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Showing 31-60 of 374 results for "184861" within Papers
Zhengping Wu et al.
Die Pharmazie, 74(11), 675-679 (2019-11-20)
Docosahexaenoic acid (DHA) is rich in fish oil with many pharmacological impacts such as anti-inflammation and anti-cancer activities. In the present study, we aimed to investigate the inhibitory effects of DHA on the invasion and inflammation in prostate cancer cells.
Monise Helen Masuchi Buscato et al.
Food chemistry, 327, 127087-127087 (2020-05-27)
This study investigated the lipid oxidation reactions of furan fatty acids, long-chain ω-3 polyunsaturated fatty acids, and tocopherols in an enriched ω-3 fish oil to better understand their degradation kinetics. Furthermore, the influence of an added monomethyl furan fatty acid
Daniel González-Hedström et al.
Nutrients, 13(1) (2020-12-31)
Aging is associated with a progressive decline in skeletal muscle mass, strength and function (sarcopenia). We have investigated whether a mixture of algae oil (25%) and extra virgin olive oil (75%) could exert beneficial effects on sarcopenia. Young (3 months)
Yvoni Kyriakidou et al.
Journal of the International Society of Sports Nutrition, 18(1), 9-9 (2021-01-15)
Exercise-induced muscle damage (EIMD) results in transient muscle inflammation, strength loss, muscle soreness and may cause subsequent exercise avoidance. Omega-3 (n-3) supplementation may minimise EIMD via its anti-inflammatory properties, however, its efficacy remains unclear. Healthy males (n = 14, 25.07 ± 4.05 years) were randomised
María Carmen Sánchez et al.
Microorganisms, 9(2) (2021-03-07)
Microbial biofilm modeling has improved in sophistication and scope, although only a limited number of standardized protocols are available. This review presents an example of a biofilm model, along with its evolution and application in studying periodontal and peri-implant diseases.
Hyun-Woo Chun et al.
Journal of microbiology and biotechnology, 30(1), 85-92 (2019-11-07)
One of the omega-3 essential fatty acids, docosahexaenoic acid (DHA), is a significant constituent of the cell membrane and the precursor of several potent lipid mediators. These mediators are considered to be important in preventing or treating several diseases. Resolvin
Roman Jaramillo et al.
Journal of chromatography. A, 1612, 460696-460696 (2020-01-02)
Thermodynamic modeling of GC × GC separations provides a tool for rapid method evaluation and optimization. Separations of 95 hydrocarbons on two cryogenically modulated GC × GC systems (atmospheric outlet and vacuum outlet) are modeled, displaying average second dimension retention time modeling absolute errors
Amanda Lo Van et al.
Molecular neurobiology, 56(2), 986-999 (2018-06-03)
Docosahexaenoic acid (DHA, 22:6n-3) is an essential omega-3 polyunsaturated fatty acid (PUFA) that is required for proper brain development and cerebral functions. While DHA deficiency in the brain was shown to be linked to the emergence of cerebral diseases, a
Xiaoli Zhu et al.
Scientific reports, 10(1), 6448-6448 (2020-04-17)
Neonatal necrotizing enterocolitis (NEC) is a serious gastrointestinal disease with high death rate in premature infants. Fish oil (FO) and its constituents have been shown to ameliorate intestinal inflammation and mucosal damage. However, the underlying mechanism of action is not
Keiko Iwakoshi et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 36(7), 1020-1031 (2019-05-18)
In this study, a new method was developed for simultaneously determining nine preservatives, that is, benzoic acid (BA), sorbic acid (SOA), dehydroacetic acid (DHA) and PHBAs (methyl p-hydroxybenzoate [PHBA-me], ethyl p-hydroxybenzoate [PHBA-et], isopropyl p-hydroxybenzoate [PHBA-ipro], propyl p-hydroxybenzoate [PHBA-npro]), isobutyl p-hydroxybenzoate
Harvie P Portugaliza et al.
eLife, 9 (2020-10-22)
Malaria transmission is dependent on the formation of gametocytes in the human blood. The sexual conversion rate, the proportion of asexual parasites that convert into gametocytes at each multiplication cycle, is variable and reflects the relative parasite investment between transmission
Yong Yu et al.
Metabolic engineering, 56, 181-189 (2019-10-11)
Metabolic engineering of microorganisms for production of succinate from glycerol remains challenging. It was thought that energy supply is a severe problem for anaerobic fermentation of glycerol to produce succinate. In this study, an energy-conserving glycerol utilization pathway was recruited
Laís Ferraz Brito et al.
Journal of the science of food and agriculture, 99(13), 5870-5880 (2019-06-18)
Sepsis is a set of serious organic manifestations caused by an infection, whose progression culminates in exacerbated inflammation and oxidative stress, poor prognosis, and high hospital costs. Antioxidants used against sepsis have been evaluated, including essential oils such as β-caryophyllene
Danilo Cucchi et al.
Cardiovascular research, 116(5), 1006-1020 (2019-08-11)
Adaptive immunity contributes to the pathogenesis of cardiovascular metabolic disorders (CVMD). The omega-3 polyunsaturated fatty acids (n-3PUFA) are beneficial for cardiovascular health, with potential to improve the dysregulated adaptive immune responses associated with metabolic imbalance. We aimed to explore the
Hiroki Suganuma et al.
Prostaglandins, leukotrienes, and essential fatty acids, 164, 102217-102217 (2020-12-09)
Oxylipins synthesized by oxidation of long-chain polyunsaturated fatty acids (LCPUFAs) are bioactive downstream lipid mediators. The aim of this study was to describe oxylipin levels in preterm infants born 30 to 33 weeks' gestation who were enrolled in a randomized
Cuiping Shi et al.
