH2GeMe3)COOH into biologically active decapeptides: a study on C/Si/Ge bioisosterism

Merget, Markus, et al.

Journal of Organometallic Chemistry, 628 (2), 183-194 (2001)

Methotrexate determination in pharmaceuticals by enantioselective HPLC.

D Abd el-Hady et al.

Journal of pharmaceutical and biomedical analysis, 37(5), 919-925 (2005-05-03)

A simple, sensitive and selective high performance liquid chromatographic method with UV detection for the chiral separation of racemic methotrexate (rac-Mtx) and enantiomeric purity of L-methotrexate in pharmaceutical formulations was developed and validated. The chiral separation was optimized studying both

View All Related Papers

Chromatograms

HPLC Analysis of t-BOC-Tyrosine Enantiomers on Astec^® CHIROBIOTIC^® T

application for HPLC

HPLC Analysis of t-BOC-Alanine Enantiomers on Astec^® CHIROBIOTIC^® T

application for HPLC

HPLC Analysis of Butorphanol Enantiomers on Astec^® CHIROBIOTIC^® T

application for HPLC

HPLC Analysis of FMOC-Isoleucine Enantiomers on Astec^® CHIROBIOTIC^® T

application for HPLCShow More

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Documents

Astec® CHIROBIOTIC® T Chiral HPLC Column

5 μm particle size, L × I.D. 25 cm × 4.6 mm

Properties

material

Quality Level

Agency

description

product line

packaging

manufacturer/tradename

parameter

technique(s)

L × I.D.

matrix

matrix active group

particle size

pore size

operating pH range

separation technique

Related Categories

Description

General description

Recommended products

Legal Information

Related Products

Application

related product

Safety Information

Storage Class Code

WGK

Flash Point(F)

Astec^® CHIROBIOTIC^® T Chiral HPLC Column