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Showing 1-10 of 10 results for "122-57-6" within Papers
Kaliandra A Gonçalves et al.
BMC structural biology, 10, 15-15 (2010-06-10)
The adaptor protein RACK1 (receptor of activated kinase 1) was originally identified as an anchoring protein for protein kinase C. RACK1 is a 36 kDa protein, and is composed of seven WD repeats which mediate its protein-protein interactions. RACK1 is
T Vulliamy et al.
Clinical genetics, 81(1), 76-81 (2011-01-05)
Dyskeratosis congenita (DC) is a heterogeneous bone marrow failure syndrome with seven disease-causing genes identified to date, six of which are linked to telomere maintenance. Mutations in one of these genes (TINF2), which encodes a component of the shelterin complex
Mei-ling Zheng et al.
Zhonghua fu chan ke za zhi, 41(3), 152-154 (2006-04-28)
To investigate the relationship between the recurrent spontaneous abortion and soluble human leukocyte antigen (HLA) DQB1 gene polymorphism. Sixty one cases with recurrent spontaneous abortion were included in study group. Of them, 31 were anticardiolipin antibody (ACA) positive, while 30
G P Skliris et al.
British journal of cancer, 95(5), 616-626 (2006-08-02)
To analyse the phenotype of breast tumours that express oestrogen receptor-beta (ERbeta) alone tissue microarrays were used to investigate if ERbeta isoforms are associated with specific prognostic markers and gene expression phenotypes in ERalpha-negative tumours. ERalpha-negative tumours were positive for
M R Chruscielewska-Kiliszek et al.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 15(1), e48-e55 (2012-09-26)
Chronic radiation proctitis is a long-term complication of radiation therapy for pelvic malignancy. The aim of this study was to compare the efficacy and safety of two treatment regimens, sucralfate or placebo, following argon plasma coagulation (APC) for chronic haemorrhagic
Brett M Mitchell et al.
American journal of physiology. Heart and circulatory physiology, 285(5), H2165-H2170 (2003-07-12)
GTP cyclohydrolase 1 is the rate-limiting enzyme in production of tetrahydrobiopterin, a necessary cofactor for endothelial nitric oxide synthase. We tested the hypothesis that inhibition of tetrahydrobiopterin synthesis impairs endothelium-dependent relaxation and increase blood pressure in rats. 2,4-Diamino-6-hydroxypyrimidine (DAHP), a
Xiao-Jing Lin et al.
Shock (Augusta, Ga.), 32(5), 524-529 (2009-03-20)
The present study was attempted to assess the prophylactic and the therapeutic effect of human recombinant activated protein C (APC; drotrecogin-alpha, activated) in experimental heat stroke. Anesthetized rats were divided into two groups and given vehicle solution 1 h before
Ganna Tolstanova et al.
The Journal of pharmacology and experimental therapeutics, 328(3), 749-757 (2008-12-09)
In ulcerative colitis (UC), an increased expression of vascular endothelial growth factor (VEGF) correlates with disease activity, but a causal relationship is unknown. We tested the hypothesis that VEGF plays a mechanistic role in the pathogenesis of experimental UC and
Masaya Tanno et al.
Circulation research, 93(3), 254-261 (2003-06-28)
The ischemic activation of p38alpha mitogen-activated protein kinase (p38alpha-MAPK) is thought to contribute to myocardial injury. Under other circumstances, activation is through dual phosphorylation by MAPK kinase 3 (MKK3). Therefore, the mkk3-/- murine heart should be protected during ischemia. In
Karen M Edmond et al.
Lancet (London, England), 385(9975), 1315-1323 (2014-12-17)
Results of randomised controlled trials of newborn (age 1-3 days) vitamin A supplementation have been inconclusive. The WHO is coordinating three large randomised trials in Ghana, India, and Tanzania (Neovita trials). We present the findings of the Neovita trial in
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