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Showing 1-30 of 4302 results for "179337" within Papers
D Q Li et al.
Journal of chromatography. A, 1345, 50-56 (2014-05-06)
Xanthine oxidase (XO) can catalyze hypoxanthine and xanthine to generate uric acid and reactive oxygen species (ROS), including superoxide anion radical (O₂(•-)) and hydrogen peroxide. XO inhibitors and free radical scavengers are beneficial to the treatment of gout and many
Johanna Sápi et al.
PloS one, 10(11), e0142190-e0142190 (2015-11-06)
Bevacizumab is an exogenous inhibitor which inhibits the biological activity of human VEGF. Several studies have investigated the effectiveness of bevacizumab therapy according to different cancer types but these days there is an intense debate on its utility. We have
Dafni Dimakopoulou-Papazoglou et al.
Food microbiology, 53(Pt B), 76-81 (2015-12-19)
The effect of pH and water activity (aw) on the formation of biofilm by Salmonella enterica ser. Newport, previously identified as a strong biofilm producer, was assessed. Biofilm formation was evaluated in tryptone soy broth at 37 °C and at different
Johanna Krippner et al.
Journal of agricultural and food chemistry, 63(14), 3646-3653 (2015-03-31)
Uptake of perfluoroalkyl acids (PFAAs) by maize represents a potential source of exposure for humans, either directly or indirectly via feed for animals raised for human consumption. The aim of the following study was, therefore, to determine the accumulation potential
Ana R Ribeiro et al.
Journal of chromatography. A, 1418, 140-149 (2015-10-04)
The fate and removal of organic micropollutants in the environment is a demanding issue evidenced by the recent European policy. This work presents an analytical method for the trace quantification of 37 micropollutants including Priority Substances (Directive 2013/39/EU), substances of
Panfeng Yu et al.
Journal of chromatography. A, 1348, 27-33 (2014-05-20)
In this paper, polyethylene glycol modified (PEGylated) magnetic carbon nanotubes were developed as solid-phase extraction nanosorbents for the determination of methylprednisolone in rat plasma. The procedure mainly involved two steps including preparation of PEGylated magnetic nanosorbents and bioanalysis. Monodisperse magnetites
Weihao Wang et al.
Steroids, 95, 51-65 (2015-01-13)
Dioscorea panthaica is a traditional Chinese medicinal herb used in the treatment of various physiological conditions, including cardiovascular disease, gastropathy and hypertension. Steroidal saponins (SS) are the main active ingredients of this herb and have effects on myocardial ischemia and
Er-Bao Zhang et al.
Medical oncology (Northwood, London, England), 31(5), 914-914 (2014-03-29)
Gastric cancer (GC) is one of the most frequent cancers worldwide. Recent studies have shown that long noncoding RNAs (lncRNAs) play critical roles in multiple biological processes, including oncogenesis. The present study aimed to evaluate the potential role of lncRNA
Mamatha Garige et al.
Biochemical and biophysical research communications, 467(2), 275-281 (2015-10-10)
The molecular basis for nutraceutical properties of the polyphenol curcumin (Curcuma longa, Turmeric) is complex, affecting multiple factors that regulate cell signaling and homeostasis. Here, we report the effect of curcumin on cellular and developmental mechanisms in the eukaryotic model
Eun Ju Choi et al.
Chemistry & biology, 22(9), 1270-1279 (2015-08-25)
Low-nutrient media and long incubation times facilitated the cultivation of 20 taxonomically diverse Gram-negative marine bacteria within the phyla Bacteroidetes and Proteobacteria. These strains comprise as many as three new families and include members of clades that had only been
Martina Bolechová et al.
Food chemistry, 170, 265-270 (2014-10-13)
Alkaloids known as secondary metabolites are grouped by typical structural characteristics into large families such as pyrrolizidine alkaloids (PAs) comprising more than 350 individual heterocyclic compounds. The PAs present a serious health risk to human and livestock; hence there is
Chengcheng Peng et al.
Biomedical chromatography : BMC, 29(3), 425-436 (2014-07-22)
Shexiang Baoxin pills (SBP) are a traditional Chinese medicine that are used for treating coronary heart disease. Ginsenosides are the main effective components of SBP, but a comprehensive and deep pharmacokinetic study of ginsenosides in SBP, including multiple dosing and
Jessica A Cottrell et al.
Analytical biochemistry, 469, 34-42 (2014-12-03)
This article describes a new method for extracting RNA, protein, and lipid mediators from a single tissue specimen. Specifically, mouse bone fracture callus specimens were extracted into a single solution that was processed using three different procedures to measure messenger
Amandeep Kaur et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 69(3-4), 110-116 (2014-05-31)
The antileishmanial activity of extracts and phytoconstituents of Moringa oleifera Lam. was investigated in vitro against promastigotes of Leishmania donavani. The 70% ethanolic extract of roots and the methanolic extract of leaves showed moderate inhibitory activity with IC50 values of
Paul R Elliott et al.
Scientific reports, 5, 16826-16826 (2015-11-21)
This paper proposes a mechanism of controlling the diameter and separation of metallic nanorods from physical vapor deposition through self-organized seeds and experimentally demonstrates the feasibility using Ag as the prototype metal, In as the seed, and Si the substrate.
