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Showing 1-30 of 374 results for "184861" within Papers
Zhonghao Jiang et al.
Nature, 572(7769), 341-346 (2019-08-02)
Salinity is detrimental to plant growth, crop production and food security worldwide. Excess salt triggers increases in cytosolic Ca2+ concentration, which activate Ca2+-binding proteins and upregulate the Na+/H+ antiporter in order to remove Na+. Salt-induced increases in Ca2+ have long
Jong-Jae Yi et al.
Biochemical and biophysical research communications, 533(4), 893-898 (2020-10-04)
Lipoxygenases (LOXs) are implicated in the biosynthesis of pro- and anti-inflammatory lipid mediators involved in immune cell signaling, most of which catalyze peroxidation of polyunsaturated fatty acids by distinct regio- and stereoselectivity. Current reports suggested that conserved amino acid, Gly
Muhammad Usman Jamil et al.
Archives of biochemistry and biophysics, 679, 108156-108156 (2019-10-21)
Recently, growing attention has been given to new classes of bioactive lipid mediators derived from ω-3 polyunsaturated fatty acids, such as docosahexaenoic acid (DHA), especially in the context of their role as endogenous signal modulators. One such molecule is 17-oxo-DHA
Cai-Xia Lei et al.
Comparative biochemistry and physiology. Part D, Genomics & proteomics, 33, 100633-100633 (2019-11-17)
Promoting highly unsaturated fatty acid (HUFA) uptake and deposition can improve nutritional value of farmed fish and reduce dietary fish oil addition. Previously, we found that the golden pompano Trachinotus ovatus liver HUFA content increased with the increasing of dietary
Kateryna Pierzynowska et al.
Journal of immunology research, 2020, 3813250-3813250 (2020-02-25)
The current study is aimed at highlighting the impact of enterally or parenterally applied immunoglobulins (Igs) on polyunsaturated fatty acid (PUFA) absorption in newborn pigs. Piglets were chosen as the appropriate model since they are born agammaglobulinemic and any effects
T Higuchi et al.
Human & experimental toxicology, 39(4), 500-513 (2019-12-27)
Methotrexate (MTX)-induced intestinal mucosal injury in animals has been studied to understand how MTX can cause gastrointestinal disorders, but the pathogenesis of gastrointestinal disorders is still uncertain. We have attempted to reveal how dietary factors influence intestinal toxicity due to
Vitor Jacó Antraco et al.
Nutrients, 13(2) (2021-03-07)
The increasing impact of obesity on global human health intensifies the importance of studies focusing on agents interfering with the metabolism and remodeling not only of the white adipose tissue (WAT) but also of the liver. In the present study
Daniela Kanno Mathias et al.
Food technology and biotechnology, 58(4), 411-422 (2021-01-29)
New sources of docosahexaenoic acid have recently been investigated aiming at infant formula fortification and dietary supplementation, among which the single cell oil with 40-50% of this acid. For this purpose, such an oil was blended with caprylic acid in
Aamir Salam Teeli et al.
Animal reproduction science, 211, 106230-106230 (2019-12-02)
Dietary n-3 polyunsaturated fatty acids (n-3 PUFA) improve utero-ovarian functions and embryonic survival in postpartum dairy cows. Because early embryonic mortality is the major cause of repeat breeding (RB) in cows, there was investigation of the effect of dietary supplementation
Bill Tachtsis et al.
Frontiers in physiology, 11, 563-563 (2020-06-26)
Accumulation of excess saturated free fatty acids such as palmitate (PAL) in skeletal muscle leads to reductions in mitochondrial integrity, cell viability and differentiation. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) counteract
Richard Raj Singh et al.
Journal of experimental botany, 71(14), 4271-4284 (2020-04-04)
Ascorbic acid (AA) is the major antioxidant buffer produced in the shoot tissue of plants. Previous studies on root-knot nematode (RKN; Meloidogyne graminicola)-infected rice (Oryza sativa) plants showed differential expression of AA-recycling genes, although their functional role was unknown. Our
Elizabeth M Corteselli et al.
Environmental research, 187, 109627-109627 (2020-05-18)
Dietary intake of the omega-3 family of polyunsaturated fatty acids (ω-3 FA) is associated with anti-inflammatory effects. However, unsaturated fatty acids are susceptible to oxidation, which produces pro-inflammatory mediators. Ozone (O3) is a tropospheric pollutant that reacts rapidly with unsaturated
Annie W Lin et al.
BMC public health, 21(1), 35-35 (2021-01-08)
Current evidence supports the adoption of healthy diet and physical activity (PA) behaviors in patients with polycystic ovary syndrome (PCOS), given the positive effects of those behaviors on physical well-being. An improved understanding of the associations between diet and PA
Daniel Maucher et al.
Molecules (Basel, Switzerland), 25(19) (2020-10-03)
Cellular processes fundamentally depend on protein expression control. At this, protein expression is regulated on the transcriptional and the post-transcriptional level. PUFAs are already known to affect gene transcription. The present study was conducted to answer the question whether PUFAs
Hao Jin et al.
Molecular biology reports, 48(2), 1171-1180 (2021-01-28)
A large body of research has demonstrated a synergistic anticancer effect between docosahexaenoic acid (DHA) and standard chemotherapy regimens against colorectal cancer (CRC). In this study, we investigated the chemotherapeutic potential of cotreatment with DHA and isoliquiritigenin (ISL) against CRC
Paulina Aldana-Hernández et al.
