1550001

Applied Filters:

Keyword:'1550001'

Showing 1-20 of 20 results for "1550001" within Papers

Dopamine and norepinephrine receptors participate in methylphenidate enhancement of in vivo hippocampal synaptic plasticity.

Daniel Jenson et al.

Neuropharmacology, 90, 23-32 (2014-12-03)

Attention-deficit hyperactive disorder (ADHD) is the most commonly studied and diagnosed psychiatric disorder in children. Methylphenidate (MPH, e.g., Ritalin) has been used to treat ADHD for over 50 years. It is the most commonly prescribed treatment for ADHD, and in

Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation.

Tricia H Smith et al.

Molecular pharmacology, 87(4), 747-765 (2015-02-07)

Cannabinoid CB1 receptors (CB1Rs) mediate the presynaptic effects of endocannabinoids in the central nervous system (CNS) and most behavioral effects of exogenous cannabinoids. Cannabinoid receptor-interacting protein 1a (CRIP1a) binds to the CB1R C-terminus and can attenuate constitutive CB1R-mediated inhibition of

Peripheral inflammation activated focal adhesion kinase signaling in spinal dorsal horn of mice.

Xia Lian et al.

Journal of neuroscience research, 93(6), 873-881 (2015-01-24)

Focal adhesion kinase (FAK) is one of the nonreceptor protein tyrosine kinases critical for the dynamic regulation of cell adhesion structures. Recent studies have demonstrated that FAK is also localized at excitatory glutamatergic synapses and is involved in long-term modification

Dopamine D1 and D5 receptors modulate spike timing-dependent plasticity at medial perforant path to dentate granule cell synapses.

Kechun Yang et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(48), 15888-15897 (2014-11-28)

Although evidence suggests that DA modulates hippocampal function, the mechanisms underlying that dopaminergic modulation are largely unknown. Using perforated-patch electrophysiological techniques to maintain the intracellular milieu, we investigated how the activation of D1-type DA receptors regulates spike timing-dependent plasticity (STDP)

Potassium Gluconate Tablets

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 40(3), 1122-1122 (2016)

Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.

Julia Hasreiter et al.

American journal of physiology. Cell physiology, 306(12), C1200-C1213 (2014-04-25)

In the central nervous system, L-type voltage-gated calcium channels (LTCCs) come in two isoforms, namely Cav1.2 and Cav1.3 channels. It has been shown previously that these channels differ in biophysical properties, in subcellular localization, and in the coupling to the

Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation.

Annette Ives et al.

Nature communications, 6, 6555-6555 (2015-03-25)

Activation of the NLRP3 inflammasome by microbial ligands or tissue damage requires intracellular generation of reactive oxygen species (ROS). We present evidence that macrophage secretion of IL1β upon stimulation with ATP, crystals or LPS is mediated by a rapid increase

Depression of excitatory synapses onto parvalbumin interneurons in the medial prefrontal cortex in susceptibility to stress.

Zinaida Perova et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(7), 3201-3206 (2015-02-24)

In response to extreme stress, individuals either show resilience or succumb to despair. The prefrontal cortex (PFC) is required for coping with stress, and PFC dysfunction has been implicated in stress-related mental disorders, including depression. Nevertheless, the mechanisms by which

Okibacterium endophyticum sp. nov., a novel endophytic actinobacterium isolated from roots of Salsola affinis C. A. Mey.

Hong-Fei Wang et al.

Antonie van Leeuwenhoek, 107(3), 835-843 (2015-01-09)

A white bacterial strain, designated EGI 650022(T), was isolated from the roots of Salsola affinis C. A. Mey, collected from Urumqi City, Xinjiang, north-western China. The strain was found to be aerobic, Gram-stain positive, oxidase-positive and catalase-positive. Cells were non-motile

Localized adenosine signaling provides fine-tuned negative feedback over a wide dynamic range of neocortical network activities.

