208-679-7

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[The changes of PTEN/Akt1 expression and cell proliferation in pulmonary arterial smooth muscle cells induced by hypoxia in rats].

Bin Yi et al.

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 31(8), 586-590 (2008-12-17)

To observe the changes of PTEN/Akt1 mRNA and protein expression level in pulmonary arterial smooth muscle cells (PASMC) induced by hypoxia in rats, and to investigate the role of PTEN/Akt1 signaling pathway in hypoxic pulmonary hypertension (HPH). Pure PASMCs were

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