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Showing 1-18 of 18 results for "142-63-2" within Papers
N Zhang et al.
Genesis (New York, N.Y. : 2000), 27(4), 137-140 (2000-09-19)
Phosphatidic acid phosphatases (PAPs) catalyze the conversion of phosphatidic acid to diacylglycerol and inorganic phosphate and have been postulated to function both in lipid biosynthesis and in cellular signal transduction. In Drosophila melanogaster, the Type 2 phosphatidic acid phosphatase protein
Sylvie Lalonde et al.
Frontiers in physiology, 1, 24-24 (2010-01-01)
Interactions between membrane proteins and the soluble fraction are essential for signal transduction and for regulating nutrient transport. To gain insights into the membrane-based interactome, 3,852 open reading frames (ORFs) out of a target list of 8,383 representing membrane and
Kentaro Oniki et al.
Toxicology letters, 178(3), 143-145 (2008-04-24)
Glutathione S-transferases protect cells against exogenous and endogenous oxidative stress. Type 2 diabetes is associated with an increased production of reactive oxygen species and a reduction in antioxidant defenses. This study investigated whether GSTA1*A/*B and GSTP1Ile105Val polymorphisms could affect the
Javier Zarranz-Ventura et al.
American journal of ophthalmology, 158(6), 1136-1145 (2014-09-15)
To identify clinical outcomes and treatment patterns of intravitreal dexamethasone implant (Ozurdex; Allergan, Inc) in noninfectious uveitis in the clinical setting. Multicenter retrospective cohort study. Eighty-two eyes (63 patients) receiving 142 implant injections over 35 months were included. Treatment indication
Moïse Coëffier et al.
Cytokine, 18(2), 92-97 (2002-07-05)
Glutamine modulates cytokine production in various tissues but its effects on the production of other inflammatory mediators such as eicosanoids and nitric oxide have not been investigated in human gut. To evaluate the influence of glutamine on interleukin (IL)-8, IL-6
H Kremling et al.
Biochimica et biophysica acta, 1132(2), 133-139 (1992-09-24)
Protamine 2 (PRM2) is a low molecular weight arginine-rich protein which is present in haploid spermatogenic cells of human and mouse. Although the bull PRM2 gene is translated and transcribed at low levels, the protein could not be detected. The
Haitham Khogeer et al.
British journal of haematology, 186(4), 538-548 (2019-05-23)
The differential immunophenotypic characteristics of early T precursor (ETP) acute lymphoblastic leukaemia/lymphoma (ALL) remain incompletely characterized. The study group (n = 142) included 106 (74·7%) men and 36 (25·3%) women with a median age of 34·9 years (range, 2-79) at diagnosis. Patients were
G Wong et al.
Biochemistry, 26(26), 8683-8690 (1987-12-29)
The cDNA clone p16 alpha-1 for the male-specific isozyme (C-P-450(16) alpha)1 of testosterone 16 alpha-hydroxylase in livers of 129/J mice [Harada, N., & Negishi, M. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 2024-2028] and two additional full-length cDNAs overlapping with
Glenda Courtney-Martin et al.
JPEN. Journal of parenteral and enteral nutrition, 39(5), 578-585 (2014-04-20)
Patients receiving long-term parenteral nutrition (PN) are at increased risk of aluminium (Al) toxicity because of bypass of the gastrointestinal tract during PN infusion. Complications of Al toxicity include metabolic bone disease (MBD), Al-associated encephalopathy in adults, and impaired neurological
Philipp Erben et al.
Annals of hematology, 93(1), 81-88 (2013-11-28)
The activating KIT D816V mutation plays a central role in the pathogenesis, diagnosis, and targeted treatment of systemic mastocytosis (SM). For improved and reliable identification of KIT D816V, we have developed an allele-specific quantitative real-time PCR (RQ-PCR) with an enhanced
Amanda Rewers et al.
Annals of the New York Academy of Sciences, 1005, 301-309 (2003-12-18)
The HLA genotype DRB1*03,DQB1*0201/DRB1*04,DQB1*0302 confers a 25-fold increase in the risk of type 1 diabetes. In persons with this genotype, DRB1*0405, *0402, and *0401 subtypes have been reported to further increase risk, whereas the *0403 and *0406 alleles confer a
Christian Bruch et al.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 25(9), 1135-1141 (2006-09-12)
In patients with chronic heart failure (CHF), N-terminal pro-brain natriuretic peptide (NT-proBNP) provides relevant prognostic information, but its usefulness in the presence of kidney disease has been questioned. We prospectively enrolled 142 patients with stable CHF and a wide spectrum
Michael R Fettiplace et al.
Anesthesiology, 124(2), 428-442 (2015-12-10)
The impact of local anesthetics on the regulation of glucose homeostasis by protein kinase B (Akt) and 5'-adenosine monophosphate-activated protein kinase (AMPK) is unclear but important because of the implications for both local anesthetic toxicity and its reversal by IV
Aaron J Polichnowski et al.
American journal of physiology. Renal physiology, 309(9), F791-F799 (2015-06-26)
The diet-induced obesity (DIO) model is frequently used to examine the pathogenesis of obesity-related pathologies; however, only minimal glomerulosclerosis (GS) has been reported after 3 mo. We investigated if GS develops over longer periods of DIO and examined the potential
Alanna Mara Pinheiro Sobreira Bezerra et al.
Einstein (Sao Paulo, Brazil), 9(2), 151-159 (2011-06-01)
To demonstrate the advantages of correlating flow cytometry immunophenotyping with the pathology/ immunohistochemistry of lymph nodes or nodules in the diagnosis of lymphoproliferative diseases. A retrospective study was carried out of 157 biopsy or fine-needle aspiration lymph nodes/ nodule specimens
Pierre Pasquier et al.
Anesthesia and analgesia, 116(1), 155-161 (2012-12-12)
Postpartum hemorrhage is the leading cause of maternal death worldwide. Recent data from trauma patients and patients with hemorrhagic shock have suggested that an increased fresh frozen plasma:red blood cell (FFP:RBC) ratio may be of benefit in massive bleeding. We
Zhi-hong Wang et al.
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 28(11), 755-759 (2005-12-06)
To investigate the expression of vascular endothelial growth factor (VEGF) and the effect of a VEGF receptor inhibitor on airway inflammation and remodeling in a murine model of asthma. BALB/c mice were randomly divided into three groups: group A (control
David J Tunnicliffe et al.
The Cochrane database of systematic reviews, 6, CD002922-CD002922 (2018-06-30)
Cyclophosphamide, in combination with corticosteroids, has been first-line treatment for inducing disease remission for proliferative lupus nephritis, reducing death at five years from over 50% in the 1950s and 1960s to less than 10% in recent years. Several treatment strategies
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