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Showing 1-30 of 88 results for "163678" within Papers
Journal of the Chemical Society. Perkin Transactions 1, 659-659 (1992)
Zhaobing Ding et al.
Journal of gastroenterology and hepatology, 28(1), 188-201 (2012-09-20)
Hepatic fibrosis is a worldwide healthy burden associated with significant morbidity and mortality. It is caused by a variety of chronic liver injuries. There is currently no effective treatment for liver fibrosis. In this report, we tested an imidazolium salt
Padmanathan Karthick Kannan et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(26), 9355-9359 (2015-05-23)
Nanostructured NiS thin film was prepared by a one-step electrodeposition method and the structural, morphological characteristics of the as-prepared films were analyzed by X-ray diffractometry (XRD), field emission scanning electron microscopy (FESEM) and energy dispersive X-ray analysis (EDAX). The electrocatalytic
Effect of molecular structure on the efficiency of amides and thiosemicarbazones used for corrosion inhibition of mild steel in hydrochloric acid
EE Ebenso, et al.
Materials Chemistry and Physics, 60, 79-90 (1999)
Syed Muhammad Shahid et al.
Pakistan journal of pharmaceutical sciences, 26(5), 853-857 (2013-09-17)
Angiotensin converting enzyme (ACE) is a key player of Renin Angiotensin System (RAS), involved in conversion of active product, angiotensin-II. Alterations in RAS have been implicated in the pathophysiology of various diseases involving heart, kidney, lung and liver. This study
Kate M Dudek et al.
The Biochemical journal, 453(1), 71-82 (2013-04-17)
Recent work has demonstrated the importance of post-transcriptional gene regulation in toxic responses. In the present study, we used two rat models to investigate mRNA translation in the liver following xenobiotic-induced toxicity. By combining polysome profiling with genomic methodologies, we
Yeon Ji Chae et al.
Gut and liver, 13(4), 450-460 (2019-01-04)
For the clinical application of stem cell therapy, functional enhancement is needed to increase the survival rate and the engraftment rate. The purpose of this study was to investigate functional enhancement of the paracrine effect using stem cells and hepatocyte-like
Tung-Ming Leung et al.
Laboratory investigation; a journal of technical methods and pathology, 93(10), 1082-1089 (2013-09-04)
To date, considerable progress has been made both in the mechanisms driving liver fibrosis and in the prevention of disease progression. Resolution of liver fibrosis is an emerging field in hepatology; yet, the mediators involved remain elusive. Earlier work from
Amr Y Esmat et al.
Nutrition (Burbank, Los Angeles County, Calif.), 29(1), 258-267 (2012-10-23)
The identification of the active phenolic compounds in the mixed extract of sea cucumber (Holothuria atra) body wall by high-performance liquid chromatography and an assessment of its hepatoprotective activity against thioacetamide-induced liver fibrosis in rats. Female Swiss albino rats were
Infrared Spectra and Normal Vibrations of Thioamides. II. Thioacetamide.
Suzuki I.
Bulletin of the Chemical Society of Japan, 35(9), 1449-1456 (1962)
Xiao-Wei Zhang et al.
Autophagy, 16(5), 782-796 (2019-07-10)
Impaired macroautophagy/autophagy is involved in the pathogenesis of hepatic fibrosis. However, how aberrant autophagy promotes fibrosis is far from understood. Here, we aimed to define a previously unrevealed pro-fibrotic mechanism for the stress protein TRIB3 (tribbles pseudokinase 3)-mediated autophagy dysfunction.
Sedat Dogan et al.
Nanoscale, 7(11), 4875-4883 (2015-02-13)
Solution-processable, two-dimensional semiconductors are promising optoelectronic materials which could find application in low-cost solar cells. Lead sulfide nanocrystals raised attention since the effective band gap can be adapted over a wide range by electronic confinement and observed multi-exciton generation promises
S Sehati et al.
Journal of colloid and interface science, 462, 130-139 (2015-10-11)
In this paper, the degradation of Congo red (CR) as a dye was investigated by a new synthetic photocatalyst. The synthesis was done through the intercalation of CdS in the layers of titanate (K2Ti4O9) by the assistance of ultrasound. The
Chuan-Feng Huang et al.
Journal of gastroenterology, 50(4), 480-490 (2014-08-27)
Chronic hepatitis B virus (HBV) infection, which can lead to hepatic disease, has become a critical national healthcare problem, and many people die each year as a result of HBV infection and its complications. Although microRNA-33a (miR-33a) is a novel
Udomsri Showpittapornchai et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 95 Suppl 12, S99-104 (2013-03-22)
About eighteen percent of cirrhotic patients come along with decreased systemic arterial oxygenation and expansion of pulmonary venous plexus which triggered by nitric oxide. The level of nitrate and iNOS significantly increase in the cirrhotic patients. However the localization of
Pedro Elias Marques et al.
