Search Within
194123
Applied Filters:
Keyword:'194123'
Showing 1-30 of 137 results for "194123" within Papers
Michela Maestrini et al.
Molecules (Basel, Switzerland), 25(2) (2020-01-16)
Gastrointestinal strongyle nematodes (GIS) are included among the most important parasites of small ruminants. The widespread drug resistance and drug residues in products of animal origin have increased the interest in the search for natural compounds with anthelmintic activity as
Dan Zou et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 98, 359-366 (2012-09-22)
With the compound [Zn(HL(1))(2)(Py)] (H(2)L(1)=2-(1H-benzo[d]imidazol-2-yl)-6-methoxyophenol), Py=pyridine) or [Zn(HL(2))(2)(Py)] (H(2)L(2)=2-(1H-benzo[d]imidazol-2-yl)-4-bromo-6-methoxyphenol) as the precursor, complexes [ZnLn(HL(1))(2)(Py)(NO(3))(3)] (Ln=Nd, 1; Ln=Gd, 2) or [ZnLn(HL(2))(2)(Py)(NO(3))(3)] (Ln=Nd, 3; Ln=Gd, 4) were obtained by the further reaction with Ln(NO(3))(3)·6H(2)O (Ln=Nd or Gd). The result of their photophysical
Lyara Ferreira Pereira et al.
Ultrasonics sonochemistry, 69, 105275-105275 (2020-08-02)
In this work, Zn-based coordination polymer [Zn2(1,3-bdc)bzim2]n was successfully synthesized by the sonochemical method using a 13 mm probe-type ultrasound operating at 20 kHz and amplitudes of 30, 40 and 50% corresponding to an acoustic power of 5.5, 8.6, and 10.3 W, respectively.
Haitao Liu et al.
Anti-cancer drugs, 26(6), 667-677 (2015-03-27)
Coumarins are a large family of compounds derived from a wide range of plants, fungi, and bacteria, and coumarin derivatives can have extremely variable structures and consequently diverse biological properties including antitumor activity. Compounds that bear a benzimidazole moiety are
Wang Zhang et al.
ACS nano, 14(2), 1971-1981 (2020-01-31)
The development of highly efficient electrocatalysts to reduce overpotentials is vital for accelerating the sluggish oxygen evolution reaction (OER) processes. Herein, we demonstrate ultrathin heterogeneous nanosheets as a promising OER electrocatalyst, which are composed of ultrafine CoFeOx nanoparticles and a
Su Jung Bae et al.
Biochemical and biophysical research communications, 487(2), 409-414 (2017-04-19)
Bone mass is controlled by a balance between bone resorption and formation by osteoclasts and osteoblasts, respectively. An imbalance between osteoblasts and osteoclasts increases the risk of osteoporosis and fractures. Although inhibition of osteoclasts is beneficial for preventing and treating
Chiara Perruchon et al.
Applied microbiology and biotechnology, 101(9), 3881-3893 (2017-02-06)
Thiabendazole (TBZ) is a fungicide used in fruit-packaging plants. Its application leads to the production of wastewaters requiring detoxification. In the absence of efficient treatment methods, biological depuration of these effluents could be a viable alternative. However, nothing is known
Sofia Montalvão et al.
Archiv der Pharmazie, 349(2), 137-149 (2015-12-29)
A series of 2-aminobenzothiazole and benzimidazole analogs based on the clathrodin scaffold was synthesized and investigated for their antimicrobial and antiproliferative activities as well as for their effects in hepatitis C virus (HCV) replicon model. Compound 7, derived from 2-aminobenzothiazole
Nik Khairunissa Nik Abdullah Zawawi et al.
Bioorganic chemistry, 64, 29-36 (2015-12-08)
Newly synthesized benzimidazole hydrazone derivatives 1-26 were evaluated for their α-glucosidase inhibitory activity. Compounds 1-26 exhibited varying degrees of yeast α-glucosidase inhibitory activity with IC50 values between 8.40 ± 0.76 and 179.71 ± 1.11 μM when compared with standard acarbose.
