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Showing 31-56 of 56 results for "141-24-2" within Papers
Yunjie Wang et al.
Antioxidants & redox signaling, 28(2), 141-163 (2017-07-28)
Microglia-mediated neuroinflammation plays an important role in focal ischemic stroke, a disorder with no effective therapeutic agents. Since microglial polarization to the M2 phenotype and reduction of oxidative stress are mediated through AMP-activated protein kinase (AMPK) and nuclear factor erythroid
Sima L Sharara et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71(8), e331-e337 (2019-12-21)
Limited data exist regarding the efficacy of piperacillin-tazobactam (TZP) for the management of nonbacteremic pyelonephritis caused by extended-spectrum β-lactamase (ESBL)-producing organisms. We conducted a multicenter observational study comparing clinical outcomes of adults hospitalized with ESBL-producing pyelonephritis who were receiving TZP
Zelda Kilbane et al.
Molecular and cellular biochemistry, 297(1-2), 189-197 (2006-11-23)
We describe the cloning, expression and purification of the bovine XM866409 form of pyroglutamyl peptidase type-1 (PAP1). The cloned nucleotide sequence has an ORF coding for a primary sequence of 209 amino acid residues, which displays 98% identity with the
L K Philp et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 295(6), R1982-R1990 (2008-09-12)
Epidemiological studies have shown that infants exposed to an increased supply of nutrients before birth are at increased risk of type 2 diabetes in later life. We have investigated the hypothesis that fetal overnutrition results in reduced expression and phosphorylation
Jan Tack et al.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 10(11), 1239-1245 (2012-07-21)
Impaired accommodation and hypersensitivity to gastric distention are believed to be involved in the development of functional dyspepsia (FD). Buspirone, a 5-hydroxytryptamine 1A receptor agonist, relaxes the proximal stomach in healthy individuals. We studied the effects of buspirone on symptoms
Sales Ibiza et al.
American journal of physiology. Cell physiology, 297(6), C1588-C1595 (2009-10-09)
Gastric mucosal inflammation is frequently associated with hypergastrinemia, and a correlation exists between the level of gastrin and degree of gastritis. We have previously observed that gastrin promotes leukocyte-endothelial interactions and contributes to Helicobacter-induced inflammation in the rat mesentery. In
C Flummer et al.
Journal of animal science, 90 Suppl 4, 372-374 (2013-02-13)
This trial was conducted to investigate whether β-hydroxy β-methyl butyrate (HMB) supplementation during late gestation and throughout lactation would influence colostrum and milk production of sows and neonatal piglet survival (0 to 24 h). Control sows (CON; n = 8)
Christopher A Peters et al.
International journal of radiation oncology, biology, physics, 70(3), 752-759 (2007-08-11)
To investigate whether the presence of single nucleotide polymorphisms (SNPs) located within TGFB1 might be predictive for the development of adverse quality-of-life outcomes in prostate cancer patients treated with radiotherapy. A total of 141 prostate cancer patients treated with radiotherapy
G Falkson et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 16(5), 1669-1676 (1998-05-20)
To investigate the value of maintenance treatment for patients with metastatic breast cancer whose disease is in complete remission (CR). One hundred ninety-five women (141 eligible) whose disease was in CR or in CR except for bone metastases following six
M Saegusa et al.
British journal of cancer, 84(2), 209-217 (2001-02-13)
To clarify the possible role of aberrant beta-catenin expression during endometrial tumorigenesis, a total of 199 cases of endometrial carcinomas (endometrioid type), as well as 37 cases of simple/complex and 32 of atypical hyperplasias, was consecutively investigated for immunohistochemistry, along
Li Xiao et al.
Zhonghua yi xue za zhi, 91(8), 512-515 (2011-03-23)
To find whether the up-regulation of soluble human leucocyte antigen-G5 (sHLA-G5) levels is a new function mechanism of anti-interleukin-2 receptors (anti-IL-2R) monoclonal antibody treatment in kidney transplantation. A total of 215 recipients at our centre from January 2006 to December
Wei Liu et al.
The Prostate, 80(8), 609-618 (2020-03-14)
Using a functional analysis of prostate cancer cells, we found a CD24-dependent inactivation of mutant p53, but the clinical significance of this observation remained uncertain. Here, we validated these results with samples of human prostate cancer and explored the role
Bing-Yang Chai et al.
Evidence-based complementary and alternative medicine : eCAM, 2020, 1986962-1986962 (2020-02-28)
In traditional Chinese medicine (TCM), chronic myeloid leukemia (CML) has been attributed to "poisoned bone marrow," which is viewed as a loss of Qi or blood, a deficiency in Yin or Yang that causes a complex imbalance between cell growth
Jianhui Zhang et al.
