nd
ed.; P. Liang et al., eds.). Humana Press
(Totowa, NJ), Vol. 317, Chapter 14, pp. 219-242
(2006).
ND,SU,GCY,MAM 11/18-1
2018 Sigma-Aldrich Co. LLC. All rights reserved. SIGMA-ALDRICH
active V617F mutant
(IC50 = 78 and 206 nM, respectively).
5 mg 420139
JAK3 Inhibitor VI A cell-permeable, potent, and reversible inhibitor of JAK3 (IC50 = 27 nM). 5 mg 420126
STAT3 Inhibitor III
continued)
D. Preparation of lyophilized Cell Lysates (Catalog #47-206, 47-241, 47-242)
Jurkat T Cell Lysate: Unstimulated (#47-206) is provided as a lyophilized stock of cell
lysate prepared from
Material: HDPE, undyed
Nominal volume: 25 L
Weight: min. 1.25 kg
Height: 488 mm
Width: 242 mm
Length: 295 mm
Mouth: S60x6
Opening: 47.2 mm
Closure
Name: S60x6
Material: HDPE
Amino-5-(N-tert-butyl-
sulfonamido-4-phenyl)-indazole
420139 A potent inhibitor of both the wild-type JAK2 and the
constitutively active V617F mutant (IC50 = 78 and 206 nM,
respectively).
5 mg
replacement balls into the cylinder.
5. Insert the O-ring in the groove so that it seats completely.
6. Run the Lock Door recipe to close secure the door.
206 User Guide
n/d
239 E2F1 E9026 1869 E2F1 P NP_005216.1 y n/d n/d
241 E2F1 E8901 1869 E2F1 M NP_005216.1 y y y
242 E2F2 E8776 1870 E2F2 M NP_004082.1 y n/d n/d
243 E2F3 E8651 1871 E2F3 M NP_001940.1 y n/d n/d
244 E2F4
n/d
239 E2F1 E9026 1869 E2F1 P NP_005216.1 y n/d n/d
241 E2F1 E8901 1869 E2F1 M NP_005216.1 y y y
242 E2F2 E8776 1870 E2F2 M NP_004082.1 y n/d n/d
243 E2F3 E8651 1871 E2F3 M NP_001940.1 y n/d n/d
244 E2F4