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Showing 1-24 of 24 results for "138-15-8" within Papers
H-W Park et al.
Allergy, 64(5), 778-783 (2009-02-03)
Recent findings have raised new interests about the use of anticholinergics, especially tiotropium, for the treatment of asthma. This study was performed to determine whether an additional improvement in lung function is obtained when tiotropium is administrated in addition to
S Oh-hashi et al.
Journal of human hypertension, 6(1), 71-74 (1992-02-01)
To investigate the role of cytosolic free calcium, [Ca2+]i, in secondary hypertension, the levels in platelets from 14 secondary hypertensives (7 renovascular hypertension, 7 primary aldosteronism) were compared with those from 21 essential hypertensives and 15 normotensives by means of
Roberto Fogari et al.
Expert opinion on pharmacotherapy, 14(4), 371-384 (2013-02-19)
The aim was to compare the antiproteinuric effect of aliskiren and ramipril in hypertensive patients with type 2 diabetes and microalbuminuria. A total of 138 patients were treated with aliskiren 300 mg/day or ramipril 10 mg/day for 12 weeks and
Aman U Buzdar et al.
The Lancet. Oncology, 14(13), 1317-1325 (2013-11-19)
Neoadjuvant chemotherapy with trastuzumab for patients with HER2-positive breast cancer can produce a pathological complete response in the breast in 30-65% of patients. We investigated the effect of the timing of trastuzumab administration with anthracycline and taxane neoadjuvant chemotherapy. This
De-zhao Liu et al.
Zhonghua yi xue za zhi, 92(37), 2597-2600 (2013-01-08)
To explore the effects of cromolyn sodium (CS) on intestinal ischemia-reperfusion (IIR) and its relationship with mast cell activation and protease-activated receptor 2 (PAR-2) expression. A total of 32 SD rats were randomly divided into 4 groups: sham-operated (S), intestinal
John R Barbour et al.
The Journal of thoracic and cardiovascular surgery, 132(4), 788-795 (2006-09-27)
An important component of matrix remodeling during thoracic aortic aneurysm progression is the balance between matrix metalloproteinases and their endogenous inhibitors (tissue inhibitors of metalloproteinases). However, whether and to what degree matrix metalloproteinase/tissue inhibitor of metalloproteinases profiles change over time
Gisele C Vaz et al.
Journal of neuroscience methods, 273, 55-63 (2016-10-25)
Liposomes are concentric lipid vesicles that allow a sustained release of entrapped substances. GABA (γ-aminobutyric acid) is the most prevalent inhibitory neurotransmitter in the central nervous system. Using GABA-containing liposomes (GL) prepared by the freeze-thawing method, we determined the effect
Zhenyu Shen et al.
International journal of molecular medicine, 40(1), 193-200 (2017-05-24)
Altered microRNA (miRNA or miR) expression has been reported in chronic obstructive pulmonary disease (COPD). The present study aimed to identify the involvement of miRNAs in the pathophysiology of COPD and to explore the effects of various miRNAs with significant
Bas van den Bogaard et al.
American journal of hypertension, 26(4), 574-579 (2013-03-08)
Sodium nitroprusside (SNP) and labetalol are recommended for the immediate treatment of malignant hypertension. Both are intravenous agents but have different effects on systemic hemodynamics, and may have differential effects on pulse-wave reflection and pulse-pressure amplification, with consequences for peripheral
Lourdes Loidi et al.
Clinical endocrinology, 64(3), 330-336 (2006-02-21)
To detect common as well as rare and novel CYP21A mutations in 21-hydroxylase deficiency patients. To estimate the distribution of mutations and compare them with other European studies. To construct haplotypes linked to a recurrent novel mutation. Genetic analysis by
S N Mitra et al.
Biopolymers, 34(9), 1139-1143 (1994-09-01)
The crystal structure of a dipeptide L-leucyl-L-leucine (C12H24N2O3) has been determined. The crystals are monoclinic, space group P2(1), with a = 5.434(4) A, b = 15.712(7) A, c = 11.275(2) A, beta = 100.41(1) degrees, and Z = 2. The
Wendelin Moser et al.
The Lancet. Infectious diseases, 18(7), 729-737 (2018-04-21)
Albendazole and mebendazole are commonly used to control hookworm, but have shortcomings in their efficacy profiles. We assessed whether triple drug therapy (TDT) with albendazole, pyrantel pamoate, and oxantel pamoate was more effective than the co-administration of two drugs for
J Aravindakshan et al.
