58978
SUPELCOSIL™ LC-18-DB (3 µm) HPLC Columns
L × I.D. 3.3 cm × 4.6 mm, HPLC Column
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
NB.21
L × i.d.:
3.3 cm × 4.6 mm
Particle size:
3 μm
Matrix active group:
C18 (octadecyl) phase
Pore size:
120 Å
Matrix:
silica gel, spherical particle platform
Product Name
SUPELCOSIL™ LC-18-DB HPLC Column, 3 μm particle size, L × I.D. 3.3 cm × 4.6 mm
agency
suitable for USP L1
Quality Level
feature
endcapped
manufacturer/tradename
SUPELCOSIL™
extent of labeling
11.0% Carbon loading
parameter
0-70 °C temperature, 400 bar pressure (5801 psi)
technique(s)
HPLC: suitable
L × I.D.
3.3 cm × 4.6 mm
surface area
170 m2/g
surface coverage
surface coverage 3.1 μmol/m2
matrix
silica gel, spherical particle platform
matrix active group
C18 (octadecyl) phase
particle size
3 μm
pore size
120 Å
application(s)
food and beverages
separation technique
reversed phase
General description
SUPELCOSIL LC-DB phases are specially deactivated for basic compounds. These columns provide shorter retention, better peak shape, and higher efficiency for organic bases than can be obtained on other Type A silica reversed-phase columns.
Application
SUPELCOSIL™ LC-18-DB HPLC column may be used in the determination of 8-oxoguanine in samples of deoxyribonucleic acid (DNA) using gas chromatography coupled with mass spectrometry (GC-MS)and reversed-phase high performance liquid chromatography coupled with electrochemical detection (HPLC-EC)
Legal Information
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
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Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Determination of 8-oxoguanine in DNA by gas chromatography-mass spectrometry and HPLC-electrochemical detection: overestimation of the background level of the oxidized base by the gas chromatography-mass spectrometry assay.
Ravanat L-J, et al.
Chemical Research in Toxicology, 8(8), 1039-1045 (1995)
E Terjéki et al.
Journal of pharmaceutical and biomedical analysis, 24(5-6), 913-920 (2001-03-15)
RGH-1756 (1-(2-methoxy-phenyl)-4-(4-[4-(6-imidazo[2,1-b]-thiazolyl)-phenoxy]-butyl)-piperazine dimethansulphonate) is a novel atypical antipsychotic candidate of Gedeon Richter Ltd. A new HPLC method has been developed and validated for the quantitative determination of RGH-1756 in dog and rat plasma. The compound and the internal standard are
J S Patrick et al.
Analytical biochemistry, 199(1), 125-131 (1991-11-15)
A rapid, isocratic method for the determination of tryptophan in Escherichia coli fermentation broths by reversed-phase HPLC is described. Tryptophan can be measured in fermentations containing either chemically defined media or media with hydrolyzed protein supplements. The procedure was rugged
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 58978 | 04061838549983 |