1432005

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Showing 1-29 of 29 results for "1432005" within Papers

Smart Soup, a traditional Chinese medicine formula, ameliorates amyloid pathology and related cognitive deficits.

Yujun Hou et al.

PloS one, 9(11), e111215-e111215 (2014-11-12)

Alzheimer's disease (AD) is a progressive neurodegenerative disease that causes substantial public health care burdens. Intensive efforts have been made to find effective and safe disease-modifying treatment and symptomatic intervention alternatives against AD. Smart Soup (SS), a Chinese medicine formula

Selective retention of basic compounds by metal aquo-ion affinity chromatography.

Yoshiki Asakawa et al.

Journal of separation science, 37(19), 2641-2651 (2014-07-22)

A novel metal aquo-ion affinity chromatography has been developed for the analysis of basic compounds using heat-treated silica gel containing hydrated metal cations (metal aquo-ions) as the packing material. The packing materials of the metal aquo-ion affinity chromatography were prepared

Evaluation of the health aspects of methyl paraben: a review of the published literature.

M G Soni et al.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 40(10), 1335-1373 (2002-10-22)

Methyl paraben (CAS No. 99-76-3) is a methyl ester of p-hydroxybenzoic acid. It is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics for over 50 years. Methyl paraben is readily and completely absorbed through

Localization of sunitinib in in vivo animal and in vitro experimental models by MALDI mass spectrometry imaging.

James J Connell et al.

Analytical and bioanalytical chemistry, 407(8), 2245-2253 (2014-11-27)

The spatial distribution of an anticancer drug and its intended target within a tumor plays a major role on determining how effective the drug can be at tackling the tumor. This study provides data regarding the lateral distribution of sunitinib

Use of topical liposomes containing meglumine antimoniate (Glucantime) for the treatment of L. major lesion in BALB/c mice.

S A Moosavian Kalat et al.

Experimental parasitology, 143, 5-10 (2014-05-02)

Treatment of cutaneous leishmaniasis (CL) is a dream for the patients, health care authorities and scientists. The aim of this study was to develop a topical liposomal meglumine antimoniate (MA, Glucantime™) (Lip-MA) formulation and evaluate the therapeutic effects of the

Determination and separation of bisphenol A, phthalate metabolites and structural isomers of parabens in human urine with conventional high-pressure liquid chromatography combined with electrospray ionisation tandem mass spectrometry.

Antonis Myridakis et al.

Analytical and bioanalytical chemistry, 407(9), 2509-2518 (2015-02-04)

Phthalates, bisphenol A (BPA) and parabens (PBs), organic chemicals widely used in everyday products, are considered to be endocrine disruptors. We propose a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of seven phthalate metabolites, six PBs and BPA

In vivo evaluation of anticonvulsant and antioxidant effects of phenobarbital microemulsion for transdermal administration in pilocarpine seizure rat model.

Kayo Alves Figueiredo et al.

Pharmacology, biochemistry, and behavior, 131, 6-12 (2015-01-27)

This study aimed to evaluate a microemulsion system (ME) containing phenobarbital in epilepsy model induced by pilocarpine in rats and to oxidative stress and histologic lesions in hippocampus. The microemulsion was applied to the shaved back of Wistar rats. The

Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream.

Andreas Lauterbach et al.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(3), 614-624 (2014-12-03)

A novel adapalene-loaded solid lipid microparticle (SLMA) dispersion as a topical drug delivery system (TDDS) for follicular penetration has been introduced. The objective of the present study was to investigate the rheological properties, the follicular penetration with differential tape stripping

Analysis of endocrine disrupters and related compounds in sediments and sewage sludge using on-line turbulent flow chromatography-liquid chromatography-tandem mass spectrometry.

Marina Gorga et al.

