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About This Item
eCl@ss:
32110501
UNSPSC Code:
41115700
NACRES:
SB.52
L × i.d.:
25 cm × 4.6 mm
Particle size:
5 μm
Matrix active group:
C8 (octyl) phase
Pore size:
100 Å
Matrix:
octyl, fully porous particle
Product Name
LiChrosorb® RP-8 HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
material
stainless steel column
Quality Level
agency
suitable for USP L7
product line
LiChrosorb®
feature
endcapped: no
manufacturer/tradename
LiChrosorb®
packaging
1 ea of
extent of labeling
9.5% Carbon loading
parameter
≤70 °C temp. range, 400 bar pressure (5801 psi)
technique(s)
HPLC: suitable
L × I.D.
25 cm × 4.6 mm
surface area
300 m2/g
matrix
octyl, fully porous particle
matrix active group
C8 (octyl) phase
particle size
5 μm
pore size
100 Å
operating pH
2-7.5
separation technique
reversed phase
General description
LiChrosorb® RP-8 HPLC column is used for the separation of neutral, acidic and weakly basic compounds.
Application
- Determination of amphotericin B, liposomal amphotericin B, and amphotericin B colloidal dispersion in plasma by high-performance liquid chromatography.: Utilizing the LiChrospher® RP-8 HPLC Column, this study develops a method for analyzing various formulations of amphotericin B in plasma, crucial for monitoring therapeutic levels and preventing toxicity in patients undergoing antifungal treatment (Egger et al., 2001).
- Determination of doxorubicin and metabolites in murine specimens by high-performance liquid chromatography.: This research demonstrates the application of the LiChrospher® RP-8 HPLC Column in the quantification of doxorubicin and its metabolites, enhancing the understanding of its pharmacokinetics and aiding in the optimization of cancer treatment regimens (van Asperen et al., 1998).
- Determination of glibenclamide in human plasma by solid-phase extraction and high-performance liquid chromatography.: Employing the LiChrospher® RP-8 HPLC Column, this method provides accurate and reliable quantification of glibenclamide, a critical component in managing diabetes mellitus (Valdes Santurio and Gonzalez Porto, 1996).
- Simultaneous determination of ampicillin and metampicillin in biological fluids using high-performance liquid chromatography with column switching.: Highlighting the versatility of the LiChrospher® RP-8 HPLC Column, this study develops a technique for the simultaneous determination of ampicillin and its prodrug, metampicillin, crucial for effective antibiotic therapy monitoring (Lee et al., 1995).
Legal Information
LiChrosorb is a registered trademark of Merck KGaA, Darmstadt, Germany
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 54953-U | 04061833516102 |