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About This Item
Empirical Formula (Hill Notation):
C15H22O
CAS Number:
Molecular Weight:
218.33
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
grade
primary reference standard
product line
phyproof® Reference Substance
assay
≥90.0% (GC)
manufacturer/tradename
PhytoLab
application(s)
food and beverages
format
neat
storage temp.
2-8°C
SMILES string
C\C1=C/CC(C)(C)\C=C\C(=O)\C(C)=C\CC1
InChI
1S/C15H22O/c1-12-6-5-7-13(2)14(16)9-11-15(3,4)10-8-12/h7-9,11H,5-6,10H2,1-4H3/b11-9+,12-8+,13-7+
InChI key
GIHNTRQPEMKFKO-SKTNYSRSSA-N
General description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol Actions
TRAIL-induced apoptosis potentiator; DR4 and DR5 inducer
Zerumbone is a TRAIL-induced apoptosis potentiator. It potentiates TRAIL-induced apoptosis through the up-regulation of DR4 and DR5 expression and the down-regulation of cFLIP. Zerumbone has very little or no cytotoxic effect on the normal human endothelial cells and dermal fibroblasts. Zerumbone is a sesquiterpene isolated from in Zingiber zerumbet Smith (wild ginger).
Other Notes
This compound is commonly found in plants of the genus: curcuma zingiber
Legal Information
phyproof is a registered trademark of PhytoLab GmbH & Co. KG
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Acute 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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