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Showing 1-30 of 125 results for "05160" within Papers
Hans F N Kvitvang et al.
Analytical chemistry, 83(7), 2705-2711 (2011-03-11)
Metabolite profiling methods are important tools for measurement of metabolite pools in biological systems. While most metabolite profiling methods report relative intensities or depend on a few internal standards representing all metabolites, the ultimate requirement for a quantitative description of
H T Benzon et al.
British journal of anaesthesia, 111 Suppl 1, i96-113 (2013-12-18)
The new oral anticoagulants are approved for a variety of clinical syndromes, including the prevention of stroke in atrial fibrillation, acute coronary syndromes, treatment of venous thromboembolism (VTE), and prevention of venous thrombosis after total joint surgery or hip fracture.
Robert G Hart et al.
The Canadian journal of cardiology, 29(7 Suppl), S71-S78 (2013-06-29)
Chronic kidney disease (CKD) is prevalent in elderly patients with atrial fibrillation and is an independent risk factor for stroke. Warfarin anticoagulation is efficacious for stroke prevention in atrial fibrillation patients with moderate CKD (stage III, estimated glomerular filtration rate
I M Karmanskiĭ
Voprosy meditsinskoi khimii, 23(4), 530-534 (1977-07-01)
Native lipoproteins of low density from human blood serum were intensively hydrolyzed by pepsin in 0.1 M solution of beta-alanine-HCl at pH 1.9. About 50% and 90% of all the protein part of the substances were split off within 60
Su Emmanuelle Degirmenci et al.
La Revue du praticien, 63(7), 976-979 (2013-10-31)
The new direct oral anticoagulants currently available are dabigatran, rivaroxaban and apixaban. These three drugs have been labeled in France for the prevention of venous thromboembolism after elective orthopaedic surgery including total hip or knee arthroplastly. Rivaroxaban is also labeled
ACP Journal Club. Review: Dabigatran does not differ from vitamin K antagonists for mortality or major bleeding.
Alex Gallus
Annals of internal medicine, 160(8), JC5-JC5 (2014-04-16)
Julie Y Culbertson et al.
Nutrients, 2(1), 75-98 (2010-01-01)
Muscle carnosine has been reported to serve as a physiological buffer, possess antioxidant properties, influence enzyme regulation, and affect sarcoplasmic reticulum calcium regulation. Beta-alanine (β-ALA) is a non-essential amino acid. β-ALA supplementation (e.g., 2-6 grams/day) has been shown to increase
K E Tiedje et al.
Neurochemistry international, 57(3), 177-188 (2010-06-15)
This review discusses the role of beta-alanine as a neurotransmitter. Beta-alanine is structurally intermediate between alpha-amino acid (glycine, glutamate) and gamma-amino acid (GABA) neurotransmitters. In general, beta-alanine satisfies a number of the prerequisite classical criteria for being a neurotransmitter: beta-alanine
[Venous thromboembolism. Currently it is worthwhile to use anticoagulants longer].
Dirk Einecke
MMW Fortschritte der Medizin, 155(6), 26-27 (2013-05-25)
Extended anticoagulation in venous thromboembolism.
Sam Schulman
The New England journal of medicine, 368(24), 2329-2329 (2013-06-14)
Benjamin A Steinberg et al.
BMJ (Clinical research ed.), 348, g2116-g2116 (2014-04-16)
Atrial fibrillation increases the risk of stroke, which is a leading cause of death and disability worldwide. The use of oral anticoagulation in patients with atrial fibrillation at moderate or high risk of stroke, estimated by established criteria, improves outcomes.
Doug Coyle et al.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 16(4), 498-506 (2013-06-26)
The primary objective was to assess the cost-effectiveness of new oral anticoagulants compared with warfarin in patients with nonvalvular atrial fibrillation. Secondary objectives related to assessing the cost-effectiveness of new oral anticoagulants stratified by center-specific time in therapeutic range, age
Response to letters regarding article, “Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Randomized Trial”.
Jeff S Healey et al.
Circulation, 127(11), e506-e506 (2013-05-07)
Jiro Arima et al.
Journal of biotechnology, 147(1), 52-58 (2010-03-23)
Synthesis of beta-alanine (beta-Ala) containing dipeptide using S9 aminopeptidase from Streptomyces thermocyaneoviolaceus NBRC14271 (S9AP-St) was demonstrated with beta-Ala-benzyl ester (-OBzl) and various L-aminoacyl derivatives. For synthesis of beta-Ala-containing dipeptide, beta-Ala-OBzl was used preferentially as the acyl donor for S9AP-St, producing
Jan Heyland et al.
