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Showing 31-60 of 71 results for "133-13-1" within Papers
V Pizza et al.
Central nervous system agents in medicinal chemistry, 10(2), 91-96 (2010-06-04)
Genetic factors that increase susceptibility to oxidative stress, endothelial disfunction and, possibly, stroke include angiotensin-converting enzyme gene deletion polymorphism (ACE-DD) and the methylentetrahydropholate reductase (MTHFR) C677-TT polymorphism. The relationship of ACE-DD genotype to ischemic stroke and cardiovascular disease is controversial
Stephen J D O'keefe et al.
American journal of physiology. Gastrointestinal and liver physiology, 290(2), G213-G221 (2005-08-27)
Knowledge of the stimulatory effects of enteral and parenteral (intravenous) feeding on the synthesis and turnover of trypsin would help in the management of acute pancreatitis, because the disease is caused by the premature activation of trypsin. To investigate this
Ole Kristian Berg et al.
The journals of gerontology. Series A, Biological sciences and medical sciences, 75(12), 2269-2277 (2020-04-08)
Maximal strength training (MST) results in robust improvements in skeletal muscle force production, efficiency, and mass. However, the effects of MST on muscle mitochondria are still unknown. Accordingly, the purpose of this study was to examine, from the molecular level
Shigeki Moriguchi et al.
Journal of neurochemistry, 128(6), 927-937 (2013-10-30)
Because the cholinergic system is down-regulated in the brain of Alzheimer's disease patients, cognitive deficits in Alzheimer's disease patients are significantly improved by rivastigmine treatment. To address the mechanism underlying rivastigmine-induced memory improvements, we chronically treated olfactory bulbectomized (OBX) mice
Su-Jin Kim et al.
Molecular and cellular biology, 28(5), 1644-1656 (2007-12-19)
The cyclic AMP (cAMP)/protein kinase A (PKA) cascade plays a central role in beta-cell proliferation and apoptosis. Here, we show that the incretin hormone glucose-dependent insulinotropic polypeptide (GIP) stimulates expression of the antiapoptotic Bcl-2 gene in pancreatic beta cells through
Young-Gun Park et al.
Clinical & experimental ophthalmology, 42(9), 846-855 (2014-04-05)
The purpose of the study was to evaluate the safety and selectivity of the retinal pigment epithelium lesions by using automatic energy ramping and dosimetry technique for selective retina therapy and to investigate the healing response. Ten eyes of Chinchilla
Wenfang Lai et al.
Neurotoxicity research, 28(2), 108-121 (2015-04-26)
Salidroside exhibits anti-inflammatory, anti-oxidative, and anti-apoptotic properties. To identify whether salidroside might be a candidate for treating ischemic stroke, we investigated the effects of salidroside or vehicle, given daily for 6 days, after middle cerebral artery occlusion (MCAO) for 2
T Ernst et al.
Journal of magnetic resonance imaging : JMRI, 12(6), 859-865 (2000-12-06)
Human immunodeficiency virus-cognitive motor complex (HIV-CMC), a common complication of the acquired immunodeficiency syndrome (AIDS), is characterized by progressive cognitive impairment and motor dysfunction. Functional imaging methods, such as single-photon emission computed tomography (SPECT) and proton magnetic resonance spectroscopy ((1)H-MRS)
Susen Hartmann et al.
Clinical chemistry, 52(6), 1127-1137 (2006-04-15)
Clinical presentation and disease severity in disorders of purine and pyrimidine metabolism vary considerably. We present a method that allows comprehensive, sensitive, and specific diagnosis of the entire spectrum of abnormalities in purine and pyrimidine metabolism in 1 analytical run.
Danbi Lee et al.
Ecotoxicology and environmental safety, 182, 109457-109457 (2019-07-28)
Siloxanes have been used as chemical additives in various products since the 1940s. They are known to have potentially toxic effects, to be environmentally persistent, and to be bioaccumulative. Previous studies have reported high levels of siloxanes in various environmental
Wenli Gu et al.
The Journal of physiology, 539(Pt 3), 657-668 (2002-03-19)
Two novel alternatively spliced isoforms of the human two-pore-domain potassium channel TREK-2 were isolated from cDNA libraries of human kidney and fetal brain. The cDNAs of 2438 base pairs (bp) (TREK-2b) and 2559 bp (TREK-2c) encode proteins of 508 amino
Martin Anlauf et al.
The American journal of surgical pathology, 33(3), 339-346 (2008-11-18)
Multicentric insulinoma disease was characterized with regard to its histopathology, multiple endocrine neoplasia type 1 (MEN1) status, precursor lesions, and the risk of hyperinsulinemic hypoglycemia recurrence. Fourteen patients with multicentric insulinoma disease were compared with 267 patients with sporadic and
Xu-Liang Cao et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 33(2), 373-382 (2016-01-06)
Volatile organic compounds (VOCs) are ubiquitous in the environment due to evaporation and incomplete combustion of fuels, use of consumer and personal care products, etc. and they can accumulate in foods. Some VOCs in foods can also be formed during
Gerald Wischer et al.
Archives of animal nutrition, 67(3), 219-234 (2013-05-18)
The objective of the study was to investigate the effects of monensin on silage fermentation and microbial net protein synthesis. In Experiment 1, monensin (0.5, 1, 2, 4, 6, or 10 µg) was added to syringes that contained 120 mg
Jesse Lopes da Silva et al.
