CN
Search Within
133-13-1
Applied Filters:
Keyword:'133-13-1'
Showing 1-30 of 71 results for "133-13-1" within Papers
Wayde M Weston et al.
Life sciences, 71(16), 1849-1862 (2002-08-15)
In mammalian cells, including those of the embryonic palate, the level of phosphorylation of cellular proteins at any given time reflects the activities of protein kinases and protein phosphatases. Both protein phosphatase-1 (PP-1) and PP-2A inhibit cAMP-mediated increases in transcription
R Schreck et al.
The Journal of clinical endocrinology and metabolism, 79(3), 791-798 (1994-09-01)
Iodothyronine 5'-deiodinase isoenzymes generate the thyroid hormone 3,3',5-triiodothyronine from the prohormone L-T4. Basal and retinoic acid (RA)-induced type I 5'-deiodinase (5'DI) activities were studied in human thyroid carcinoma cell lines. In the follicular thyroid carcinoma line FTC-133, nanomolar concentrations of
Joseph T Blois et al.
The Journal of biological chemistry, 279(29), 30123-30132 (2004-05-13)
The cAMP-response element-binding protein (CREB) is activated by phosphorylation on Ser-133 and plays a key role in the proliferative and survival responses of mature B cells to B cell receptor (BCR) signaling. The signal link between the BCR and CREB
Daniela Boehm et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(42), 18103-18108 (2010-10-07)
Epstein Barr virus latent membrane protein 1 (LMP1) induces NF-κB activation through transformation effector sites (TES) 1 and 2, both of which are critical for B-lymphocyte transformation. TES2 principally activates canonical NF-κB, which we confirm is NF-κB essential modifier (NEMO)-dependent
Yan Lu et al.
Journal of cardiovascular pharmacology, 64(5), 420-430 (2014-07-01)
: Endocannabinoids are bioactive amides, esters, and ethers of long-chain polyunsaturated fatty acids. Evidence suggests that activation of the endocannabinoid pathway offers cardioprotection against myocardial ischemia, arrhythmias, and endothelial dysfunction of coronary arteries. As cardiac hypertrophy is a convergence point
S Escaff et al.
British journal of cancer, 102(5), 922-929 (2010-02-18)
Extracellular matrix metalloproteases (MMPs) have raised an extraordinary interest in cancer research because of their potential role in basal membrane and extracellular matrix degradation, consequently facilitating tumour invasion and metastases development. An immunohistochemical study was performed using tissue arrays and
Jessy J Alexander et al.
Biochimica et biophysica acta, 1772(10), 1143-1149 (2007-10-19)
This study has employed high-resolution NMR spectroscopy of kidney extracts to study alterations in the concentrations of amino acids and glucose in systemic lupus erythematosus (SLE). We used the well-established mouse model of SLE, MRL/lpr, and their congenic controls, MRL/+.
Alan N Baer et al.
Arthritis care & research, 68(2), 254-260 (2015-06-04)
Interferon-inducible protein-16 (IFI16) is an intracellular DNA receptor involved in innate immunity. We evaluated the frequency, phenotypic characteristics, and clinical associations of anti-IFI16 antibodies in patients with primary Sjögren's syndrome (SS), and quantitated expression levels of IFI16 in SS and
Mu-Fa Zou et al.
Bioorganic & medicinal chemistry letters, 12(9), 1249-1252 (2002-04-20)
Synthesis of a series of pure S-(+)-2beta-carboalkoxy-3alpha-[bis(4-fluorophenyl)methoxy]tropanes (>99% ee) was achieved by employing a chiral amine-induced asymmetric reaction of tropinone with methyl cyanoformate as the key step. In this series, all of the S-(+)-enantiomers were 2-fold more potent than their
Edward S Kimball et al.
American journal of physiology. Gastrointestinal and liver physiology, 291(2), G364-G371 (2006-04-01)
Oil of mustard (OM) is a potent neuronal activator that is known to elicit visceral hyperalgesia when given intracolonically, but the full extent to which OM is also proinflammatory in the gastrointestinal tract is not known. We have previously shown
Hidehiko Shimokawa et al.
The Journal of thoracic and cardiovascular surgery, 141(4), 895-898 (2010-11-26)
The purpose of this study was to clarify the role and clinical significance of metastasis associated in colon cancer 1 in resected stage I non-small cell lung cancers. Tumor specimens were collected from 146 consecutive patients who underwent a complete
Natalija Novak et al.
The Journal of allergy and clinical immunology, 115(4), 828-833 (2005-04-05)
Human IL-18 is an inflammatory cytokine that plays a role in atopic diseases, such as atopic eczema (AE), by enhancing IL-4 and IL-13 production and stimulating the synthesis of IgE. To evaluate associations of polymorphisms in the IL18 gene on
Paul M Sincock et al.
Traffic (Copenhagen, Denmark), 4(1), 18-25 (2003-01-22)
TIP47 (tail-interacting protein of 47 kDa) binds to the cytoplasmic domains of mannose 6-phosphate receptors and is required for their transport from endosomes to the trans-Golgi network in vitro and in living cells. TIP47 occurs in cytosol as an oligomer;
Wesam F Farrash et al.
Frontiers in endocrinology, 12, 645881-645881 (2021-06-29)
Assuming myokines underlie some of the health benefits of exercise, we hypothesised that 'high responder trainer' (HRT) rats would exhibit distinct myokine profiles to 'low responder trainers' (LRT), reflecting distinct health and adaptive traits. Blood was collected from LRT and
M J Demeure et al.