Mark J Wall et al.

Journal of neurophysiology, 113(3), 871-882 (2014-11-14)

Although the patterns of activity produced by neocortical networks are now better understood, how these states are activated, sustained, and terminated still remains unclear. Negative feedback by the endogenous neuromodulator adenosine may potentially play an important role, as it can

Conformationally sensitive proximity of extracellular loops 2 and 4 of the γ-aminobutyric acid (GABA) transporter GAT-1 inferred from paired cysteine mutagenesis.

Maram Hilwi et al.

The Journal of biological chemistry, 289(49), 34258-34266 (2014-10-24)

The sodium- and chloride-coupled GABA transporter GAT-1 is a member of the neurotransmitter:sodium:symporters, which are crucial for synaptic transmission. Structural work on the bacterial homologue LeuT suggests that extracellular loop 4 closes the extracellular solvent pathway when the transporter becomes

Ferrous Gluconate Oral Solution

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 28(2), 1860-1860 (2013)

Gastric vagal motoneuron function is maintained following experimental spinal cord injury.

E M Swartz et al.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 26(12), 1717-1729 (2014-10-16)

Clinical reports indicate that spinal cord injury (SCI) initiates profound gastric dysfunction. Gastric reflexes involve stimulation of sensory vagal fibers, which engage brainstem circuits that modulate efferent output back to the stomach, thereby completing the vago-vagal reflex. Our recent studies

Metabolic engineering of Acinetobacter baylyi ADP1 for improved growth on gluconate and glucose.

Matti Kannisto et al.

Applied and environmental microbiology, 80(22), 7021-7027 (2014-09-07)

A high growth rate in bacterial cultures is usually achieved by optimizing growth conditions, but metabolism of the bacterium limits the maximal growth rate attainable on the carbon source used. This limitation can be circumvented by engineering the metabolism of

Ferrous Gluconate Capsules

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 1859-1859 (2013)

Intrinsic neurophysiological properties of hilar ectopic and normotopic dentate granule cells in human temporal lobe epilepsy and a rat model.

A L Althaus et al.

Journal of neurophysiology, 113(4), 1184-1194 (2014-11-28)

Hilar ectopic dentate granule cells (DGCs) are a salient feature of aberrant plasticity in human temporal lobe epilepsy (TLE) and most rodent models of the disease. Recent evidence from rodent TLE models suggests that hilar ectopic DGCs contribute to hyperexcitability

Ferrous Gluconate Tablets

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 1861-1861 (2013)

In vivo two-photon imaging of structural dynamics in the spinal dorsal horn in an inflammatory pain model.

Shinji Matsumura et al.

The European journal of neuroscience, 41(7), 989-997 (2015-02-04)

Two-photon microscopy imaging has recently been applied to the brain to clarify functional and structural synaptic plasticity in adult neural circuits. Whereas the pain system in the spinal cord is phylogenetically primitive and easily exhibits behavioral changes such as hyperalgesia

Disruption of a neural microcircuit in the rod pathway of the mammalian retina by diabetes mellitus.

Áurea Castilho et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(13), 5422-5433 (2015-04-04)

Diabetes leads to dysfunction of the neural retina before and independent of classical microvascular diabetic retinopathy, but previous studies have failed to demonstrate which neurons and circuits are affected at the earliest stages. Here, using patch-clamp recording and two-photon Ca(2+)

The palmitoyl acyltransferase DHHC2 regulates recycling endosome exocytosis and synaptic potentiation through palmitoylation of AKAP79/150.

Kevin M Woolfrey et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(2), 442-456 (2015-01-16)

Phosphorylation and dephosphorylation of AMPA-type ionotropic glutamate receptors (AMPARs) by kinases and phosphatases and interactions with scaffold proteins play essential roles in regulating channel biophysical properties and trafficking events that control synaptic strength during NMDA receptor-dependent synaptic plasticity, such as

Page 1 of 1