Laila Arzuman et al.
Anticancer research, 34(10), 5453-5464 (2014-10-03)
In the present study, synergism in activity from the sequenced combinations of monofunctional platinum tris(benzimidazole)monochloroplatinum(II) chloride (coded as LH4) with capsaicin, quercetin, curcumin and cisplatin was investigated as a function of sequence of administration in a number of human ovarian
Zhaoyang Li et al.
The Journal of clinical investigation, 125(3), 1081-1097 (2015-02-03)
Signaling via the MyD88/IRAK pathway in T cells is indispensable for cell survival; however, it is not known whether this pathway functions in the progression of T acute lymphoblastic leukemia (T-ALL). Here, we determined that compared with thymic and peripheral
Docking investigation and binding interaction of benzimidazole derivative with bovine serum albumin.
J Jayabharathi et al.
Journal of photochemistry and photobiology. B, Biology, 117, 27-32 (2012-10-03)
(1)H NMR, (13)C NMR and Mass spectral analysis have been made for 1-(4-fluorobenzyl)-2-(4-fluorophenyl)-1H-benzo[d]imidazole (FBFPB). The mutual interaction of FBFPB with bovine serum albumin (BSA) was investigated using absorption, fluorescence and synchronous fluorescence spectral studies. The binding distance has been determined
Jingshuai Yang et al.
ChemSusChem, 6(2), 275-282 (2013-01-11)
Covalently cross-linked polymer membranes were fabricated from poly(aryl sulfone benzimidazole) (SO(2)PBI) and poly(vinylbenzyl chloride) (PVBCl) as electrolytes for high-temperature proton-exchange-membrane fuel cells. The cross-linking imparted organo insolubility and chemical stability against radical attack to the otherwise flexible SO(2)PBI membranes. Steady
Virginie Barrère et al.
Parasitology international, 62(5), 464-470 (2013-06-19)
Haemonchus contortus is a hemophilic nematode which infects sheep and causes anemia and death to lambs. Benzimidazole drugs are used to remove these parasites, but the phenomenon of resistance has arisen worldwide. A sensitive test to detect resistance before treatment
Mohammad Sajid et al.
Cancer medicine, 8(1), 246-260 (2018-12-24)
Cancer is one of the major health problem globally, responsible for high morbidity and mortality. Exposure of humans to xenobiotics is associated with the development of cancer. Further, these xenobiotics may combine with the body proteins and can act as
Rym Chioukh et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(12), 2041-2048 (2014-09-23)
The coadministration of methotrexate (MTX) and proton pump inhibitors (PPIs) can result in a pharmacokinetic interaction that delays MTX elimination and subsequently increases the MTX blood concentrations. Human organic anion transporters (hOATs) are responsible for the renal tubular secretion of
Benjamin W Roose et al.
Biochemistry, 58(30), 3232-3242 (2019-06-30)
Indole prenyltransferases catalyze the prenylation of l-tryptophan (l-Trp) and other indoles to produce a diverse set of natural products in bacteria, fungi, and plants, many of which possess useful biological properties. Among this family of enzymes, CymD from Salinispora arenicola
J F Humbert et al.
Veterinary parasitology, 101(3-4), 405-414 (2001-11-15)
Molecular techniques are of growing importance in the study of anthelmintic resistance in trichostrongylid worm populations. A knowledge of the genetic determinants of benzimidazole (BZ) resistance has made it possible to construct a molecular tool for genotyping individual worms, in
Chun-Yu Chang et al.
Toxicology and applied pharmacology, 279(3), 351-363 (2014-07-16)
Oxidized LDL (oxLDL) induces a pro-oxidative environment and promotes apoptosis, causing the progression of renal diseases in humans. Taurine is a semi-essential amino acid in mammals and has been shown to be a potent endogenous antioxidant. The kidney plays a
Fabian López-Vallejo et al.
