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Showing 1-30 of 115 results for "105-60-2" within Papers
Barbara Chen et al.
Bioorganic & medicinal chemistry letters, 23(21), 5949-5952 (2013-09-17)
We have synthesized a novel vitamin D receptor agonist VS-105 ((1R,3R)-5-((E)-2-((3αS,7αS)-1-((R)-1-((S)-3-hydroxy-2,3-dimethylbutoxy)ethyl)-7α-methyldihydro-1H-inden-4(2H,5H,6H,7H,7αH)-ylidene)ethylidene)-2-methylenecyclohexane-1,3-diol). Preparation of a-ring phenylphosphine oxide 11, followed by Wittig-Horner coupling of 11 with the protected 25-hydroxy Grundmann's ketone 22 generated the precursor 12. Deprotection of the TBDMS groups of
Abbas Khani-Hanjani et al.
The Journal of rheumatology, 29(7), 1358-1365 (2002-07-26)
To examine the relationship between disease severity in patients with confirmed rheumatoid arthritis (RA) and the carriage of alleles expressing the high risk epitope (HRE) QK/QR/RRRAA or the low risk epitope (LRE) DERAA at positions 70-74 of the third hypervariable
Lynn A Gregory et al.
The Journal of biological chemistry, 279(28), 29391-29397 (2004-05-01)
MAp19 is an alternative splicing product of the MASP-2 gene comprising the N-terminal CUB1-epidermal growth factor (EGF) segment of MASP-2, plus four additional residues at its C-terminal end. Like full-length MASP-2, it forms Ca(2+)-dependent complexes with mannan-binding lectin (MBL) and
R P Colliton et al.
Human mutation, 17(2), 151-152 (2001-02-17)
Alagille syndrome (AGS) is an autosomal dominant disorder caused by mutations in Jagged1 (JAG1), a ligand in the evolutionarily conserved Notch signaling pathway. Previous studies have demonstrated that a wide spectrum of JAG1 mutations result in AGS. These include total
C Z Alvarado et al.
Poultry science, 83(6), 1039-1046 (2004-06-23)
Pale, soft, and exudative (PSE) meat is a growing problem in the turkey industry and has been associated with processing conditions such as slow carcass chilling. The development of PSE meat is caused by protein denaturation resulting from a rapid
Alexander S Day et al.
Biosensors & bioelectronics, 179, 113099-113099 (2021-03-01)
The SARS-CoV-2 pandemic, an ongoing global health crisis, has revealed the need for new technologies that integrate the sensitivity and specificity of RT-PCR tests with a faster time-to-detection. Here, an emulsion loop-mediated isothermal amplification (eLAMP) platform was developed to allow
Asli Ertekin et al.
The Journal of biological chemistry, 287(20), 16541-16549 (2012-03-20)
CDK2AP1 (cyclin-dependent kinase 2-associated protein 1), corresponding to the gene doc-1 (deleted in oral cancer 1), is a tumor suppressor protein. The doc-1 gene is absent or down-regulated in hamster oral cancer cells and in many other cancer cell types.
Jana Reiterová et al.
Kidney & blood pressure research, 25(2), 87-90 (2002-06-22)
The phenotypic variability of autosomal dominant polycystic kidney disease (ADPKD) cannot be explained only by various mutations of two known genes (PKD1 and PKD2), but the influence of other unknown factors should also be considered. Impairment of endothelial function has
Andrew C Kithas et al.
Nitric oxide : biology and chemistry, 104-105, 51-60 (2020-09-27)
Nitric oxide synthase (NOS) inhibition with N(G)-monomethyl-l-arginine (L-NMMA) is often used to assess the role of NO in human cardiovascular function. However, the window of effect for L-NMMA on human vascular function is unknown, which is critical for designing and
Yan Yin et al.
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 46(3), 269-272 (2012-07-18)
To investigate the distribution of estrogen receptor beta (ERbeta) gene polymorphisms between the Uygurs and the Hans in Urumqi and the association of the polymorphisms with intrahepatic cholestasis of pregnancy (ICP). ICP cases and controls from a hospital were recruited
R Stein et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 5(10 Suppl), 3199s-3206s (1999-10-29)
We have shown previously significant antitumor effects using 90Y-MN-14 anti-CEA monoclonal antibody (MAb) for radioimmunotherapy (RAIT) of human medullary thyroid cancer (MTC) xenografts using the TT cell line. The purpose of this investigation was to determine the effect of combining
Beena Kumari et al.
Environmental monitoring and assessment, 182(1-4), 129-132 (2011-01-21)
A supervised field trial was conducted at the CCS Haryana Agricultural University, Hisar to assess the residues of dicofol on cotton, during Kharif season, 2008. Dicofol (Kelthane 18.5EC) was applied at 500 g a.i./ha (T(1)) and 1,000 g a.i./ha T(2))
Marco Antonio Naslausky Mibielli et al.
Journal of pain research, 13, 2531-2541 (2020-10-30)
We report the results of low back pain treatment using a combination of nucleotides, uridine (UTP), cytidine (CMP) and vitamin B12, vs a combination of vitamins B1, B6, and B12. Randomized, double-blind, controlled trial, of a 60-day oral treatment: Group
Edmondo Falleti et al.
Human immunology, 71(10), 999-1004 (2010-07-27)
Genetic polymorphisms of interleukin-6 (IL-6) (-1363G>T, -597G>A, -572G>C, -174G>C, +2954G>C) may affect the outcomes of several diseases. This study was aimed to verify the role of these polymorphisms on the disease progression of patients with hepatitis C virus (HCV) infection
Yung-Chih Chen et al.