Microbial biotechnology, 3(1), 74-83 (2011-01-25)
β-Peptides and their derivates are usually stable to proteolysis and have an increased half-life compared with α-peptides. Recently, β-aminopeptidases were described as a new enzyme class that enabled the enzymatic degradation and formation of β-peptides. As an alternative to the
Partha Sardar et al.
The American journal of cardiology, 113(7), 1173-1177 (2014-02-12)
Dabigatran is a novel oral anticoagulant and may be useful during atrial fibrillation (AF) ablation for prevention of thromboembolic events. However, the benefits and adverse effects of periprocedural dabigatran therapy have not been thoroughly evaluated. A meta-analysis was performed to
Activated prothrombin complex concentrate for the prevention of dabigatran-associated bleeding.
Henna Wong et al.
British journal of haematology, 166(1), 152-153 (2014-03-13)
Roger C Harris et al.
Nestle Nutrition Institute workshop series, 76, 61-71 (2013-08-01)
Carnosine is a dipeptide of β-alanine and L-histidine found in high concentrations in skeletal muscle. Combined with β-alanine, the pKa of the histidine imidazole ring is raised to ∼6.8, placing it within the muscle intracellular pH high-intensity exercise transit range.
Roger C Harris et al.
Medicine and sport science, 59, 1-17 (2012-10-19)
Glycolysis involves the oxidation of two neutral hydroxyl groups on each glycosyl (or glucosyl) unit metabolised, yielding two carboxylic acid groups. During low-intensity exercise these, along with the remainder of the carbon skeleton, are further oxidised to CO(2) and water.
Dorothea Baumann et al.
Deutsche medizinische Wochenschrift (1946), 139(30), 1539-1539 (2014-07-30)
A 90-year-old female patient treated with dabigatran for atrial fibrillation presented emergently with a spontaneous vaginal bleeding due to endometrium carcinoma. Laboratory analysis revealed azotemia consistent with acute-on-chronic renal failure. Coagulation was deranged (prolongation of activated partial thromboplastin time (aPTT)
Dabigatran, ROCKET atrial fibrillation, and beyond: basic science, mechanisms of agents, monitoring, and reversal.
Kenneth A Bauer
Stroke, 44(6 Suppl 1), S38-S40 (2013-06-05)
Prescrire international, 22(139), 155-159 (2013-07-20)
Dabigatran, rivaroxaban and apixaban are oral anticoagulants used to prevent or treat thrombosis in a variety of situations. Like all anticoagulants, these drugs can provoke bleeding. How should patients be managed if bleeding occurs during dabigatran, rivaroxaban or apixaban therapy?
B V Bloch et al.
The bone & joint journal, 96-B(1), 122-126 (2014-01-08)
Since the introduction of the National Institute for Health and Care Excellence (NICE) guidelines on thromboprophylaxis and the use of extended thromboprophylaxis with new oral agents, there have been reports of complications arising as a result of their use. We
The importance of postapproval data for dabigatran.
Rita F Redberg
JAMA internal medicine, 175(1), 25-25 (2014-11-05)
Plasma dabigatran activity one week after discontinuation despite normal renal function.
Jecko Thachil et al.
The American journal of medicine, 126(8), e5-e6 (2013-06-27)
Sandra Milasta et al.
Molecular pharmacology, 69(2), 479-491 (2005-11-12)
When expressed via an inducible promoter in human embryonic kidney 293 cells, the rat Mas-related gene D (rMrgD) receptor responded to beta-alanine but not L-alanine by elevating intracellular [Ca(2+)], stimulating phosphorylation of the mitogenactivated protein kinases known as extracellular signal-regulated
André B P Van Kuilenburg et al.
The Biochemical journal, 379(Pt 1), 119-124 (2004-01-07)
DPD (dihydropyrimidine dehydrogenase) constitutes the first step of the pyrimidine degradation pathway, in which the pyrimidine bases uracil and thymine are catabolized to beta-alanine and the R-enantiomer of beta-AIB (beta-aminoisobutyric acid) respectively. The S-enantiomer of beta-AIB is predominantly derived from
Digitalis use in contemporary clinical practice: refitting the foxglove.
Zachary D Goldberger et al.
JAMA internal medicine, 174(1), 151-154 (2013-11-13)
Dabigatran in patients with mechanical heart valves.
Alexander Speirs et al.
The New England journal of medicine, 370(4), 382-382 (2014-01-24)
Ajay Yadlapati et al.
The American journal of cardiology, 113(8), 1362-1363 (2014-03-01)
Direct-current cardioversion (DCCV) for persistent atrial fibrillation or atrial flutter (AF) carries a risk of thromboembolic events (TEs). Therapeutic anticoagulation with warfarin is recommended for 3 to 4 weeks before and 4 weeks after DCCV to reduce TE; however, the
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