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The Effective Use of Protein Kinase Inhibitors
87 55 92 90 83 75 82 103 85 95 98
90 88 129 112 96 93 95 91 106 98 65 104 73 102 96 95 78 98 105 60 75 86
69 15 20 86 82
The Effective Use of Protein Kinase Inhibitors
78 98 105 60 75 86
69 15 20 86 82 69 114 115 27 46 105 109 99 44
54 92 4 5 5 29 23 5
113 124 104 105 80 83 62 90 85
Data Sheet - 27048
Soc. Exp. Biol. Med., 47, 108 (1941)
2. W.B. Christensen,J. Bacteriol. 69, 103 (1946)
3. E. Thal, T.H. Chen,J. Bacteriol. 69, 103 (1955)
4. J. MacFaddin, Biochemical Tests for Identification of Medical
Aldrich Polymer Products Application - Initiators
°C (Solvent)
44,146-5 tert-Amyl peroxybenzoate 99 (benzene)
11,816-8 4,4-Azobis(4-cyanovaleric acid) Acetone 70 4.6 x 10-5 69 (water)
Water 69 1.9 x 10-5
Water 80 9.0 x 10-5
38,021-0 1,1'-Azobis
Anti-MMP-9, near C-terminus, clone 56-2A4 - Data Sheet
activation of
matrix metalloproteinase 2 (gelatinase A) in human gastric carcinomas. Int. J. Cancer 69:9-
USA & Canada
Quality Control Range Sheet- A6041-103 and A6041-203
Control 1 27 - 57 pg/mL IL-5 Control 1 68 - 142 pg/mL
Control 2 136 - 283 pg/mL Control 2 358 - 743 pg/mL
Quality Control Range Sheet- PCC-121 and PCC-221
Control 1 59 - 123 pg/mL IL-4 Control 1 103 - 213 pg/mL
Control 2 422 - 876 pg/mL Control 2 805 - 1671 pg/mL
TGFα
Quality Control Ranges: MILLIPLEX® MAP Non-Human Primate Cytokine/Chemokine Kit
Control 1 59 - 123 pg/mL IL-4 Control 1 103 - 213 pg/mL
Control 2 422 - 876 pg/mL Control 2 805 - 1671 pg/mL
TGFα
Anti-NeuN, clone A60 - Data Sheet
PNAS (2006) 103:7112-7117.
83) Koizumi, H., et al., Nature Neuroscience (2006) 9:779-786.
84) Goetz, A., et al., PNAS (2006) 103:11063-11068.
85) Steele, A., et al., PNAS (2006) 103:3416-3421.
GR 144053- Non-peptide antagonist of the platelet glycoprotein IIb/IIIa (GP IIb/IIIa) fibrinogen receptor
. Biochem., 182, 101-108 (1998).
68. Kenner, K.A., et al., J. Biol. Chem., 271, 19810-19819 (1996).
69. Marion, E., et al., Diabetes, 51, 2012-2017 (2002).
70. Elchebly, M., et al., Science, 283, 1423-1426
Technical Bulletin - MWGF200
interaction
of FAT10 and VCP (p97)”). Heinrich-Heine-
Universität Konstanz, Dr. rer. nat. dissertation,
p. 69 (2015).
10. Olivares, Philip, “Homeostasis of Primary and
Secondary Metabolites”. University of
Product Information Sheet - P5568
the
enzyme belongs to the subtilisin family with an active-
site catalytic triad (Asp
39
-His
69
-Ser
224
). The
predominant site of cleavage is the peptide bond
adjacent to the carboxyl
Product Information Sheet - P8044
the
enzyme belongs to the subtilisin family with an active-
site catalytic triad (Asp
39
-His
69
-Ser
224
). The
predominant site of cleavage is the peptide bond
adjacent to the carboxyl
Product Information Sheet - ECORIRO
pUC18
5 5 1 0 2 1 1 1
sigma-aldrich.com
http://sigma-aldrich.com
www.lifescience.roche.com/certificates
References
1 Hedgpeth, J. et al. (1972) Proc. Natl. Acad. Sci USA 69, 3448.
Data Sheet - X1504
(1997).
5. Wood, R.D., Biochimie, 81, 39-44 (1999).
6. You, J.-S., et al., J. Biol. Chem., 278, 747-7485
(2003).
7. Sancar, A., and Reardon, J.T., Adv. Protein Chem.,
69, 43-71 (2004).