Journal of chromatography. A, 1352, 29-37 (2014-06-10)

A novel fully automated method based on dual column switching using turbulent flow chromatography followed by liquid chromatography coupled to tandem mass spectrometry (TFC-LC-MS/MS) was applied for the determination of endocrine disruptors (EDCs) and related compounds in sediment and sewage

Dexamethasone Oral Solution

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 43(6), 1288-1288 (2014)

Ethylparaben Sodium

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 41(1), 5773-5773 (2016)

Mixture effects at very low doses with combinations of anti-androgenic pesticides, antioxidants, industrial pollutant and chemicals used in personal care products.

Frances Orton et al.

Toxicology and applied pharmacology, 278(3), 201-208 (2013-09-24)

Many xenobiotics have been identified as in vitro androgen receptor (AR) antagonists, but information about their ability to produce combined effects at low concentrations is missing. Such data can reveal whether joint effects at the receptor are induced at low

Prophylactic treatment with a novel bioadhesive gel formulation containing aciclovir and tenofovir protects from HSV-2 infection.

Gita N Shankar et al.

The Journal of antimicrobial chemotherapy, 69(12), 3282-3293 (2014-08-21)

Over-the-counter access to an inexpensive, effective topical microbicide could reduce the transmission of HIV and would increase women's control over their health and eliminate the need to obtain their partners' consent for prophylaxis. Chronic infection with herpes simplex virus 2

New topical photodynamic therapy for treatment of hidradenitis suppurativa using methylene blue niosomal gel: a single-blind, randomized, comparative study.

M A Fadel et al.

Clinical and experimental dermatology, 40(2), 116-122 (2014-09-30)

Hidradenitis suppurativa (HS), is a chronic, recurrent dermatosis affecting skin that contains apocrine glands. Photodynamic therapy using aminolaevulinic acid (ALA) activated by intense pulsed light (IPL) have shown variable success rates, with some adverse effects. To evaluate the efficacy and

In vitro and in vivo evaluation of two carrageenan-based formulations to prevent HPV acquisition.

Aixa Rodríguez et al.

Antiviral research, 108, 88-93 (2014-06-10)

Commercial vaccines against human papillomavirus (HPV) have low uptake due to parental autonomy, dosing regimen, cost, and cold chain storage requirements. Carrageenan (CG)-based formulations prevent HPV infection in vitro and in vivo but data are needed on the durability of

High efficiency polyethylene glycol diacrylate monoliths for reversed-phase capillary liquid chromatography of small molecules.

Pankaj Aggarwal et al.

Journal of chromatography. A, 1364, 96-106 (2014-09-07)

Highly cross-linked monolithic networks (i.e., polyethylene glycol diacrylate, PEGDA) synthesized from monomers containing varying ethylene oxide chain lengths were fabricated inside fused silica capillary columns for use in liquid chromatography (LC) of small molecules. Tergitol was used as a surfactant

Antibacterial properties of 2% lidocaine and reduced rate of endophthalmitis after intravitreal injection.

Aaron Tustin et al.

Retina (Philadelphia, Pa.), 34(5), 935-942 (2013-10-10)

To determine whether the application of subconjunctival 2% lidocaine/0.1% methylparaben for anesthesia may reduce rates of endophthalmitis after intravitreal (IVT) injection. We performed in vitro experiments to determine the antibacterial properties of 2% lidocaine/0.1% methylparaben (lidocaine) against causative organisms of

Methylparaben

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 36(5), 5886-5886 (2020)

Screening of bisphenol A, triclosan and paraben analogues as modulators of the glucocorticoid and androgen receptor activities.

Katra Kolšek et al.

Toxicology in vitro : an international journal published in association with BIBRA, 29(1), 8-15 (2014-09-07)

A homeostasis of the glucocorticoid and androgen endocrine system is essential to human health. Their disturbance can lead to various diseases, for example cardiovascular, inflammatory and autoimmune diseases, infertility, cancer. Fifteen widely used industrial chemicals that disrupt endocrine activity were

Ultra-preconcentration and determination of selected pharmaceutical and personal care products in different water matrices by solid-phase extraction combined with dispersive liquid-liquid microextraction prior to ultra high pressure liquid chromatography tandem mass spectrometry analysis.