Surgery, 108(6), 986-992 (1990-12-01)
The actin cytoskeleton is important for cell structure and motility. A disordered actin architecture has been correlated with a high metastatic potential in melanoma, fibrosarcoma, and colon cancer models. Thyrotropin is known to induce growth and differentiation in cultured thyroid
H K Kim et al.
Human immunology, 61(12), 1274-1280 (2001-02-13)
We examined the distribution of polymorphic elements within the tumor necrosis factor (TNF) gene cluster in 133 normals and in 20 Korean families and compared our data with the results of Caucasians. The genotypes that are shown frequently are TNF
Gamil A Guirgis et al.
The journal of physical chemistry. A, 119(47), 11532-11547 (2015-10-06)
The FT-microwave spectrum (6.5-26 GHz) of (chloromethyl)fluorosilane (ClCH2-SiH2F) has been recorded and 250 transitions for the parent species along with (13)C, (37)Cl, (29)Si, and (30)Si isotopologues have been assigned for trans conformer. Infrared spectra (3100 to 400 cm(-1)) of gas
Young Sun Kim et al.
The Journal of biological chemistry, 281(51), 39051-39061 (2006-10-26)
Down syndrome candidate region 1 (DSCR1), an endogenous inhibitor of calcineurin, inhibits the expression of genes involved in the inflammatory response. To elucidate the molecular basis of these anti-inflammatory effects, we analyzed the role of DSCR1 in the regulation of
C A McWherter et al.
Biochemistry, 38(14), 4564-4571 (1999-04-09)
Myelopoietins (MPOs) are a family of engineered dual interleukin-3 (IL-3) and granulocyte colony-stimulating factor (G-CSF) receptor agonists that are superior in comparison to the single agonists in their ability to promote the growth and maturation of hematopoietic cells of the
Vincent Bekker et al.
Human heredity, 67(3), 206-216 (2008-12-17)
The claudin-1 gene (CLDN1) is a member of a family of genes that encodes proteins found in tight junctions and it has recently been implicated as one of several receptors for late stage binding of hepatitis C virus (HCV). Exploration
L Audi et al.
The Journal of clinical endocrinology and metabolism, 95(4), 1876-1888 (2010-02-13)
Androgen receptor (AR) gene mutations are the most frequent cause of 46,XY disorders of sex development (DSD) and are associated with a variety of phenotypes, ranging from phenotypic women [complete androgen insensitivity syndrome (CAIS)] to milder degrees of undervirilization (partial
Lisa A Cassis et al.
American journal of physiology. Heart and circulatory physiology, 296(5), H1660-H1665 (2009-03-03)
Infusion of ANG II in hyperlipidemic mice augments atherosclerosis and causes formation of abdominal aortic aneurysms (AAAs). The purpose of this study was to define the contribution of ANG II-induced hypertension to these vascular pathologies. Male apolipoprotein E (apoE)- and
P Dick et al.
European journal of clinical investigation, 35(12), 731-737 (2005-11-30)
A functional GT dinucleotide length polymorphism in the haem oxygenase-1 (HO-1) gene promoter is thought to be involved in the pathogenesis of cardiovascular disease. Short (< 25) (GT)n repeats are suggested to facilitate enhanced HO-1 up-regulation in response to injury
Eduard Orvisky et al.
Molecular genetics and metabolism, 76(4), 262-270 (2002-09-05)
Gaucher disease, the inherited deficiency of lysosomal glucocerebrosidase, presents with a wide spectrum of clinical manifestations including neuronopathic and non-neuronopathic forms. While the lipid glucosylceramide is stored in both patients with Gaucher disease and in a null allele mouse model
Jane-Ming Lin et al.
Retina (Philadelphia, Pa.), 28(10), 1416-1420 (2008-09-12)
To investigate whether a polymorphism in the complement factor H gene determines the risk for the development of early age-related macular degeneration (AMD). In this retrospective case-control study, we enrolled 133 unrelated Taiwan Chinese patients with early AMD and 180
Hue-Hua L Hong et al.
Toxicologic pathology, 36(5), 720-726 (2008-07-24)
The incidences of alveolar/bronchiolar adenomas and carcinomas in cumene-treated B6C3F1 mice were significantly greater than those of the control animals. We evaluated these lung neoplasms for point mutations in the K-ras and p53 genes that are often mutated in humans.
Wim van der Meer et al.
Journal of endotoxin research, 13(2), 94-100 (2007-07-11)
CD64 is a high-affinity Fc(gamma)RI receptor expressed by activated neutrophils that has been recently evaluated as a potential sepsis parameter. In the present study, the kinetics of neutrophil membrane CD64 expression were examined during a standardized inflammatory response, using a
Xiao-li Zhu et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 41(9), 584-589 (2012-11-20)
To retrospectively analyze KRAS and BRAF gene mutation features in Chinese colorectal cancer (CRC) and their clinicopathologic relationship. 557 colorectal cancer cases were collected, including 325 colon cancer and 232 rectal cancer. PCR amplification and DNA sequencing were used to
Bryan Gannon et al.
The American journal of clinical nutrition, 100(6), 1541-1550 (2014-11-21)
Biofortification is a strategy to relieve vitamin A (VA) deficiency. Biofortified maize contains enhanced provitamin A concentrations and has been bioefficacious in animal and small human studies. The study sought to determine changes in total body reserves (TBRs) of vitamin
Julien Amour et al.
Anesthesiology, 107(3), 452-460 (2007-08-28)
In the diabetic heart, the positive inotropic response to beta-adrenoceptor stimulation is altered and beta1 and beta2 adrenoceptors are down-regulated, whereas beta3 adrenoceptor is up-regulated. In heart failure, beta3-adrenoceptor stimulation induces a negative inotropic effect that results from endothelial nitric
Page 1 of 3