American journal of physiology. Endocrinology and metabolism, 313(1), E84-E93 (2017-03-16)
Feeding profoundly affects metabolic responses to exercise in various tissues, but the effect of feeding status on human adipose tissue responses to exercise has never been studied. Ten healthy overweight men aged 26 ± 5 yr (mean ± SD) with a waist circumference of
Hsi-Chin Wu et al.
Journal of clinical laboratory analysis, 20(6), 245-249 (2006-11-23)
Cytokines are reported to be associated with the formation of prostate cancer. Our aim was to investigate whether C/T polymorphisms of the interleukin-2 (IL-2) gene and IL-2 receptor beta (IL-2RB) gene are associated with prostate cancer. We compared the frequency
Agnese D'Agostino et al.
Talanta, 216, 120936-120936 (2020-05-28)
Seed-growth synthesis is a common strategy to prepare silver nanoplates, whose peculiar plasmonic features can be exploited for surface enhanced Raman scattering (SERS) applications. Here we describe the fabrication and characterization of SERS chips using a peculiar in situ seed
Stephen Z Levine et al.
Schizophrenia research, 145(1-3), 125-127 (2013-02-12)
The treatment and measurement of negative symptoms are currently at issue in schizophrenia, but the clinical meaning of symptom severity and change is unclear. To offer a clinically meaningful interpretation of severity and change scores on the Scale for the
Ya Yue et al.
Stem cell research & therapy, 13(1), 186-186 (2022-05-08)
This experimental study was designed as a preclinical study for testing the hypothesis that intrarenal arterial (IRA) transfusion of human umbilical cord-derived mesenchymal stem cells (HUCDMSCs) therapy preserved the residual renal function of diabetic kidney disease (DKD) in rat [induction
S Karthikeyan et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 36(2), 270-277 (2019-01-17)
An efficient analytical method was developed and validated using a modified QuEChERS method and LC-MS/MS for the detection and quantification of neonicotinoid insecticide residues in rice whole grain and rice straw. The samples were extracted using acetonitrile and cleaned up
Yong Li et al.
Zhonghua fu chan ke za zhi, 46(8), 600-604 (2011-12-16)
To evaluate the NLRP7 gene mutations and variants and their expression of genetic approach in hydatidiform mole patients with family history. Six cases of mole patients with family members of mole history and 60 healthy women, taking blood, extracting DNA
Han-wen Sun et al.
Drug testing and analysis, 1(3), 128-134 (2010-04-01)
A novel trivalence dysprosium(Dy(3+))-sensitized chemiluminescence method was developed for the first time for the determination of enoxacin (ENX) using flow-injection sampling based on the chemiluminescence (CL) associated with the reaction of the Dy(3+)-cerium(Ce(IV))-S(2)O(3) (2-)-ENX system and the Dy(3+)-MnO(4) (-) S(2)O(3)
Linda J Romero et al.
Ethnicity & disease, 12(2), 235-241 (2002-05-22)
To determine if the apolipoprotein E E4 (APO E4) allele is associated with cognitive performance in New Mexico Hispanic elderly. We performed a cross-sectional survey of 105 community volunteers, aged 60 years and older, born in New Mexico, with both
Olusegun A Mojiminiyi et al.
Journal of diabetes and its complications, 17(3), 160-168 (2003-05-10)
Despite recent studies showing that serum cystatin C (CC) is a better marker for GFR than the ubiquitously used serum creatinine, its clinical utility remains under evaluation. To evaluate their usefulness in patients with type 2 diabetes mellitus (DM), serum
Patrizia Saccucci et al.
Journal of child neurology, 21(9), 753-756 (2006-09-15)
The etiology of mild mental retardation remains undefined in about 60% of cases. Even though the causes of mild mental retardation are likely to be heterogeneous, the evidence for genetic involvement is increasing, along with the development of specific diagnostic
Shin-Ae Kang et al.
The Journal of biological chemistry, 285(34), 26013-26021 (2010-06-18)
PTK6 (also known as Brk) is a non-receptor-tyrosine kinase containing SH3, SH2, and catalytic domains, that is expressed in more than 60% of breast carcinomas but not in normal mammary tissues. To analyze PTK6-interacting proteins, we have expressed Flag-tagged PTK6
Shin-Ae Kang et al.
The Journal of biological chemistry, 285(34), 26013-26021 (2010-06-18)
PTK6 (also known as Brk) is a non-receptor-tyrosine kinase containing SH3, SH2, and catalytic domains, that is expressed in more than 60% of breast carcinomas but not in normal mammary tissues. To analyze PTK6-interacting proteins, we have expressed Flag-tagged PTK6
J G Förster et al.
Acta anaesthesiologica Scandinavica, 57(7), 911-919 (2013-03-26)
Articaine and chloroprocaine have recently gained interest as short-acting spinal anaesthetics. Based on previous work comparing articaine 60 mg with chloroprocaine 40 mg, we hypothesised that articaine 40 mg and chloroprocaine 40 mg would produce similar spinal anaesthesa regarding block onset, maximal spread, and
Chun-Ping Chu et al.
PloS one, 8(1), e53863-e53863 (2013-01-26)
The effects of stresscopin (SCP) on rat paraventricular nucleus (PVN) neurons were examined using whole-cell patch-clamp recordings and single-cell reverse-transcription multiplex polymerase chain reaction (SC-RT-mPCR) techniques. Under current-clamp conditions, bath application of SCP (100 nM) induced inhibition in 35.2% (37/105)
Xuan Yang et al.
International journal of nanomedicine, 15, 7155-7171 (2020-10-17)
Tissue engineering approaches seem to be an attractive therapy for tendon rupture. Novel injectable porous gelatin microcryogels (GMs) can promote cell attachment and proliferation, thus facilitating the repair potential for target tissue regeneration. The research objectives of this study were
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