Food chemistry, 298, 125029-125029 (2019-07-02)
Thermal processing methods have important effects on food lipids. In this work, ultra-high-performance liquid chromatography-Q-Extractive Orbitrap mass spectrometry and lipidsearch software were applied to analyze effect of three types of thermal processing methods on the lipidomics profile of tilapia fillets.
Peng Gao et al.
Life sciences, 242, 117221-117221 (2019-12-28)
Endothelial cell (EC) tube formation is crucial for tumor angiogenesis, which becomes a target for chemotherapy. The anti-malaria agent dihydroartemisinin (DHA) inhibited tumor growth and angiogenesis. The aim of this study was to investigate the effects of DHA on EC
Xingran Chen et al.
IUBMB life, 71(11), 1740-1750 (2019-07-03)
Alcoholic liver disease (ALD) is generated from excessive alcohol consumption, characterized by hepatic steatosis. Mechanistically, excessive hepatic lipid accumulation was attributed to the aberrant lipin-1 signaling during the development of alcoholic steatosis in rodent species and human. Dihydroartemisinin (DHA) has
Michael Armstrong et al.
Prostaglandins & other lipid mediators, 151, 106483-106483 (2020-10-01)
A liquid chromatography tandem mass spectrometry-based method for the quantitation of 39 lipid mediators in four sample types and in two mouse strains is described. The method builds upon existing methodologies for analysis of lipid mediators by A) utilizing a
Laura E Downie et al.
The Cochrane database of systematic reviews, 12, CD011016-CD011016 (2019-12-18)
Polyunsaturated fatty acid (PUFA) supplements, involving omega-3 and/or omega-6 components, have been proposed as a therapy for dry eye. Omega-3 PUFAs exist in both short- (alpha-linolenic acid [ALA]) and long-chain (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) forms, which largely
Steven C Perry et al.
Journal of lipid research, 61(7), 1087-1103 (2020-05-15)
The two oxylipins 7S,14S-dihydroxydocosahexaenoic acid (diHDHA) and 7S,17S-diHDHA [resolvin D5 (RvD5)] have been found in macrophages and infectious inflammatory exudates and are believed to function as specialized pro-resolving mediators (SPMs). Their biosynthesis is thought to proceed through sequential oxidations of
Megan P Caputo et al.
Brain, behavior, and immunity, 81, 455-469 (2019-07-05)
Neonatal brain development can be disrupted by infection that results in microglial cell activation and neuroinflammation. Studies indicate that polyunsaturated fatty acids (PUFAs) and their metabolites can resolve inflammation. It is not known if dietary PUFA increases lipid metabolites in
Yueyang Zhao et al.
Current Alzheimer research, 17(10), 916-925 (2020-12-18)
Alzheimer's disease (AD) is one of the worst neurodegenerative disorders worldwide, with extracellular senile plaques (SP), subsequent intracellular neurofibrillary tangles (NFTs) and final neuron loss and synaptic dysfunction as the main pathological characteristics. Excessive apoptosis is the main cause of
Fabio Correddu et al.
Foods (Basel, Switzerland), 8(7) (2019-07-03)
The fatty acid (FA), polyphenol content and evaluation of the antioxidant capacity of exhausted Myrtus communis berries (EMB) resulting from the production of myrtle liqueur were assessed. All parts of the exhausted berries exhibited high concentrations of carbohydrates, proteins, lipids
Sebastian Andris et al.
Journal of biotechnology, 317, 48-58 (2020-05-04)
Antibody-drug conjugates (ADCs) are hybrid molecules based on monoclonal antibodies (mAbs) with covalently attached cytotoxic small-molecule drugs. Due to their potential for targeted cancer therapy, they form part of the diversifying pipeline of various biopharmaceutical companies, in addition to currently
Xue Geng et al.
Molecular neurobiology, 57(2), 1085-1098 (2019-11-05)
Growing evidence suggests that docosahexaenoic acid (DHA) exerts neuroprotective effects, although the mechanism(s) underlying these beneficial effects are not fully understood. Here we demonstrate that DHA, but not arachidonic acid (ARA), suppressed oligomeric amyloid-β peptide (oAβ)-induced reactive oxygen species (ROS)
Daniel Hilger et al.
Science (New York, N.Y.), 369(6503) (2020-08-01)
Family B heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors (GPCRs) play important roles in carbohydrate metabolism. Recent structures of family B GPCR-Gs protein complexes reveal a disruption in the α-helix of transmembrane segment 6 (TM6) not observed in family A
Yusuke Yamamoto et al.
Analytical and bioanalytical chemistry, 413(1), 245-254 (2020-10-23)
Lysophosphatidylethanolamines (LysoPEs) are the partial hydrolysis products of phosphatidylethanolamine. Despite the unique in vitro bioactivities of LysoPEs, there are limited reports on the pathophysiological role of LysoPEs in the serum, due to the lack of sensitive analytical methods for determination
Mónica B Betancor et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 240, 110372-110372 (2019-11-02)
Elongation of very long-chain fatty acid 4 (Elovl4) proteins are involved in the biosynthesis of very long-chain (>C24) fatty acids and in many teleost fish species they are key enzymes in the pathway for the production of docosahexaenoic acid (DHA;
Bo Yang et al.
Psychotherapy and psychosomatics, 88(4), 215-224 (2019-07-04)
Endocannabinoids (ECs) are one type of bioactive endogenous neuroinflammatory mediator derived from polyunsaturated fatty acids (PUFAs), which may regulate the emotional processes. Here, we assessed the effect of ω-3 PUFAs on EC levels, which may be the novel targets for
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