Omar N Al Safarjalani et al.
Cancer chemotherapy and pharmacology, 69(6), 1449-1455 (2012-03-01)
The purpose of this investigation was to evaluate the effectiveness of oral 5-(phenylthio)acyclouridine (PTAU) in reducing 5-fluorouracil (FUra) host toxicity and enhancing its chemotherapeutic efficacy against human breast tumors. PTAU is a potent and specific inhibitor of uridine phosphorylase (UP