Sherif Z Abdel-Rahman et al.
Environmental and molecular mutagenesis, 41(2), 140-146 (2003-02-28)
The carcinogenic effects of 1,3-butadiene (BD), a chemical widely used in the rubber industry, are thought to be due to its epoxide metabolites. In humans, these epoxides are detoxified predominantly by hydrolysis, a reaction mediated by the microsomal epoxide hydrolase