Breast cancer (Dove Medical Press), 13, 31-44 (2021-01-21)
This study aimed to investigate the influence of immunohistochemical (IHC) biomarkers in the response to neoadjuvant chemotherapy (NACT) and survival outcomes in the subset of locally advanced triple-negative breast cancer (TNBC). The epidermal growth factor receptor (EGFR), androgen receptor (AR)
W Berger
Acta anatomica, 162(2-3), 95-100 (1998-12-01)
Norrie disease (ND) is a severe form of congenital blindness accompanied by mental retardation and/or deafness in at least one third of the patients. This article summarizes advances in the molecular genetic analysis of this disease during the last 13
Weidong Wang et al.
American journal of physiology. Renal physiology, 294(6), F1473-F1480 (2008-04-25)
The effect of endotoxemia (lipopolysaccharide, 2.5 mg/kg ip) was investigated in aquaporin (AQP) 1 knockout (KO) compared with wild-type (WT) mice. At baseline, KO mice exhibited higher water intake (WI) and urine output (UO). After endotoxemia, WI and UO remained
M Haq et al.
Journal of the American Society of Nephrology : JASN, 9(4), 614-619 (1998-04-29)
Interleukin-1 (IL-1) is a central component of many acute inflammatory processes. Blocking IL-1 receptor (IL-1R) with IL-1R antagonist (IL-1Ra) has attenuated ischemic reperfusion injury in brain, heart, and liver models. However, the role of IL-1 in renal ischemic reperfusion injury
E Bolognesi et al.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics, 28(5), 523-530 (2002-03-08)
The present study is a contribution to the definition of the linkage disequilibrium relationship of MICA and MICB with adjacent loci and to the characterization of extended HLA haplotypes. These issues are of importance for the identification of disease associations
M Gupta et al.
Annals of the New York Academy of Sciences, 1037, 138-144 (2005-02-09)
Type 1 diabetes mellitus (T1DM) is an autoimmune disease known to occur in genetically susceptible individuals after exposure to certain unknown environmental factors. HLA-DR3-DQ2 or DR4-DQ8 are established genetic markers for the disease. MHC class I chain-related gene-A (MICA) gene
C W Pumphrey et al.
The American journal of cardiology, 50(6), 1258-1261 (1982-12-01)
The plasma concentration of beta-thromboglobulin (BTG), a platelet-specific protein released during platelet aggregation, is considered a sensitive marker of in vivo platelet activity. The mean plasma level in 133 asymptomatic individuals was 32.3 +/- 1.1 ng/ml, and there was no
REEP1 mutation spectrum and genotype/phenotype correlation in hereditary spastic paraplegia type 31.
Christian Beetz et al.
Brain : a journal of neurology, 131(Pt 4), 1078-1086 (2008-03-07)
Mutations in the receptor expression enhancing protein 1 (REEP1) have recently been reported to cause autosomal dominant hereditary spastic paraplegia (HSP) type SPG31. In a large collaborative effort, we screened a sample of 535 unrelated HSP patients for REEP1 mutations
Vyacheslav A Adarichev et al.
Arthritis and rheumatism, 48(6), 1708-1720 (2003-06-10)
To explore the effect of sex on clinical and immunologic traits in major histocompatibility complex-matched (H-2d) F(2) hybrid mice with proteoglycan (PG)-induced arthritis and to identify how the quantitative trait locus (QTL) on the X chromosome influences the onset QTL
Jennifer A Boylston et al.
Journal of molecular and cellular cardiology, 88, 73-81 (2015-09-22)
Succinylation refers to modification of lysine residues with succinyl groups donated by succinyl-CoA. Sirtuin5 (Sirt5) is a mitochondrial NAD(+)-dependent deacylase that catalyzes the removal of succinyl groups from proteins. Sirt5 and protein succinylation are conserved across species, suggesting functional importance
Guido Marcucci et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 28(14), 2348-2355 (2010-04-07)
PURPOSE To analyze the frequency and associations with prognostic markers and outcome of mutations in IDH genes encoding isocitrate dehydrogenases in adult de novo cytogenetically normal acute myeloid leukemia (CN-AML). PATIENTS AND METHODS Diagnostic bone marrow or blood samples from
Anna Axelsson et al.
The lancet. Diabetes & endocrinology, 3(2), 123-131 (2014-12-24)
No medical treatment has been reliably shown to halt or reverse disease progression in hypertrophic cardiomyopathy, but the results of several pilot studies have suggested beneficial effects of angiotensin II receptor blockers on left ventricular hypertrophy and fibrosis, which are
Desy Salvadego et al.
The Journal of physiology, 596(15), 3341-3355 (2018-04-18)
Superposition of hypoxia on 21 day bed rest did not worsen the impairment of skeletal muscle oxidative function induced by bed rest alone. A significant impairment of maximal oxidative performance was identified downstream of cardiovascular O2 delivery, involving both the intramuscular
Janet A Weigel et al.
The Journal of biological chemistry, 278(44), 42802-42811 (2003-08-23)
Hyaluronan (HA) and chondroitin sulfate (CS) clearance from lymph and blood in mammals is mediated by the HA receptor for endocytosis (HARE), which is present as two isoforms in rat and human (175/300 kDa and 190/315 kDa, respectively) in the
Mario Cozzolino et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 24(7), 2207-2212 (2009-02-18)
Vascular calcification and accelerated atherosclerosis are major causes of death in haemodialysis (HD) patients. Matrix metalloproteinases (MMPs) are a family of enzymes, involved in the biology of extracellular matrix and in atherogenesis. MMP1 and MMP3 contribute to the enlargement and
T F Holth et al.
Aquatic toxicology (Amsterdam, Netherlands), 90(4), 277-291 (2008-10-31)
The main effluent from oil and gas production is produced water (PW), a waste that contains low to moderate concentrations of oil-derived substances such as polycyclic aromatic hydrocarbons (PAHs) and alkylphenols (APs). PW components may be present in seawater at
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