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Showing 1-30 of 42 results for "108-50-9" within Papers
Yunjian Pan et al.
Journal of thoracic disease, 9(8), 2579-2586 (2017-09-22)
To determine the proportion and clinical features of programmed death ligand 1 (PD-L1) expression in East Asian non-small cell lung cancer (NSCLC). PD-L1 expression was assessed by immunohistochemistry (IHC) and tumor proportion score (TPS) with the use of PD-L1 IHC
Yi Jin et al.
Asian Pacific journal of cancer prevention : APJCP, 12(6), 1473-1476 (2011-12-01)
This study was designed to detect the protein expression of VEGF, EGFR and MMP-9, to investigate the potential roles they might play in the pathogenesis of NSCLC and to discuss their relationship and their clinical significance. For 136 cases who
Kyu-Beck Lee et al.
Yonsei medical journal, 44(4), 641-647 (2003-09-02)
Autosomal dominant polycystic kidney disease (ADPKD), a common genetic disease, is characterized by the development of hypertension and end stage renal disease. An increase in the activity of the renin-angiotensin system, due to a renal ischemia caused by cyst expansion
Michele Tonelli et al.
Antiviral research, 91(2), 133-141 (2011-05-31)
Twenty-six 9-aminoacridine derivatives were evaluated in cell-based assays for cytotoxicity and antiviral activity against a panel of 10 RNA and DNA viruses. While seven compounds (9, 10, 14, 19, 21, 22, 24) did not affect any virus and two (6
J Wozney et al.
Nature, 294(5837), 129-135 (1981-11-12)
Fifty-four kilobase pairs (kbp) of cloned chicken DNA containing the entire 38-kbp pro alpha 2 (I) collagen gene have been isolated and characterized. DNA sequence analysis of a select 4 kbp of the gene has precisely described 14 exons which
K Bettayeb et al.
Oncogene, 27(44), 5797-5807 (2008-06-25)
Among the ten pharmacological inhibitors of cyclin-dependent kinases (CDKs) currently in clinical trials, the purine roscovitine (CYC202, Seliciclib) is undergoing phase 2 trials against non-small-cell lung and nasopharyngeal cancers. An extensive medicinal chemistry study, designed to generate more potent analogues
Md Shofikul Islam et al.
Environmental health : a global access science source, 14, 92-92 (2015-12-08)
Cardiovascular diseases (CVDs) and cancers are the major causes of chronic arsenic exposure-related morbidity and mortality. Matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) are deeply involved in the pathogenesis of CVDs and cancers. This study has been designed to evaluate the
Hong Guo et al.
Cancer biotherapy & radiopharmaceuticals, 34(1), 1-6 (2019-01-25)
To investigate the expression levels of matrix metalloproteinases-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in pituitary adenomas (PAs), and to analyze the relationship of the expressions of the two with the prognosis of patients. A total of 108 patients
Jesús Santana-Gálvez et al.
International journal of molecular sciences, 21(9) (2020-05-02)
Nutraceutical combinations that act synergistically could be a powerful solution against colon cancer, which is the second deadliest malignancy worldwide. In this study, curcumin (C), sulforaphane (S), and dihydrocaffeic acid (D, a chlorogenic acid metabolite) were evaluated, individually and in
Shuju Wang et al.
Se pu = Chinese journal of chromatography, 25(2), 226-229 (2007-06-22)
A method for the simultaneous determination of captan and folpet pesticide residues in apples was developed by solid-phase extraction and high performance liquid chromatography. The sample was extracted with acetonitrile and cleaned-up by a mixture of homemade sorbent and silica
S Matsumura et al.
Journal of chromatography. B, Biomedical applications, 681(2), 375-380 (1996-06-07)
A simple and rapid method for the determination of serum amino acids by gas chromatography (GC) has been developed. Following deproteinization of serum with perchloric acid, free amino acids in the supernatant were converted into their N(O,S)-isobutoxycarbonyl methyl ester derivatives
Jian-Yong Zhu et al.
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 30(12), 912-917 (2008-03-14)
To investigate the association between polymorphisms of the serotonin 2A, 2C receptor genes and obstructive sleep apnea-hypopnea syndrome (OSAHS), and therefore to explore the genotypes related to OSAHS. The T102C and A1438G polymorphisms of the serotonin 2A receptor genes and
Brigitte Bauvois et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 22(4), 1115-1122 (2007-01-09)
Dysregulated renal expression of matrix metalloproteinases (MMPs), tissue inhibitors of MMPs (TIMP) and TGF-beta1 contribute to the development of tubulo-interstitial fibrosis characteristic of progressive forms of primary glomerulonephritis (GN). There is little information on the circulating levels of these proteins
Valeria H Springer et al.
Talanta, 83(1), 126-129 (2010-11-03)
A new method to determine metsulfuron methyl (MSM) and chlorsulfuron (CS) in different water samples was developed. It consists in a solid phase extraction (SPE) procedure using multiwalled carbon nanotubes (MWCNTs) as sorbent material in combination with capillary zone electrophoretic
Ruth Holm et al.
International journal of medical sciences, 5(3), 121-126 (2008-06-21)
By using immunohistochemistry we investigated the expression of EphA2 and EphrinA-1 in 217 early squamous cell cervical carcinomas and examine their prognostic relevance. For EphA2 expression, 21 tumors (10%) showed negative, 108 (50%) weak positive, 69 (32%) moderate positive and
Lihua Zhou et al.