Rita Celano et al.

Journal of chromatography. A, 1355, 26-35 (2014-06-19)

Pharmaceutical and personal care products (PPCPs) are one of the most important classes of emerging contaminants. The potential of ecological and environmental impacts associated with PPCPs are of particular concern because they continually penetrate the aquatic environment. This work describes

Development and validation of a stability-indicating LC-UV method for the determination of pantethine and its degradation product based on a forced degradation study.

Rossana Canavesi et al.

Journal of pharmaceutical and biomedical analysis, 97, 141-150 (2014-05-28)

Pantethine (d-bis-(N-pantothenyl-β-aminoethyl)-disulfide, PAN), the stable disulfide form of pantetheine, has beneficial effects in vascular diseases being able to decrease the hyperlipidaemia, moderate the platelet function and prevent the lipid peroxidation. Furthermore, recent studies suggested that PAN may be an effective

Actions of methyl-, propyl- and butylparaben on estrogen receptor-α and -β and the progesterone receptor in MCF-7 cancer cells and non-cancerous MCF-10A cells.

Anna Maria Wróbel et al.

Toxicology letters, 230(3), 375-381 (2014-08-17)

Numerous studies have shown that widely used parabens possess estrogenic properties. In the present study, we examined the effects of methyl-, propyl- and butylparaben on the mRNA and protein expression of estrogen receptor (ER)-α (ESR1) and -β (ESR2) and the

The complex contributions of genetics and nutrition to immunity in Drosophila melanogaster.

Robert L Unckless et al.

PLoS genetics, 11(3), e1005030-e1005030 (2015-03-13)

Both malnutrition and undernutrition can lead to compromised immune defense in a diversity of animals, and "nutritional immunology" has been suggested as a means of understanding immunity and determining strategies for fighting infection. The genetic basis for the effects of

Benzaldehyde

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 38(1), 5632-5632 (2020)

Estimation of the effects of longitudinal temperature gradients caused by frictional heating on the solute retention using fully porous and superficially porous sub-2μm materials.

Szabolcs Fekete et al.

Journal of chromatography. A, 1359, 124-130 (2014-07-30)

In this study, the retention changes induced by frictional heating were evaluated for model small compounds (150-190Da) and a small protein, namely insulin (5.7kDa). For this purpose, the effect of longitudinal temperature gradient caused by frictional heating was experimentally dissociated

Plasma-spray ionization (PLASI): a multimodal atmospheric pressure ion source for liquid stream analysis.

Adam Kaylor et al.

Journal of the American Society for Mass Spectrometry, 25(10), 1788-1793 (2014-07-09)

A new ion generation method, named plasma-spray ionization (PLASI) for direct analysis of liquid streams, such as in continuous infusion experiments or liquid chromatography (LC), is reported. PLASI addresses many of the analytical limitations of electrospray ionization (ESI) and has

Methylparaben Sodium

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 39(5), 5887-5887 (2014)

Solid lipid nanoparticles-loaded topical gel containing combination drugs: an approach to offset psoriasis.

Rahul Sonawane et al.

Expert opinion on drug delivery, 11(12), 1833-1847 (2014-08-01)

The primary aim of present work was to develop effective combination drug therapy for topical treatment of psoriasis. Betamethasone dipropionate and calcipotriol loaded solid lipid nanoparticles (CT-BD-SLNs) were prepared by hot melt high shear homogenization technique, which were then incorporated

Determination of preservatives in cosmetics, cleaning agents and pharmaceuticals using fast liquid chromatography.

Irena Baranowska et al.

Journal of chromatographic science, 52(1), 88-94 (2013-01-18)

This paper reports the development of a method for simultaneously determining five preservatives in cosmetics, cleaning agents and pharmaceuticals by fast liquid chromatography. Methylisothiazolinone, methylchloroisothiazolinone, benzyl alcohol, sodium benzoate and methylparaben were separated on a Chromolith Fast Gradient reversed-phase 18e

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