Molecular and cellular endocrinology, 329(1-2), 37-46 (2010-07-10)
Among gynecologic malignancies ovarian cancer is the deadliest and most difficult to detect at early stages. As ovarian tumors have long latency and are relatively more frequent in postmenopausal women, revealing chronological changes in model systems might help in the
Masataka Kuwana et al.
The Journal of rheumatology, 30(11), 2392-2397 (2003-12-17)
To examine HLA class II gene associations with anti-RNA polymerase (RNAP) I/III antibody responses in patients with systemic sclerosis (SSc). HLA-DRB1, DRB3, DRB4, and DQB1 alleles were determined using polymerase chain reaction-based methods in 257 SSc patients (129 Japanese and
John S Ikonomidis et al.
Circulation, 112(9 Suppl), I242-I248 (2005-09-15)
The matrix metalloproteinases (MMPs) contribute to cardiovascular remodeling, and MMPs, such as the gelatinases (MMP-9 and MMP-2), have been identified in thoracic aortic aneurysmal (TAA) tissue, but a cause-effect relationship has not been clearly established. Accordingly, this study examined TAA
H R Lijnen et al.
Circulation research, 85(12), 1186-1191 (1999-12-11)
The hypothesis that tissue inhibitor of metalloproteinases-1 (TIMP-1) plays a role in neointima formation was tested with the use of a vascular injury model in wild-type (TIMP-1(+/+)) and TIMP-1-deficient (TIMP-1(-/-)) mice. The neointimal area at 1 to 3 weeks after
Jian Wang et al.
American journal of physiology. Gastrointestinal and liver physiology, 284(6), G1074-G1083 (2003-05-09)
Transient receptor potential channel (TRPC) genes encode Ca(2+)-permeable channels mediating capacitative Ca(2+) entry (CCE), which maintains intracellular Ca(2+) stores. We compared TRPC gene expression and CCE in human esophageal body (EB) and lower esophageal sphincter (LES), because these smooth muscles
T M Reshetniak et al.
Terapevticheskii arkhiv, 85(1), 76-84 (2013-03-29)
To estimate the prevalence of plasminogen activator inhibitor type 1 (PAI-1) gene polymorphism in patients with antiphospholipid syndrome (APS) and its implication in vascular disorders. The investigation enrolled 138 patients: 103 with APS, including 47 with systemic lupus erythematosus (SLE)
Pierre Miegueu et al.
American journal of physiology. Gastrointestinal and liver physiology, 304(4), G420-G427 (2012-12-22)
Obesity, inflammation, and insulin resistance are closely linked. Substance P (SP), via its neurokinin 1 receptor (NK1R), mediates inflammatory and, possibly, neuroendocrine processes. We examined SP effects on lipid storage and cytokine production in 3T3-L1 adipocytes and adipose tissues. 3T3-L1
K MacKay et al.
Rheumatology (Oxford, England), 42(1), 149-153 (2003-01-02)
IL-10 is an immunoregulatory cytokine which may modulate disease expression in rheumatoid arthritis (RA). The IL-10 gene is highly polymorphic with a number of single nucleotide polymorphisms in the promoter region and two microsatellite loci, IL10.R and IL10.G, 4 kb
Igor Sukhotnik et al.
Pediatric surgery international, 24(1), 21-28 (2007-11-07)
Recent evidence suggests that transforming growth factor alpha (TGF-alpha) enhances enterocyte proliferation and stimulates intestinal adaptation after massive bowel resection. In the present study, we evaluated the effects of TGF-alpha on enterocyte turnover and correlated it with epidermal-growth factor (EGF)
J G Conway et al.
Cancer research, 47(18), 4795-4800 (1987-09-15)
The diffusion of H2O2 into the cytoplasm from peroxisomes during high rates of peroxisomal beta oxidation of fatty acids was studied in perfused livers from rats treated with the hepatocarcinogenic peroxisome proliferator, nafenopin. Efflux of oxidized glutathione (GSSG) into the
Khai Li Chai et al.
The Cochrane database of systematic reviews, 10, CD013600-CD013600 (2020-10-13)
Convalescent plasma and hyperimmune immunoglobulin may reduce mortality in patients with viral respiratory diseases, and are currently being investigated in trials as potential therapy for coronavirus disease 2019 (COVID-19). A thorough understanding of the current body of evidence regarding the benefits
Farid E Ahmed et al.
Cancer genomics & proteomics, 10(3), 93-113 (2013-06-07)
To present proof-of-principle application for employing micro(mi)RNAs as diagnostic markers for colon cancer, we carried out global microarray expression studies on stool samples obtained from fifteen individuals (three controls, and three each with TNM stage 0-1, stage 2, stage 3
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