14023AST
Astec® CHIROBIOTIC® TAG Chiral (5 μm) HPLC Columns
L × I.D. 15 cm × 4.6 mm, HPLC Column
Synonym(s):
Chirobiotic TAG Chiral Chromatography Column
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Product Name
Astec® CHIROBIOTIC® TAG Chiral HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
material
stainless steel column
agency
suitable for USP L63
description
HPLC column
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-45 °C temperature
241 bar pressure (3500 psi)
technique(s)
HPLC: suitable
LC/MS: suitable
L × I.D.
15 cm × 4.6 mm
matrix
High-purity silica gel particle platform
fully porous particle
matrix active group
teicoplanin aglycone phase
particle size
5 μm
pore size
100 Å
operating pH range
3.0-6.8
separation technique
chiral
Quality Level
Looking for similar products? Visit Product Comparison Guide
Related Categories
Application
- High-performance liquid chromatographic enantioseparation of 2-aminomono- and dihydroxycyclopentanecarboxylic and 2-aminodihydroxycyclohexanecarboxylic acids on macrocyclic glycopeptide-based phases.: This study emphasizes the effectiveness of the Astec® CHIROBIOTIC® TAG Chiral HPLC Column in the enantioseparation of complex cyclic amino acids. The methodology detailed provides profound insights into the chirality aspects of biochemical molecules, which is crucial for the synthesis of novel pharmaceutical agents and the study of biochemical pathways. This research supports analytical chemists in academia focused on developing chiral analytical methods and advancing chemical synthesis (Berkecz et al., 2009).
General description
The removal of three carbohydrate moieties gives CHIROBIOTIC® TAG complementary selectivity to CHIROBIOTIC® T. Resolution is enhanced toward many of the amino acids, α, β, γ and cyclic, and especially sulfur-containing methionine, histidine and cysteine. A number of neutral molecules like the oxazolidinones, hydantoins and diazepines have shown enhanced resolution and, more remarkably, in the single solvents like methanol, ethanol and acetonitrile. Some acidic molecules have also shown increased selectivity.
- Bonded phase: Teicoplanin aglycone
- Operating pH range: 3.0 - 6.8
- Particle diameter: 5, 10 or 16 μm
- Pore size: 100 Å
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Chemoenzymatic preparation of enantiopure l-benzofuranyl- and l-benzo[b]thiophenyl alanines
Podea, Paula Veronica, et al.
Tetrahedron Asymmetry, 19 (4), 500-511 (2008)
Julia Koidl et al.
Journal of biochemical and biophysical methods, 70(6), 1254-1260 (2007-11-06)
This paper deals with the chiral separation of triiodothyronine (T3) and thyroxine (T4) by HPLC and micro-HPLC. The separation of T3 and T4 is of great pharmaceutical and clinical interest, since the enantiomers exhibit different pharmacological activities. The HPLC measurements
High performance liquid chromatography?tandem mass spectrometry (HPLC/MS/MS) assay for chiral separation of lactic acid enantiomers in urine using a teicoplanin based stationary phase
Norton, Dean, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 850 (1-2), 190-198 (2007)
Matthias Bechtold et al.
Journal of chromatography. A, 1154(1-2), 277-286 (2007-04-24)
Silica-bonded teicoplanin aglycone allows enantioseparation of amino acids by reversed-phase liquid chromatography with a low organic solvent content. However, a reversible change in the adsorption behavior leading to a retention time shift (RTS) was observed when a preparative scale column
Robert J Steffeck et al.
Journal of chromatography. A, 983(1-2), 91-100 (2003-02-06)
Ion-exclusion chromatography is a well established technique for the analysis of achiral ionic species, but it has rarely been applied to chiral analytes. In this paper enantioselective ion-exclusion separations were developed on two commercially available HPLC phases: Chirobiotic TAG, based
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service