Carcinogenesis, 24(5), 905-909 (2003-05-29)
NAD(P)H: quinone oxidoreductase 1 (NQO1) is an antioxidant enzyme, important in the detoxification of environmental carcinogens. A single base substitution (C --> T) polymorphism at nucleotide 609 (null-allele) of NQO1 gene impairs stability and function of the NQO1 protein. To
S Rodenhuis et al.
Cancer research, 52(9 Suppl), 2665s-2669s (1992-05-01)
Activation of ras oncogenes is commonly found in human neoplasms. We have investigated 280 human lung cancer specimens for ras activation, including 38 that have not been reported previously, using an oligonucleotide detection assay. From a total of 141 adenocarcinoma
John A Thompson et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 24(18), 4399-4406 (2018-06-01)
Purpose: To determine the safety, pharmacokinetics, and recommended phase II dose of an antibody-drug conjugate (ADC) targeting ectonucleotide phosphodiesterases-pyrophosphatase 3 (ENPP3) conjugated to monomethyl auristatin F (MMAF) in subjects with advanced metastatic renal cell carcinoma (mRCC).Patients and Methods: Two phase
Eva Marie Quijano Cardé et al.
Frontiers in veterinary science, 7, 587952-587952 (2020-11-17)
Cyprinid Herpesvirus 3 (CyHV-3), more commonly known as Koi Herpesvirus (KHV), is a re-emergent virus causing acute systemic infection with high mortality rates in koi fish (Cyprinus carpio). Survivors from outbreaks can become latent carriers, with viral reactivation under stressful
Maya Ghoussaini et al.
The Journal of clinical endocrinology and metabolism, 92(11), 4403-4409 (2007-08-19)
The melanin-concentrating hormone receptor 2 (MCHR2) is a G protein-coupled receptor for melanin-concentrating hormone, a neuropeptide that plays an important role in feeding behaviors. MCHR2 maps on chromosome 6q16.3, in a susceptibility locus for childhood obesity. The aim of this
Hidehiko Watanabe et al.
American journal of dentistry, 26(5), 265-270 (2014-02-01)
To evaluate the mechanical strength and color stability of provisional restoration materials. For mechanical testing, four groups [Trim (PEMA), Alike (PMMA), Versatemp (bis-acrylic resin composite, BARC) and Perfectemp II (bis-acrylic fluoride enriched resin, BAFC)] of resin disks were prepared for
R A Nowak et al.
Biology of reproduction, 60(1), 85-93 (1998-12-22)
The goals of this study were 1) to compare the effects of transforming growth factor-beta (TGF-beta) and parathyroid hormone-related protein (PTHrP) on mouse blastocyst attachment and outgrowth in vitro, 2) to determine whether TGF-beta acts through a mechanism involving PTHrP
Hong Zheng et al.
BioMed research international, 2020, 4951692-4951692 (2020-03-10)
Wilms' tumor (WT) is the most common type of childhood kidney cancer, and most cases present with favorable histology and respond well to standard treatment. However, a subset of patients with WT is diagnosed with bilateral, relapsed, and high-risk tumors
Fiona V Cresswell et al.
The Lancet. Infectious diseases, 20(3), 308-317 (2020-01-12)
Tuberculous meningitis accounts for 1-5% of tuberculosis cases. Diagnostic delay contributes to poor outcomes. We evaluated the performance of the new Xpert MTB/RIF Ultra (Xpert Ultra) for tuberculous meningitis diagnosis. In this prospective validation study, we tested the cerebrospinal fluid
Volkmar Lufft et al.
European radiology, 12(4), 804-809 (2002-04-18)
The aim of this study was to compare renal function between patients with renal angiography and patients with renal angiography and angioplasty (AP) for renal artery stenosis (RAS). Forty-seven patients with suspected RAS were prospectively investigated by digital subtraction angiography
Steven S Shen et al.
Cancer, 106(12), 2610-2616 (2006-05-16)
Estrogen receptors (ERs) are known to mediate important physiologic responses as well as the growth of some tumors in response to estradiol stimulation. In a previous study the selective ER modulator raloxifene was shown to induce apoptosis in an ERbeta-positive
Manuel Valladares-Ayerbes et al.
Journal of translational medicine, 10, 186-186 (2012-09-08)
MicroRNAs are aberrantly expressed and correlate with tumourigenesis and the progression of solid tumours. The miR-200 family determines the epithelial phenotype of cancer cells and regulates invasiveness and migration. Thus, we hypothesised that the quantitative detection of the miR-200 family
Bardia Nourbakhsh et al.
The Lancet. Neurology, 20(1), 38-48 (2020-11-27)
Methylphenidate, modafinil, and amantadine are commonly prescribed medications for alleviating fatigue in multiple sclerosis; however, the evidence supporting their efficacy is sparse and conflicting. Our goal was to compare the efficacy of these three medications with each other and placebo
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