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Supelco

Supel™ Swift HLB SPE Tubes

weight 30 mg (bed), volume 1 mL, pk of 108 ea

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description

detection: MS friendly

Quality Level

100

product line

Supel™

packaging

pk of 108 ea

technique(s)

solid phase extraction (SPE): suitable

surface area

425-500 m2/g

volume

1 mL

weight

30 mg (bed)

particle size

40-75 μm (>90%)

pore size

80-210 Å pore size

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General description

Supel™ Swift HLB is a co-polymer solid phase extraction (SPE) phase composed of both hydrophilic and lipophilic functional groups. This phase is ideal for extracting a broad range of compounds from aqueous samples, including food and environmental samples, as well as biological samples (eg. serum and plasma). Because of the hydrophilic and lipophilic balanced (HLB) property, the polymer material can selectively retain a wide range of compounds with different polarities and LogP values. Traditional HLB SPE uses a five-step process for sample preparation that normally includes the conditioning of sorbents with an organic solvent followed by an equilibration step to return sorbents to sample loading conditions. The product design allows for direct sample loading onto the sorbent bed, thereby eliminating conditioning of the cartridge. This product feature can both save time and simplify sample preparation, which may also serve to reduce sample processing errors.

Legal Information

Supel is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Articles

Supel™ Swift HLB SPE Cartridges ‒ Solid Phase Extraction (SPE) Made Easy

Supel™ Swift HLB SPE is a polymeric sorbent with lipophilic and hydrophilic functional groups used for solid phase extraction of a wide range of analytes with different polarities. It saves time, offers faster flow rates, and minimum signal enhancement/suppression.

Workflow for the Analysis of Polysorbate 80 in Erbitux® Formulation

A complete reversed phase HPLC-ELSD workflow, including sample preparation for the analysis of Polysorbate 80 in a monoclonal antibody formulation.

Simplified LC-MS/MS Method for Glyphosate, AMPA, and Glufosinate in Oat-Based Cereals

A simplified LC-MS/MS method to determine glyphosate and related compounds using a Supel™ Carbon LC U/HPLC column for stability under higher pH conditions and sufficient retention for the polar analytes in the presence of methanol as an extraction solvent.

LC-MS Analysis of Serum for a Wide Analyte Range Using a Novel HLB SPE Phase

Analysis of 20 pharmaceutical compounds in calf serum using Supel™ Swift HLB SPE cartridge for cleanup and LC-MS determination and another commercially available HLB cartridge for comparison.

Related Content

Solid Phase Extraction (SPE)

Solid phase extraction purifies samples for chromatographic analysis, improving data quality and protecting analytical columns.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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