The Journal of nutritional biochemistry, 92, 108617-108617 (2021-03-12)
Choline is an essential nutrient required for various biological processes. Eggs, dairy, and meat are rich in phosphatidylcholine (PC), whereas cereal and legumes are rich in free choline. Excess dietary choline leads to increase plasma trimethylamine N-oxide (TMAO). Epidemiological studies
Shengdi Guo et al.
Frontiers in pharmacology, 11, 226-226 (2020-03-27)
Recently, chemodynamic therapy (CDT) has represented a new approach for cancer treatment with low toxicity and side effects. Nonetheless, it has been a challenge to improve the therapeutic effect through increasing the amount of reactive oxygen species (ROS). Herein, we
Hrafnhildur L Runolfsdottir et al.
Urolithiasis, 48(4), 337-344 (2020-05-14)
We have recently encountered patients incorrectly diagnosed with adenine phosphoribosyltransferase (APRT) deficiency due to misidentification of kidney stones as 2,8-dihydroxyadenine (DHA) stones. The objective of this study was to examine the accuracy of stone analysis for identification of DHA. Medical
Caiquan Zhao et al.
International journal of biological sciences, 16(3), 374-387 (2020-02-06)
In addition to functioning as an antioxidant, anti-inflammatory and age-defying cellular component, DHA impacts the immune system by facilitating the pathogen invasion. The mechanism through which DHA regulates immune suppression remains obscure. In our study, we postulated that DHA might
Rebecca Power et al.
Journal of personalized medicine, 10(2) (2020-05-30)
Omega-3 fatty acids (ω-3FAs), carotenoids, and vitamin E are important constituents of a healthy diet. While they are present in brain tissue, studies have shown that these key nutrients are depleted in individuals with mild cognitive impairment (MCI) in comparison
V I Pedroni et al.
Biochimica et biophysica acta. Biomembranes, 1863(6), 183584-183584 (2021-02-12)
This work investigates how docosahexaenoic acid (DHA) modifies the effect of Cholesterol (Chol) on the structural and dynamical properties of dipalmitoylphosphatidylcholine (DPPC) membrane. We employ low-cost and non-invasive methods: zeta potential (ZP), conductivity, density, and ultrasound velocity, complemented by molecular
Marjann Schäfer et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(2), 158550-158550 (2019-11-05)
The tree shrew (Tupaia belangeri) is a rat-sized mammal, which is more closely related to humans than mice and rats. However, the use of tree shrew to explore the patho-mechanisms of human inflammatory disorders has been limited since nothing is
Licai Cheng et al.
Life sciences, 257, 118036-118036 (2020-07-06)
Anti-obesity effects and improved leptin sensitivity from n-3 polyunsaturated fatty acids (n-3 PUFAs) have been reported in diet-induced obese animals. This study sought to determine the beneficial central effects and mechanism of docosahexaenoic acid (DHA, 22:6 n-3) in high-fat (HF)
Jun-Young Park et al.
Enzyme and microbial technology, 139, 109595-109595 (2020-08-01)
A novel lipoxygenase (BLOX) was purified from black soybean (Glycine max (L.) Merr.), and its catalytic properties were characterized. The molecular weight of BLOX was 101 kDa and its unique heterodimeric structure with two different subunits of molecular weight 46 kDa and
Wasundara Fernando et al.
Scientific reports, 10(1), 21391-21391 (2020-12-09)
Flavonoids are known to undergo phase II metabolism and produce metabolites with similar or stronger biological effects compared to the parent flavonoids. However, the limited cellular uptake and bioavailability restrict their clinical use. We synthesized phloridzin docosahexaenoate (PZ-DHA), a novel
Jian Yang et al.
Schizophrenia bulletin, 46(4), 804-813 (2020-01-11)
Psychiatric disorders are the leading cause of disability worldwide while the pathogenesis remains unclear. Genome-wide association studies (GWASs) have made great achievements in detecting disease-related genetic variants. However, functional information on the underlying biological processes is often lacking. Current reports
J Douglas Bremner et al.
Nutrients, 12(8) (2020-08-23)
There has long been an interest in the effects of diet on mental health, and the interaction of the two with stress; however, the nature of these relationships is not well understood. Although associations between diet, obesity and the related
Ran Chen et al.
OncoTargets and therapy, 13, 3375-3387 (2020-05-20)
Polarized M2 macrophages are an important type of tumor-associated macrophage (TAM), with roles in the growth, invasion, and migration of cancer cells in the tumor microenvironment. Dihydroartemisinin (DHA), a traditional Chinese medicine extract, has been shown to inhibit the progression
Marnie Newell et al.
Breast cancer research and treatment, 177(2), 357-367 (2019-06-27)
The objective of this study was to investigate if DHA dietary supplementation enhances the anticancer actions of docetaxel (TXT) in two different drug resistant triple negative breast cancer (TNBC) patient-derived xenografts (PDX)s. In two experiments, female NSG mice bearing TNBC
Luisa Ugolini et al.
Journal of the science of food and agriculture, 99(9), 4235-4241 (2019-02-26)
The antimicrobial activity of allyl-isothiocyanate (AITC) on plant pathogens is well known and has already been demonstrated in the strawberry with respect to Botritis cinerea fungal infection using postharvest biofumigation. In the present study, vapours of 0.08 mg L-1 of Brassica meal-derived
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