8
Examination of Non-Specifically Bound Proteins and Peptides Following Depletion of Twenty High Abundance Proteins from Human Plasma
precursor 46 1 69 2
IPI00021842 Apolipoprotein E precursor 509 8
IPI00299435 Apolipoprotein F precursor 124 1
IPI00030739 Apolipoprotein M 70 1
IPI00186903 Apolipoprotein-L1 precursor 103 1
IPI00297181
Data Sheet - X1004
23468
(1997).
5. Wood, R.D., Biochimie, 81, 39-44 (1999).
6. You, J.-S., et al, J. Biol. Chem., 278, 747-7485
(2003).
7. Sancar, A., and Reardon, J.T., Adv. Protein Chem.,
69, 43-71 (2004).
Data Sheet - X1129
23468
(1997).
5. Wood, R.D., Biochimie, 81, 39-44 (1999).
6. You, J.-S., et al, J. Biol. Chem., 278, 747-7485
(2003).
7. Sancar, A., and Reardon, J.T., Adv. Protein Chem.,
69, 43-71 (2004).
Data Sheet - P2308
the
enzyme belongs to the subtilisin family with an
active-site catalytic triad (Asp
39
, His
69
, and Ser
224
). The
predominant site of cleavage is the peptide bond
adjacent to the carboxyl
Data Sheet - X0879
(1997).
5. Mu, D. et al., J. Biol. Chem., 270, 2425-2418
(1995).
6. Liu, Y., et al., Biochemistry, 44, 7361-7368 (2005).
7. Sancar, A., and Reardon, J.T., Adv. Protein Chem.,
69, 43-71 (2004
Data Sheet - X1629
(1997).
5. Wood, R.D., Biochimie, 81, 39-44 (1999).
6. You, J.-S., et al., J. Biol. Chem., 278, 7476-7485
(2003).
7. Sancar, A., and Reardon, J.T., Adv. Protein
Chem., 69, 43-71 (2004).
Data Sheet - G2279
Biol., 103, 2229
(1986).
2. Duden, R., et al., Cell, 64, 649 (1991).
3. Donaldson, J. G., et al., J. Cell Biol., 111, 2295
(1990).
4. Donaldson, J. G., et al., Cell Biol., 112, 589 (1991).
5. Orci
Data Sheet - X1254
23468
(1997).
5. Wood, R.D., Biochimie, 81, 39-44 (1999).
6. You, J.-S., et al, J. Biol. Chem., 278, 7476-7485
(2003).
7. Sancar, A., and Reardon, J.T., Adv. Protein Chem.,
69, 43-71 (2004).
8
Product Information Sheet - S7388
proteinase from
Aspergillus fumigatus culture filtrate. FEBS Letters,
308, 65-69, (1992).
5. Nakajima, K., et al., Mapping the extended
substrate binding site of cathepsin G and human
Data Sheet - C9464
of cholesteryl
oleate liquid crystals by hormone-sensitive lipase.
J. Biochem. (Tokyo), 113, 264-69 (1995).
17. Pietsch, M., and Gutschow, M., Alternate substrate
inhibition of cholesterol esterase
Product Information Sheet - SE120057
140-5 (1990).
5. Rose, M.P., Follicle stimulating hormone
international standards and reference preparations
for the calibration of immunoassays and
bioassays. Clin. Chim. Acta, 273(2), 103-17
Protein Tyrosine Phosphatases- Potential Roles in Disease
insulin signaling pathway, including PTPα and PTPε
[64], PTP-LAR [65,66], PTP1B [67,68] and SHIP-2 [69].
Recently, a PTP1B knockout has been developed that has
provided evidence that PTP1B is a key regulator
Data Sheet - P6556
Angerer, L.M., et al., Methods Enzymol., 152, 649-
661 (1987).
16. Sakaguchi, S., et al., J. Virology, 69(12), 7586-7592
(1995).
17. Bennion, B.J., and Daggett, V., Clin. Chem.,
48(12), 2105-2114 (
XP725 Antibody Number-Lot Number 071M4826
66 67 68 89 90 91 92
1.6 21 22 23 24 45 46 47 48 69 70 71 72 93 94 95 96
2.1 97 98 99 100 121 122 123 124 145 146 147 148 169 170 171 172
2.2 101
Product Information Sheet - SE120032
pheochromocytoma (89%), carcinoid tumors (80%),
nonfunctioning tumors of the endocrine pancreas
(69%), and medullary carcinoma of the thyroid (50%).
Only 7% of control subjects have elevated CgA and
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