Rapid communications in mass spectrometry : RCM, 18(7), 787-794 (2004-03-31)
A mixed matrix of 3-hydroxypicolinic acid (3-HPA) and pyrazinecarboxylic acid (PCA) was used for analysis of a variety of synthetic oligodeoxynucleotides ranging in length from 8-108-mers by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. The experimental results showed that DNA segments
Yiqiang Chen et al.
Journal of AOAC International, 93(1), 335-342 (2010-03-26)
A monoclonal antibody (mAb)-based ELISA and strip test for gentamicin (GEN) and its analogue micronomicin (MIN), are reported in this study. The conjugate gentamicin-glutaraldehyde-bovine serum albumin (GEN-GDA-BSA) was used as an immunogen. The produced anti-GEN mAB exhibited high cross-reactivity with
Y -G Han et al.
Scandinavian journal of immunology, 79(4), 244-250 (2014-05-06)
This study aimed to evaluate the efficacy and safety of an oral DNA vaccine against somatostatin (SS) (pGS/2SS-asd, encoding two copies of somatostatin genes) mediated by attenuated Salmonella choleraesuis C500 without antibiotic resistance gene on piglets growth. A total of
Yihui Luo et al.
Analytical biochemistry, 421(1), 130-137 (2011-12-06)
A single-chain variable fragment (ScFv) complementary DNA (cDNA) library against fenitrothion was constructed, and ScFvs specific for fenitrothion were selected by ribosome display from the library. After three rounds of ribosome display, the ScFv genes were cloned into Escherichia coli
Marcela Videira et al.
Parasitology research, 114(7), 2435-2442 (2015-03-31)
Morphological and molecular procedures were used to describe a new species of microsporidian that infects the muscles of the sub-opercular region and the caudal fins of the freshwater Aequidens plagiozonatus in Brazil. This microsporidian forms whitish xenomas containing variable number
Wendy De Roock et al.
The Lancet. Oncology, 11(8), 753-762 (2010-07-14)
Following the discovery that mutant KRAS is associated with resistance to anti-epidermal growth factor receptor (EGFR) antibodies, the tumours of patients with metastatic colorectal cancer are now profiled for seven KRAS mutations before receiving cetuximab or panitumumab. However, most patients
Glaucia L Veiga et al.
Autonomic neuroscience : basic & clinical, 204, 81-87 (2016-12-10)
It is known that increased sympathetic nerve activity in chronic kidney disease (CKD) progressively worsens kidney function and hypertension. We tested the hypothesis that total renal denervation contributes to reduce sympathetic activation to different beds and improves renal function in
Angela García et al.
Anatomical record (Hoboken, N.J. : 2007), 295(5), 776-785 (2012-02-23)
This study sought to chart the ontogenesis of the goat rumen by histomorphometric examination, scanning electron microscopy and immunohistochemical analysis. A total of 140 goat embryos and fetuses were used, from the first stage of prenatal life until birth. The
T Weimbs et al.
Biochemistry, 31(49), 12289-12296 (1992-12-15)
Proteolipid protein (PLP), the major integral membrane protein of central nervous system myelin, contains 14 cysteine residues within its 276-residue polypeptide chain. We determined the state of all cysteine residues and localized four of them as free thiols at positions
V Sanna et al.
Haemophilia : the official journal of the World Federation of Hemophilia, 14(4), 796-803 (2008-05-08)
Haemophilia A (HA) is an X-linked recessive haemorrhagic disorder caused by a deficiency of coagulation factor VIII. Disease causative mutations are heterogeneous and spread all over the F8 gene sequence, with the exception of intron 22 inversion occurring in about
John M Starr et al.
Mechanisms of ageing and development, 129(12), 745-751 (2008-11-04)
Telomere shortening is a biomarker of cellular senescence and is associated with a wide range of age-related disease. Oxidative stress is also associated with physiological aging and several age-related diseases. Non-human studies suggest that variants in oxidative stress genes may
D Nicholas Bateman et al.
Lancet (London, England), 383(9918), 697-704 (2013-12-03)
Paracetamol poisoning is common worldwide. It is treated with intravenous acetylcysteine, but the standard regimen is complex and associated with frequent adverse effects related to concentration, which can cause treatment interruption. We aimed to ascertain whether adverse effects could be
G Bernatchez et al.
The Journal of membrane biology, 184(2), 143-159 (2001-11-24)
The structural determinants of mibefradil inhibition were analyzed using wild-type and inactivation-modified Ca(V)1.2 (alpha1C) and Ca(V)2.3 (alpha1E) channels. Mibefradil inhibition of peak Ba2+ currents was dose- and voltage-dependent. An increase of holding potentials from -80 to -100 mV significantly shifted
R Holm et al.
Journal of clinical pathology, 61(1), 59-63 (2007-05-01)
To determine the levels of expression of ZNF652 and its relevance to prognosis in vulvar squamous cell carcinomas. 22 cases of vulvar intraepithelial neoplasia (VIN) and tumours from 217 patients with vulvar squamous cell carcinomas were investigated for expression of
Se Joon Woo et al.
JAMA ophthalmology, 139(1), 68-76 (2020-11-20)
Neovascular age-related macular degeneration is the leading cause of blindness in individuals 50 years or older. The availability of a ranibizumab biosimilar product (SB11) may facilitate access to an effective alternative to this treatment. To demonstrate equivalence of efficacy, similar
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