Francesca Catenia et al.
Natural product communications, 10(11), 1833-1838 (2016-01-12)
The phytochemical investigation of the methanolic extract of the white rot fungus Meripilus giganteus resulted in the isolation and identification of complex mixtures of free fatty acids (1), monoacylglycerols (2), cerebrosides (3), ergosterol (4) and ergosterol peroxide (5). The structures
Dapeng Yan et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(48), 14942-14947 (2015-12-03)
FoxP3(+) T regulatory (Treg) cells have a fundamental role in immunological tolerance, with transcriptional and functional phenotypes that demarcate them from conventional CD4(+) T cells (Tconv). Differences between these two lineages in the signaling downstream of T-cell receptor-triggered activation have
Samantha A Radford et al.
Journal of agricultural and food chemistry, 62(29), 7085-7091 (2014-06-10)
A solid phase extraction method was developed to isolate four insecticide degradates from baby food that were measured subsequently using high-performance liquid chromatography-tandem mass spectrometry. The degradates [parent insecticide] measured were malathion dicarboxylic acid [malathion], 3,5,6-trichloro-2-pyridinol [chlorpyrifos, chlorpyrifos methyl] (TCPy)
Elisabetta Bertol et al.
Forensic science international, 243, 149-155 (2014-09-10)
We report on a case of repeated MDPV consumptions that resulted in severe psychosis and agitation prompting the concomitant abuse of benzodiazepines. A 27-year-old man was found irresponsive in his apartment and was brought to the emergency department (ED) of
Laura Jaime et al.
Journal of the science of food and agriculture, 95(4), 722-729 (2014-06-17)
In this work three different techniques were applied to extract dry leaves of spinach (Spinacia oleracea): solid-liquid extraction (SLE), pressurised liquid extraction (PLE) and supercritical fluid extraction (SFE) to investigate the influence of extraction solvent and technique on extracts composition
Yuanyuan Zhou et al.
Molecules (Basel, Switzerland), 20(10), 19252-19262 (2015-10-28)
Among the classes of identified natural products, triterpenoids, one of the largest families, have been studied extensively for their diverse structures and variety of biological activities, including antitumor effects. In the present study, a phytochemical study of the green walnut
Jiangbin Ye et al.
Cancer discovery, 4(12), 1406-1417 (2014-09-05)
The de novo synthesis of the nonessential amino acid serine is often upregulated in cancer. In this study, we demonstrate that the serine catabolic enzyme, mitochondrial serine hydroxymethyltransferase (SHMT2), is induced when MYC-transformed cells are subjected to hypoxia. In mitochondria
Yan Zhou et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 89, 107-115 (2014-12-08)
Combination therapies have been investigated to address the current challenges of anti-cancer therapeutics. In particular, a novel paradigm of combination therapy targeting both cancer stem/progenitor cells and bulk tumor cells is promising to improve the long-term therapeutic benefit against prostate
Y Sultan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 971, 89-93 (2014-10-02)
The performance of five different C18 chromatography analytical columns with different lengths, particle sizes and porosities were compared for analysis of ochratoxin A (OTA) in fungal cultures and raisin samples. Chromatographic parameters including retention time, limit of detection, limit of
Zhiming Xiao et al.
Journal of chromatography. A, 1418, 29-35 (2015-10-05)
Subcritical water extraction was investigated as a novel and alternative technology for the separation of trace amounts of chloramphenicol, thiamphenicol, florfenicol and its major metabolite florfenicol amine from poultry tissues and its results were compared with those of conventional shaking
Ritwika Ray et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 20(47), 15618-15624 (2014-10-07)
The present article describes novel oxidative protocols for direct esterification of alcohols. The protocols involve successful demonstrations of both "cross" and "self" esterification of a wide variety of alcohols. The cross-esterification proceeds under a simple transition-metal-free condition, containing catalytic amounts
Mohammad Asif Iqbal et al.
Journal of chromatography. A, 1373, 149-158 (2014-12-04)
In the analysis of biogenic volatile organic compounds (BVOCs) in ambient air, preparation of a sub-ppb level standard is an important factor. This task is very challenging as most BVOCs (e.g., monoterpenes) are highly volatile and reactive in nature. As
Fengxia Wu et al.
Aquatic toxicology (Amsterdam, Netherlands), 155, 43-51 (2014-06-30)
We studied the effects of endocrine disrupting compounds nonylphenol (NP) and letrozole (LE) on the male goldfish Carassius aumtus. Exposure to NP (20 μg l(-1)) alone caused a significant up-regulation in the expression of aromatase, estrogen receptors and vitellogenin (VTG)
Jianqing Ruan et al.
Chemical research in toxicology, 27(6), 1030-1039 (2014-05-20)
Pyrrolizidine alkaloids (PAs) are natural toxins widely distributed in plants. The toxic potencies of different PAs vary significantly. PAs are mono- or diesters of necine acids with a necine base. On the basis of the necine bases, PAs are classified
Erik Hanff et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 970, 44-52 (2014-09-23)
A specific, sensitive and fast LC-MS/MS method with positive electrospray ionization for the quantitative determination of nitrite in human plasma is reported. Added [(15)N]nitrite served as the internal standard (IS). Endogenous nitrite and IS were converted to their S-nitrosoglutathione (GSNO)
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