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About This Item
NACRES:
SB.52
UNSPSC Code:
41115709
Particle size:
2.7 μm
Matrix active group:
bonding phase, Diphenyl (diphenylmethyl)
Pore size:
1000 Å pore size
Matrix:
Fused-Core® particle platform
agency
suitable for USP L11
feature
endcapped
extent of labeling
1.0% loading
column L × I.D.
5 cm × 1.5 mm
surface area
22 m2/g
matrix
Fused-Core® particle platform
matrix active group
bonding phase, Diphenyl (diphenylmethyl)
particle size
2.7 μm
pore size
1000 Å pore size
operating pH range
2-9
Quality Level
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General description
BIOshell™ IgG 1000 Å Diphenyl is a high-speed, high-performance liquid chromatography column based on a new wide-pore (1000 Å) Fused-Core® particle design. The particle provides a thin porous shell of high-purity silica surrounding a solid silica core. This particle design exhibits very high column efficiency due to the shallow diffusion paths in the 0.5 μm thin porous shell and the small overall particle size of 2.7 μm. The densely bonded, extensively endcapped diphenylmethyl bonded phase of BIOshell™ IgG 1000 Å Diphenyl provides a stable, reversed-phase packing that can be used for separating high molecular weight compounds, such as proteins.
Application
Analysis Note
Target analytes include: monoclonal antibodies, antibody-drug conjugates, antibody fragments and large proteins with molecular weights up to 500 kDa.
Legal Information
BIOshell is a trademark of Sigma-Aldrich Co. LLC
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.
Regulatory Information
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