Bioorganic & medicinal chemistry, 15(2), 1117-1126 (2006-11-01)
Comparative molecular field analysis (CoMFA) was performed on a set of 1H-benzimidazole derivatives. Molecular modeling and 3D-QSAR were employed to determine the tautomeric form that would probably fit a target receptor in Entamoeba histolytica. CoMFA results suggest that the antiamoebic
Jiumao Lin et al.
BMC cancer, 14, 729-729 (2014-10-01)
The development of hepatic cancer is tightly regulated by multiple intracellular signaling pathways. Therefore, most currently-used anti-tumor agents, which typically target single intracellular pathway, might not always be therapeutically effective. Additionally, long-term use of these agents probably generates drug resistance
Christina T K Wales et al.
Anti-cancer drugs, 26(6), 657-666 (2015-03-27)
Drugs containing the benzimidazole carbamate scaffold include anthelmintic and antifungal agents, and they are now also recognized as having potential applications in the treatment of colorectal and other cancers. These agents act by binding to β-tubulin, and in doing so
Theany To et al.
Nature communications, 11(1), 2593-2593 (2020-05-24)
Metal-organic framework glasses feature unique thermal, structural, and chemical properties compared to traditional metallic, organic, and oxide glasses. So far, there is a lack of knowledge of their mechanical properties, especially toughness and strength, owing to the challenge in preparing
Mar Oroval et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 23(6), 1353-1360 (2016-11-20)
We describe herein the preparation of glucose-sensitive capped mesoporous silica nanoparticles for insulin delivery. The new material consists of an expanded-pore nanometric silica support grafted with 1-propyl-1-H-benzimidazole groups, loaded with fluorescein isothiocyanate-labeled insulin (FITC-Ins) and capped by the formation of
Neil D Sargison et al.
International journal for parasitology. Drugs and drug resistance, 10, 92-100 (2019-08-20)
Anthelmintic resistant gastrointestinal helminths have become a major cause of poor health in sheep and goats. Sensitive and specific molecular markers are needed to monitor the genotypic frequency of resistance in field parasite populations. Gastrointestinal nematode resistance to benzimidazole is
Venkatasubramanian Ulaganathan et al.
Journal of the American Chemical Society, 135(6), 2263-2272 (2013-01-12)
Human kinesin Eg5 is a target for drug development in cancer chemotherapy with compounds in phase II clinical trials. These agents bind to a well-characterized allosteric pocket involving the loop L5 region, a structural element in kinesin-5 family members thought
Mohammad Mahdi Najafpour et al.
Dalton transactions (Cambridge, England : 2003), 42(4), 879-884 (2012-11-28)
In this communication, we report the synthesis, characterization, and electrochemistry of a 2-(2-hydroxyphenyl)-1H-benzimidazole-manganese oxide hybrid. Our results suggest that this compound is a promising model for the manganese cluster together with tyrosine-161 and histidine-190 in photosystem II of plants, algae
Moshe Ronen et al.
Pathogens (Basel, Switzerland), 8(4) (2019-12-05)
Net blotch (NB) is a major disease of barley caused by the fungus Pyrenophora teres f. teres (Ptt), and P. teres f. maculata (Ptm). Ptt and Ptm infect the cultivated crop (Hordeum vulgare) and its wild relatives (H. vulgare ssp.
Tamara Muñoz-Caro et al.
Parasites & vectors, 8, 607-607 (2015-11-28)
Polymorphonuclear neutrophil (PMN) and eosinophil extracellular trap (ETs) formation has recently been described as an important host effector mechanism against invading pathogens. So far, scarce evidence on metazoan-triggered ET formation has been published. We here describe for the first time
Magdalena J Mazur et al.
Plant physiology, 179(1), 168-183 (2018-11-06)
Attachment of the small ubiquitin-like modifier (SUMO) to substrate proteins modulates their turnover, activity, or interaction partners. However, how this SUMO conjugation activity concentrates the proteins involved and the substrates into uncharacterized nuclear bodies (NBs) remains poorly understood. Here, we
Page 1 of 5