Hepatology (Baltimore, Md.), 61(1), 348-360 (2014-05-16)
Drug-induced liver injury (DILI) is an important cause of acute liver failure, with limited therapeutic options. During DILI, oncotic necrosis with concomitant release and recognition of intracellular content amplifies liver inflammation and injury. Among these molecules, self-DNA has been widely
Jie Yu et al.
Theranostics, 5(9), 931-945 (2015-07-15)
The ability to selectively destroy cancer cells while sparing normal tissue is highly desirable during the cancer therapy. Here, magnetic targeted photothermal therapy was demonstrated by the integration of MoS2 (MS) flakes and Fe3O4 (IO) nanoparticles (NPs), where MoS2 converted
Kang Sun et al.
Biochimica et biophysica acta, 1840(7), 2105-2111 (2014-03-13)
Mammalian thioredoxin reductases (TrxR) are selenoproteins with important roles in antioxidant defense and redox regulation, principally linked to functions of their main substrates thioredoxins (Trx). All major forms of TrxR are intracellular while levels in serum are typically very low.
Zhaoqiang Ding et al.
Materials science & engineering. C, Materials for biological applications, 48, 469-479 (2015-01-13)
A novel molecularly imprinted optosensing material based on multi-walled carbon nanotube-quantum dots (MWCNT-QDs) has been designed and synthesized for its high selectivity, sensitivity and specificity in the recognition of a target protein bovine serum albumin (BSA). Molecularly imprinted polymer coated
Feng Hong et al.
Digestive diseases and sciences, 58(1), 257-264 (2012-08-25)
Sorafenib, which is approved for treatment of HCC, has also shown promising antifibrotic activity, and therefore refinement of its dosing requirements and window of efficacy are important goals prior to antifibrotic clinical trials. The purpose of this study was to
Kota Kaneko et al.
Hepatology (Baltimore, Md.), 61(6), 2056-2066 (2015-01-13)
Serving as the center for metabolism and detoxification, the liver is inherently susceptible to a wide variety of damage imposed by toxins or chemicals. Induction of cell populations with biliary epithelial phenotypes, which include progenitor-like cells and are referred to
O M E Abdel Salam et al.
European review for medical and pharmacological sciences, 17(6), 735-744 (2013-04-24)
The aim of the present study was to investigate the effect of the serotonin selective reuptake inhibitors (SSRIs) fluoxetine and sertraline and the tricyclic drug imipramine on oxidative stress in the brain and liver caused by thioacetamide in rats. Drugs
Ko Omura et al.
The Journal of toxicological sciences, 39(5), 785-794 (2014-09-23)
We previously reported a toxicogenomics-based prediction model for hepatocarcinogens in which the expression patterns of signature genes following repeated doses of either genotoxic or non genotoxic compounds were similar. Based on the results of our prediction model, we hypothesized that
Heather Hajovsky et al.
Chemical research in toxicology, 25(9), 1955-1963 (2012-08-08)
The hepatotoxicity of thioacetamide (TA) has been known since 1948. In rats, single doses cause centrolobular necrosis accompanied by increases in plasma transaminases and bilirubin. To elicit these effects, TA requires oxidative bioactivation, leading first to its S-oxide (TASO) and
Montinee Khunvirojpanich et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 96 Suppl 1, S71-S77 (2013-06-04)
In order to detoxify ammonia, mammalian livers use carbamoyl phosphate synthetase (CPS) and glutamine synthetase (GS) for conversion into respective non-toxic urea and glutamine. CPS is expressed in the periportal hepatocytes whereas GS is contained in the pericentral hepatocytes. To
Yong-Jun Dai et al.
Developmental and comparative immunology, 97, 28-37 (2019-03-27)
The aim of this article is to investigate the mechanism of lipotoxicity induced by high-fat diets (HFD) in Megalobrama amblycephala. In the present study, fish (average initial weight 40.0 ± 0.35 g) were fed with two fat levels (6% and 11%) diets with
D Mladenovic et al.
Human & experimental toxicology, 32(1), 90-100 (2012-11-01)
Thioacetamide (TAA) is widely used as a model of hepatic encephalopathy (HE). The aim of our study was to investigate the effects of TAA on electroencephalographic (EEG) changes in rats and to compare them with human HE. Male Wistar rats
Synthesis of nickel sulfide powders by thioacetamide in the presence of urea.
Grau J and Akinc M.
Journal of the American Ceramic Society. American Ceramic Society, 80(4), 941-951 (1997)
Hyeon Tae Kang et al.
Digestive diseases and sciences, 64(3), 781-791 (2018-11-14)
Injecting MSCs via blood vessel is most commonly used method, which has a major drawback of safety. The aim of our study was to evaluate efficacy using scaffold-loaded MSCs in acute liver failure model. Acute liver failure was induced in
Synthesis of copper sulfide nanowhisker via sonochemical way and its characterization
Xu C, et al
Chemistry Letters (Jpn), 32(2), 198-199 (2003)
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